Results 31 to 40 of about 374,911 (160)

The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future. [PDF]

open access: yes, 2020
The respiratory system, which includes the trachea, airways, and distal alveoli, is a complex multi-cellular organ that intimately links with the cardiovascular system to accomplish gas exchange.
Basil, Maria C   +15 more
core   +2 more sources

Hypertonic saline reduces inflammation and enhances the resolution of oleic acid induced acute lung injury [PDF]

open access: yes, 2008
Background Hypertonic saline (HTS) reduces the severity of lung injury in ischemia-reperfusion, endotoxin-induced and ventilation-induced lung injury. However, the potential for HTS to modulate the resolution of lung injury is not known.
Muiris T Kennedy   +32 more
core   +2 more sources

Adipose-derived stem cells weigh in as novel therapeutics for acute lung injury [PDF]

open access: yes, 2014
Acute lung injury is characterized by intense neutrophilic lung inflammation and increased alveolar-capillary barrier permeability leading to severe hypoxemia, and is associated with high mortality despite improvements in supportive care.
Gupta, Kushagra   +2 more
core   +1 more source

Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury

open access: yesCell Death and Disease, 2023
Macrophage/microglia polarization acts as an important part in regulating inflammatory responses in spinal cord injury (SCI). However, the regulation of inflammation of Schwann cell-derived exosomes (SCDEs) for SCI repair is still unclear.
Jie Ren   +9 more
doaj   +1 more source

protection by adrenomedullin [PDF]

open access: yes, 2014
Ventilator-induced lung injury (VILI) contributes to morbidity and mortality in acute respiratory distress syndrome (ARDS). Particularly pre-injured lungs are susceptible to VILI despite protective ventilation. In a previous study, the endogenous peptide
Gruber, Achim Dieter   +13 more
core   +1 more source

Acute lung injury

open access: yes, 2018
A wide variety of insults can produce acute lung damage, inclusive of those that injure the lungs directly. The clinical syndrome of acute onset respiratory distress, dyspnea, and bilateral infiltrates is referred to as acute respiratory distress syndrome.
Cheung O. -Y., Graziano P., Smith M. L.
openaire   +2 more sources

Optical Imaging of Lipopolysaccharide-induced Oxidative Stress in Acute Lung Injury from Hyperoxia and Sepsis [PDF]

open access: yes, 2013
Reactive oxygen species (ROS) have been implicated in the pathogenesis of many acute and chronic pulmonary disorders such as acute lung injury (ALI) in adults and bronchopulmonary dysplasia (BPD) in premature infants.
Audi, Said H.   +6 more
core   +3 more sources

Ex-vivo recruitment and x-ray assessment of donor lungs in a challenging retrieval from a donor supported by lvad using the portable normothermic perfusion system: A case report [PDF]

open access: yes, 2017
Lung transplantation (LTx) is limited by the shortage of suitable donors. To overcome this problem, many programs have begun to use donors with extended criteria (marginal donors).
Calabrese, Fiorella   +7 more
core   +1 more source

Ang-(1–7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization

open access: yesCell & Bioscience, 2023
Background Inflammatory response is an essential part of secondary injury after spinal cord injury (SCI). During this period, the injury may be exacerbated through the release of a large number of inflammatory factors and the polarization of infiltrating
Guangjin Gu   +12 more
doaj   +1 more source

Hypoxia-Inducible Factor Signaling in Inflammatory Lung Injury and Repair

open access: yesCells, 2022
Inflammatory lung injury is characterized by lung endothelial cell (LEC) death, alveolar epithelial cell (AEC) death, LEC–LEC junction weakening, and leukocyte infiltration, which together disrupt nutrient and oxygen transport.
Colin E. Evans
doaj   +1 more source

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