Results 21 to 30 of about 1,734,155 (309)
Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung development. [PDF]
, 2015 BackgroundAdenomatous polyposis coli (Apc) is a tumor suppressor that inhibits Wnt/Ctnnb1. Mutations of Apc will not only lead to familial adenomatous polyposis with associated epithelial lesions, but will also cause aggressive fibromatosis in ...
Bellusci, Saverio +9 more
core +1 more source
Functional imaging in lung cancer [PDF]
Clinical Physiology and Functional Imaging, 2013 SummaryLung cancer represents an increasingly frequent cancer diagnosis worldwide. An increasing awareness on smoking cessation as an important mean to reduce lung cancer incidence and mortality, an increasing number of therapy options and a steady focus on early diagnosis and adequate staging have resulted in a modestly improved survival.
Harders, S. W. +2 more
openaire +4 more sources
Spirometry in fuel station attendants : a comparative study [PDF]
, 2015 Exposure to volatile fuel compounds and roadway motor vehicle exhaust leads to increased risk of chronic lung disease and carcinogenesis. Tobacco smoking further accelerates this process. Spirometry is an objective way of assessing lung function. The aim
Borg, Manwel, Vella, Jacob
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HTR4 gene structure and altered expression in the developing lung [PDF]
, 2013 Background: Meta-analyses of genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) spanning the 5-hydroxytryptamine receptor 4 (5-HT4R) gene (HTR4) associated with lung function.
Billington, CK +11 more
core +2 more sources
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Lung function decline in COPD [PDF]
International Journal of Chronic Obstructive Pulmonary Disease, 2012 The landmark study of Fletcher and Peto on the natural history of tobacco smoke-related chronic airflow obstruction suggested that decline in the forced expiratory volume in the first second (FEV(1)) in chronic obstructive pulmonary disease (COPD) is slow at the beginning, becoming faster with more advanced disease.
Claudio Tantucci, Denise Modina
openaire +5 more sources
Absolute electrical impedance tomography (aEIT) guided ventilation therapy in critical care patients: simulations and future trends [PDF]
, 2010 Thoracic electrical impedance tomography (EIT) is a noninvasive, radiation-free monitoring technique whose aim is to reconstruct a cross-sectional image of the internal spatial distribution of conductivity from electrical measurements made by injecting ...
Brown, B.H. +5 more
core +2 more sources
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Functional vascularized lung grafts for lung bioengineering [PDF]
Science Advances, 2017 We propose a new approach to lung regeneration by replacement of damaged epithelium with full preservation of lung vasculature.
N. Valerio Dorrello +12 more
openaire +4 more sources
Genes and Pathways Regulating Decline in Lung Function and Airway Remodeling in Asthma. [PDF]
, 2019 Asthma is a common disorder of the airways characterized by airway inflammation and by decline in lung function and airway remodeling in a subset of asthmatics.
Broide, David H, Hur, Gyu Young
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