Results 31 to 40 of about 877,566 (357)

Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury

Cell Death and Disease, 2023
Macrophage/microglia polarization acts as an important part in regulating inflammatory responses in spinal cord injury (SCI). However, the regulation of inflammation of Schwann cell-derived exosomes (SCDEs) for SCI repair is still unclear.
Jie Ren, Bin Zhu, Guangjin Gu, Wencan Zhang, Junjin Li, Hongda Wang, Min Wang, Xiaomeng Song, Zhijian Wei, Shiqing Feng   +9 more
doaj   +1 more source

Simvastatin decreases the level of heparin-binding protein in patients with acute lung injury [PDF]

, 2013
Background: Heparin-binding protein is released by neutrophils during inflammation and disrupts the integrity of the alveolar and capillary endothelial barrier implicated in the development of acute lung injury and systemic organ failure.
A Linder, Cecilia M O’Kane, Daniel F McAuley, DF McAuley, DG Sinclair, G Weitz-Schmidt, H Herwald, H Sengelov, H Tapper, Heiko Herwald, J Grommes, JR Jacobson, K Tsushima, Karim Dib, KP Steinberg, M Shyamsundar, MB Fessler, MS Chew, MS Diamond, Murali Shyamsundar, N Gautam, O Soehnlein, O Soehnlein, S Steiner, S Zhang, Thelma R Craig, TR Craig, WM Shafer   +27 more
core   +1 more source

Hypoxia-Inducible Factor Signaling in Inflammatory Lung Injury and Repair

Cells, 2022
Inflammatory lung injury is characterized by lung endothelial cell (LEC) death, alveolar epithelial cell (AEC) death, LEC–LEC junction weakening, and leukocyte infiltration, which together disrupt nutrient and oxygen transport.
Colin E. Evans
doaj   +1 more source

Ang-(1–7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization

Cell & Bioscience, 2023
Background Inflammatory response is an essential part of secondary injury after spinal cord injury (SCI). During this period, the injury may be exacerbated through the release of a large number of inflammatory factors and the polarization of infiltrating
Guangjin Gu, Bin Zhu, Jie Ren, Xiaomeng Song, Baoyou Fan, Han Ding, Jun Shang, Heng Wu, Junjin Li, Hongda Wang, Jinze Li, Zhijian Wei, Shiqing Feng   +12 more
doaj   +1 more source

Use of airway pressure-based indices to detect high and low inspiratory effort during pressure support ventilation: a diagnostic accuracy study

Annals of Intensive Care, 2023
Background Assessment of the patient’s respiratory effort is essential during assisted ventilation. We aimed to evaluate the accuracy of airway pressure (P aw)-based indices to detect potential injurious inspiratory effort during pressure support (PS ...
Yan-Lin Yang, Yang Liu, Ran Gao, De-Jing Song, Yi-Min Zhou, Ming-Yue Miao, Wei Chen, Shu-Peng Wang, Yue-Fu Wang, Linlin Zhang, Jian-Xin Zhou   +10 more
doaj   +1 more source

Improvement of lung preservation - From experiment to clinical practice [PDF]

, 2002
Background. Reperfusion injury represents a severe early complication following lung transplantation. Among the pathogenetic factors, the high potassium content of Euro-Collins(R) solution is discussed.
Bittmann, I., Fürst, H., Hatz, Rudolf A., Kellner, B., Müller, Ch., Reichart, B., Schelling, G., Schildberg, Friedrich Wilhelm   +7 more
core   +1 more source

Acute lung injury

, 2018
A wide variety of insults can produce acute lung damage, inclusive of those that injure the lungs directly. The clinical syndrome of acute onset respiratory distress, dyspnea, and bilateral infiltrates is referred to as acute respiratory distress syndrome.
Cheung O. -Y., Graziano P., Smith M. L.
openaire   +2 more sources

Glycolysis and acute lung injury: A review

Asian Pacific Journal of Tropical Medicine, 2023
Acute lung injury is featured as diffuse pulmonary edema and persistent hypoxemia caused by lung or systemic injury. It is believed that these pathological changes are associated with damage to the alveolar epithelium and vascular endothelium ...
Yang Yi, Jun Chen, Nan Li, Yue Huang, Jichao Peng, Xiaoran Liu   +5 more
doaj   +1 more source

Lung Cancer in Pulmonary Fibrosis: Tales of Epithelial Cell Plasticity [PDF]

, 2011
Lung epithelial cells exhibit a high degree of plasticity. Alterations to lung epithelial cell function are critically involved in several chronic lung diseases such as pulmonary fibrosis.
Adamson IY, Artinian V, Aubry MC, Bai JW, Baumgartner KB, Berschneider B, Brody AR, Chen PP, Chilosi M, Chilosi M, Coalson JJ, Corrin B, Dasari V, Dissanayake SK, Dobbs LG, Flozak AS, Fukuda Y, Ha HY, Haddad R, Herzog EL, Hironaka M, Hu J, Huang CL, Hubbard R, Huber MA, Jayachandran A, Kasai H, Kasper M, Kato N, Kawasaki H, Kawasaki H, Kim J, Kim K, Kim KK, Kuwano K, Königshoff M, Königshoff M, Königshoff M, Lee JM, Liu L, Maher TM, Margalit O, Mason RJ, Matthay MA, Mazieres J, Melanie Königshoff, Moon RT, Nagai A, Pan LH, Park J, Pennison M, Plataki M, Qunn L, Radisky DC, Rosas IO, Sato M, Selman M, Selman M, Soon LL, Sternlicht MD, Thannickal VJ, Thiery JP, Uematsu K, Willis BC, Willis BC, Willis BC, Zavadil J   +66 more
core   +1 more source

Microarray meta-analysis identifies acute lung injury biomarkers in donor lungs that predict development of primary graft failure in recipients. [PDF]

PLoS ONE, 2012
To perform a meta-analysis of gene expression microarray data from animal studies of lung injury, and to identify an injury-specific gene expression signature capable of predicting the development of lung injury in humans.We performed a microarray meta ...
Pingzhao Hu, Xinchen Wang, Jack J Haitsma, Suleiman Furmli, Hussain Masoom, Mingyao Liu, Yumiko Imai, Arthur S Slutsky, Joseph Beyene, Celia M T Greenwood, Claudia dos Santos   +10 more
doaj   +1 more source