Results 11 to 20 of about 1,520,222 (341)
Caveolins and Lung Function [PDF]
, 2012 The primary function of the mammalian lung is to facilitate diffusion of oxygen to venous blood and to ventilate carbon dioxide produced by catabolic reactions within cells. However, it is also responsible for a variety of other important functions, including host defense and production of vasoactive agents to regulate not only systemic blood pressure,
Maniatis, N.A. +3 more
openaire +3 more sources
Respirology Case Reports, 2020 We report the genetic variants associated with alpha‐1 antitrypsin deficiency (AATD) in 117 patients admitted to our outpatient clinic and characterized by a serum concentration of AAT lower than 113 mg/dL.
Marina Aiello +5 more
doaj +1 more source
Muscles and lungs: fatal attraction, but time for intervention
Monaldi Archives for Chest Disease, 2005 -
J.C. Winck, M. Gonçalves
doaj +1 more source
Pharmaceutics, 2022 Despite females being more often affected by asthma than males and the prevalence of COPD rising in females, conflicting evidence exists as to whether sex may modulate the correct inhaler technique.
Luigino Calzetta +6 more
doaj +1 more source
Clinical manifestations of a new alpha‐1 antitrypsin genetic variant: Q0parma
Respirology Case Reports, 2022 Alpha‐1 antitrypsin deficiency is an autosomal, codominant disorder caused by mutations of the SERPINA1 gene. Several mutations of SERPINA1 have been described associated with the development of pulmonary emphysema and/or chronic liver disease and ...
Marina Aiello +9 more
doaj +1 more source
Investigational Treatments in Phase I and II Clinical Trials: A Systematic Review in Asthma
Biomedicines, 2022 Inhaled corticosteroids (ICS) remain the mainstay of asthma treatment, along with bronchodilators serving as control agents in combination with ICS or reliever therapy.
Luigino Calzetta +6 more
doaj +1 more source
Cells, 2022 COPD is an incurable disorder, characterized by a progressive alveolar tissue destruction and defective mechanisms of repair and defense leading to emphysema.
Luigino Calzetta +6 more
doaj +1 more source
Improving spirometry testing by understanding patient preferences
ERJ Open Research, 2021 The American Thoracic Society and European Respiratory Society commissioned a task force to update the technical standards for spirometry testing with the aim of increasing the accuracy, precision and quality of spirometry measurements and improving the ...
Barbara Johnson +3 more
doaj +1 more source
Childhood lung function as a determinant of menopause-dependent lung function decline [PDF]
Maturitas, 2021 The naturally occurring age-dependent decline in lung function accelerates after menopause, likely due to the change of the endocrine balance. Although increasing evidence shows suboptimal lung health in early life can increase adult susceptibility to insults, the potential effect of poor childhood lung function on menopause-dependent lung function ...
Kai Triebner +17 more
openaire +3 more sources
β3-Adrenoceptor redistribution impairs NO/cGMP/PDE2 signalling in failing cardiomyocytes
eLife, 2020 Cardiomyocyte β3-adrenoceptors (β3-ARs) coupled to soluble guanylyl cyclase (sGC)-dependent production of the second messenger 3’,5’-cyclic guanosine monophosphate (cGMP) have been shown to protect from heart failure.
Sophie Schobesberger +9 more
doaj +1 more source