Effects of Different Lung Lavage Solutions on Lung Injury
Türk Yoğun Bakim Derneği Dergisi, 2011 Aim: Experimental animal studies showed that lactated Ringer solution have beneficial effects over isotonic saline solution (0.9% NaCl) for mucociliar activity and clearance of upper respiratory tract.
Hicran Gündoğdu +3 more
doaj +1 more source
Surfactant alterations and treatment of lung transplant ischemia-reperfusion injury [PDF]
, 2006 This review addresses surfactant alterations and treatment in lung transplant ischemia-reperfusion injury. Lung ischemia-reperfusion injury damages the endogenous surfactant system as a result of the production of reactive oxygen species, proteolytic ...
Bogers, A.J.J.C. (Ad) +3 more
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
PI3K-AKT Signaling via Nrf2 Protects against Hyperoxia-Induced Acute Lung Injury, but Promotes Inflammation Post-Injury Independent of Nrf2 in Mice. [PDF]
PLoS ONE, 2015 Lung epithelial and endothelial cell death accompanied by inflammation contributes to hyperoxia-induced acute lung injury (ALI). Impaired resolution of ALI can promote and/or perpetuate lung pathogenesis, including fibrosis.
Narsa M Reddy +5 more
doaj +1 more source
Nebulized PPARγ agonists: a novel approach to augment neonatal lung maturation and injury repair in rats. [PDF]
, 2014 BackgroundBy stimulating lipofibroblast maturation, parenterally administered peroxisome proliferator-activated receptor γ (PPARγ) agonists promote lung homeostasis and injury repair in the neonatal lung.
Gong, Ming +9 more
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Adipose-derived stem cells weigh in as novel therapeutics for acute lung injury [PDF]
, 2014 Acute lung injury is characterized by intense neutrophilic lung inflammation and increased alveolar-capillary barrier permeability leading to severe hypoxemia, and is associated with high mortality despite improvements in supportive care.
Gupta, Kushagra +2 more
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Plasma mitochondrial DNA levels are associated with acute lung injury and mortality in septic patients [PDF]
, 2021 Jiayu Mao +4 more
openalex +1 more source
Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma
Molecular Oncology, EarlyView.PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga +2 more
wiley +1 more source
Macrophages promote epithelial proliferation following infectious and non-infectious lung injury through a Trefoil factor 2-dependent mechanism. [PDF]
, 2019 Coordinated efforts between macrophages and epithelia are considered essential for wound healing, but the macrophage-derived molecules responsible for repair are poorly defined.
Beers, Michael F +10 more
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Leukocyte sequestration in pulmonary microvessels and lung injury following systemic complement activation in rabbits [PDF]
, 1999 Inflammatory reactions are associated with sequestration of leukocytes in the lung. Complement activation leads to accumulation of leukocytes in alveolar septa and alveoli, to lung edema and hemorrhage.
Goetz, Alwin Eduard +5 more
core +1 more source