Results 11 to 20 of about 12,551,552 (363)
Respirology Case Reports, 2020 We report the genetic variants associated with alpha‐1 antitrypsin deficiency (AATD) in 117 patients admitted to our outpatient clinic and characterized by a serum concentration of AAT lower than 113 mg/dL.
Marina Aiello +5 more
doaj +1 more source
Natural history of lung function in spinal muscular atrophy
Orphanet Journal of Rare Diseases, 2020 Background Respiratory muscle weakness is an important feature of spinal muscular atrophy (SMA). Progressive lung function decline is the most important cause of mortality and morbidity in patients.
C. Wijngaarde +14 more
semanticscholar +1 more source
Muscles and lungs: fatal attraction, but time for intervention
Monaldi Archives for Chest Disease, 2005 -
J.C. Winck, M. Gonçalves
doaj +1 more source
Breathe, 2023 Pulmonary functional imaging modalities such as computed tomography, magnetic resonance imaging and nuclear imaging can quantitatively assess regional lung functional parameters and their distributions. These include ventilation, perfusion, gas exchange at the microvascular level and biomechanical properties, among other variables.
Sam Bayat, Jim Wild, Tilo Winkler
openaire +2 more sources
Investigational Treatments in Phase I and II Clinical Trials: A Systematic Review in Asthma
Biomedicines, 2022 Inhaled corticosteroids (ICS) remain the mainstay of asthma treatment, along with bronchodilators serving as control agents in combination with ICS or reliever therapy.
Luigino Calzetta +6 more
doaj +1 more source
Clinical manifestations of a new alpha‐1 antitrypsin genetic variant: Q0parma
Respirology Case Reports, 2022 Alpha‐1 antitrypsin deficiency is an autosomal, codominant disorder caused by mutations of the SERPINA1 gene. Several mutations of SERPINA1 have been described associated with the development of pulmonary emphysema and/or chronic liver disease and ...
Marina Aiello +9 more
doaj +1 more source
Cells, 2022 COPD is an incurable disorder, characterized by a progressive alveolar tissue destruction and defective mechanisms of repair and defense leading to emphysema.
Luigino Calzetta +6 more
doaj +1 more source
Pharmaceutics, 2022 Despite females being more often affected by asthma than males and the prevalence of COPD rising in females, conflicting evidence exists as to whether sex may modulate the correct inhaler technique.
Luigino Calzetta +6 more
doaj +1 more source
Improving spirometry testing by understanding patient preferences
ERJ Open Research, 2021 The American Thoracic Society and European Respiratory Society commissioned a task force to update the technical standards for spirometry testing with the aim of increasing the accuracy, precision and quality of spirometry measurements and improving the ...
Barbara Johnson +3 more
doaj +1 more source
Caveolins and Lung Function [PDF]
, 2012 The primary function of the mammalian lung is to facilitate diffusion of oxygen to venous blood and to ventilate carbon dioxide produced by catabolic reactions within cells. However, it is also responsible for a variety of other important functions, including host defense and production of vasoactive agents to regulate not only systemic blood pressure,
Olga Chernaya +3 more
openaire +3 more sources