Results 21 to 30 of about 494,720 (246)

Phagocytosis is a primary determinant of pulmonary clearance of clinical Klebsiella pneumoniae isolates

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionKlebsiella pneumoniae (Kp) is a common cause of hospital-acquired pneumonia. Although previous studies have suggested that evasion of phagocytic uptake is a virulence determinant of Kp, few studies have examined phagocytosis sensitivity in ...
Rick van der Geest, Hongye Fan, Hernán F. Peñaloza, William G. Bain, William G. Bain, Zeyu Xiong, Naina Kohli, Emily Larson, Mara L. G. Sullivan, Jonathan M. Franks, Donna B. Stolz, Ryota Ito, Kong Chen, Yohei Doi, Yohei Doi, Melanie J. Harriff, Melanie J. Harriff, Janet S. Lee, Janet S. Lee, Janet S. Lee   +19 more
doaj   +1 more source

The role of ubiquitination and deubiquitination in the regulation of cell junctions

Protein & Cell, 2017
Maintenance of cell junctions plays a crucial role in the regulation of cellular functions including cell proliferation, permeability, and cell death.
Junting Cai, Miranda K. Culley, Yutong Zhao, Jing Zhao   +3 more
doaj   +1 more source

Acute lung injury

, 2018
A wide variety of insults can produce acute lung damage, inclusive of those that injure the lungs directly. The clinical syndrome of acute onset respiratory distress, dyspnea, and bilateral infiltrates is referred to as acute respiratory distress syndrome.
Cheung O. -Y., Graziano P., Smith M. L.
openaire   +2 more sources

Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury

Cell Death and Disease, 2023
Macrophage/microglia polarization acts as an important part in regulating inflammatory responses in spinal cord injury (SCI). However, the regulation of inflammation of Schwann cell-derived exosomes (SCDEs) for SCI repair is still unclear.
Jie Ren, Bin Zhu, Guangjin Gu, Wencan Zhang, Junjin Li, Hongda Wang, Min Wang, Xiaomeng Song, Zhijian Wei, Shiqing Feng   +9 more
doaj   +1 more source

Ang-(1–7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization

Cell & Bioscience, 2023
Background Inflammatory response is an essential part of secondary injury after spinal cord injury (SCI). During this period, the injury may be exacerbated through the release of a large number of inflammatory factors and the polarization of infiltrating
Guangjin Gu, Bin Zhu, Jie Ren, Xiaomeng Song, Baoyou Fan, Han Ding, Jun Shang, Heng Wu, Junjin Li, Hongda Wang, Jinze Li, Zhijian Wei, Shiqing Feng   +12 more
doaj   +1 more source

Hypoxia-Inducible Factor Signaling in Inflammatory Lung Injury and Repair

Cells, 2022
Inflammatory lung injury is characterized by lung endothelial cell (LEC) death, alveolar epithelial cell (AEC) death, LEC–LEC junction weakening, and leukocyte infiltration, which together disrupt nutrient and oxygen transport.
Colin E. Evans
doaj   +1 more source

Consensus Standards and Recommendations for Developmental and Cognitive Surveillance, Screening, and Evaluation in Sickle Cell Disease: Executive Summary From the National Alliance of Sickle Cell Centers Neurocognitive Workgroup

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurodevelopmental and neurocognitive difficulties are prevalent among individuals with sickle cell disease and warrant prompt identification and support. This Special Report provides an executive summary of standards and recommendations for surveillance, screening, and evaluation for development and cognition across the lifespan developed by ...
Alyssa M. Schlenz, Donna Murdaugh, Andrew M. Heitzer, Jennifer N. Longoria, Wendy Santos‐Modesitt, Arianna Martin, Judy Cavazos, Jeff Schatz, Catherine R. Hoyt, Alison King, Eboni I. Lance, Steven Hardy, Marsha Treadwell   +12 more
wiley   +1 more source

Use of airway pressure-based indices to detect high and low inspiratory effort during pressure support ventilation: a diagnostic accuracy study

Annals of Intensive Care, 2023
Background Assessment of the patient’s respiratory effort is essential during assisted ventilation. We aimed to evaluate the accuracy of airway pressure (P aw)-based indices to detect potential injurious inspiratory effort during pressure support (PS ...
Yan-Lin Yang, Yang Liu, Ran Gao, De-Jing Song, Yi-Min Zhou, Ming-Yue Miao, Wei Chen, Shu-Peng Wang, Yue-Fu Wang, Linlin Zhang, Jian-Xin Zhou   +10 more
doaj   +1 more source

Blast injuries of the lungs

Journal of British Surgery, 1976
Abstract Up until 1968 Northern Ireland was a relatively peaceful community. The outbreak of civil disturbance has resulted in many patients being admitted to hospital with severe injuries from bullets and bomb explosions. Initial resuscitation must not be unduly delayed to be effective and should be carried out by experienced personnel.
openaire   +2 more sources

Apoptosis and lung injury

The Keio Journal of Medicine, 2005
Apoptosis is important in developmental biology and in remodeling of tissues during repair. Apoptosis also plays important roles in the progression of many diseases. The cellular and molecular mechanisms of apoptosis, in general, have been extensively demonstrated. However, the causes and the roles of apoptosis of various cell types in the lung are not
Lu, Qing, Harrington, Elizabeth O., Rounds, Sharon   +2 more
openaire   +2 more sources