Results 1 to 10 of about 1,342,158 (290)

Oxidative Stress and Inflammation in Acute and Chronic Lung Injuries [PDF]

Antioxidants, 2023
Acute and chronic lung injuries are among the leading causes of mortality worldwide. Lung injury can affect several components of the respiratory system, including the airways, parenchyma, and pulmonary vasculature.
Frank Silva Bezerra, Manuella Lanzetti, Renata Tiscoski Nesi, Akinori Cardozo Nagato, Cyntia Pecli e Silva, Emanuel Kennedy-Feitosa, Adriana Correa Melo, Isabella Cattani-Cavalieri, Luís Cristóvão Porto, Samuel Santos Valenca   +9 more
doaj   +3 more sources

Protective Role of Octreotide in Acute and Chronic Lung Injuries [PDF]

International Journal of Preventive Medicine
Background: The treatment of acute respiratory distress syndrome (ARDS) has been the prominent concern in the clinic. Special attentions have been made to investigate the pathophysiological and pharmacological aspects of acute and chronic lung injuries ...
Ghasem Zarei, Zahra Pezeshki, Samira Choopani, Behnoush Mohammadi, Ardeshir Talebi, Mehdi Nematbakhsh   +5 more
doaj   +2 more sources

Single-cell transcriptomics reveals immune dysregulation mediated by IL-17A in initiation of chronic lung injuries upon real-ambient particulate matter exposure [PDF]

Particle and Fibre Toxicology, 2022
Background Long-term exposure to fine particulate matter (PM2.5) increases susceptibility to chronic respiratory diseases, including inflammation and interstitial fibrosis.
Rui Zhang, Shen Chen, Liping Chen, Lizhu Ye, Yue Jiang, Hui Peng, Zhanyu Guo, Miao Li, Xinhang Jiang, Ping Guo, Dianke Yu, Rong Zhang, Yujie Niu, Yuan Zhuang, Michael Aschner, Yuxin Zheng, Daochuan Li, Wen Chen   +17 more
doaj   +2 more sources

Protective effects of emodin on lung injuries in rat models of liver fibrosis [PDF]

Open Life Sciences, 2019
The aim of this study is to investigate the protective effects of emodin (EMD) on the lung injuries in the rat models of liver fibrosis.
Zhang Lili, Zhang Huiying, Wang Limin, Fan Yimin, Zhang Cuiying, Li Xujiong, Han Dewu, Ji Cheng   +7 more
doaj   +2 more sources

Melittin Exerts Beneficial Effects on Paraquat-Induced Lung Injuries in Mice by Modifying Oxidative Stress and Apoptosis [PDF]

Molecules, 2019
Melittin (MEL) is a 26-amino acid peptide with numerous biological activities. Paraquat (PQ) is one of the most widely used herbicides, although it is extremely toxic to humans.
Bishoy El-Aarag, Mohamed Magdy, Mohamed F. AlAjmi, Shaden A.M. Khalifa, Hesham R. El-Seedi   +4 more
doaj   +2 more sources

Norepinephrine Leads to More Cardiopulmonary Toxicities than Epinephrine by Catecholamine Overdose in Rats

Toxics, 2020
While catecholamines like epinephrine (E) and norepinephrine (NE) are commonly used in emergency medicine, limited studies have discussed the harm of exogenously induced catecholamine overdose.
Wen-Hsien Lu, Hsin-Hung Chen, Bo-Hau Chen, Jui-Chen Lee, Chi-Cheng Lai, Che-Hsing Li, Ching-Jiunn Tseng   +6 more
doaj   +1 more source

Can Stem Cells Beat COVID-19: Advancing Stem Cells and Extracellular Vesicles Toward Mainstream Medicine for Lung Injuries Associated With SARS-CoV-2 Infections

Frontiers in Bioengineering and Biotechnology, 2020
A number of medicines are currently under investigation for the treatment of COVID-19 disease including anti-viral, anti-malarial, and anti-inflammatory agents.
Wojciech Chrzanowski, Sally Yunsun Kim, Lana McClements   +2 more
doaj   +1 more source

Wilms’ tumour gene 1 (WT1) enhances non-small cell lung cancer malignancy and is inhibited by microRNA-498-5p

BMC Cancer, 2023
Background Wilms’ tumour gene 1 (WT1) is clearly recognized as a tumour promoter in diversiform of human malignancies. Nevertheless, knowledge of its expression, functions and potential molecular mechanisms in non-small cell lung cancer (NSCLC) remains ...
Xuebing Li, Wenzhe An, Hongli Pan, Yaguang Fan, Hua Huang, Yixuan Wang, Wang Shen, Lingling Zu, Fanrong Meng, Xuexia Zhou   +9 more
doaj   +1 more source

Intratracheal transplantation of mesenchymal stem cells attenuates hyperoxia-induced lung injury by down-regulating, but not direct inhibiting formyl peptide receptor 1 in the newborn mice. [PDF]

PLoS ONE, 2018
Formyl peptide receptor 1 (FPR1) has been shown to be a key regulator of inflammation. However, its role in bronchopulmonary dysplasia (BPD) has not been delineated yet.
Young Eun Kim, Won Soon Park, So Yoon Ahn, Dong Kyung Sung, Yun Sil Chang   +4 more
doaj   +1 more source

Spinal fractures and/or spinal cord injuries are associated with orthopedic and internal organ injuries in proximity to the spinal injury

North American Spine Society Journal, 2021
Background: the demographics, mechanisms of injury, and concurrent injuries associated with cervical, thoracic and lumbar spinal fracture and/or spinal cord injury remain poorly characterized.
Nidharshan S. Anandasivam, Nathaniel T. Ondeck, Paul S. Bagi, Anoop R. Galivanche, Andre M. Samuel, Daniel D. Bohl, Jonathan N. Grauer   +6 more
doaj   +1 more source