Protection by 20-5,14-HEDGE Against Surgically-Induced Ischemia Reperfusion Lung Injury in Rats [PDF]
, 2012 Background We previously reported that the cytochrome P450 product 20-hydroxyeicosatetraenoic acid has prosurvival effects in pulmonary artery endothelial cells and ex vivo pulmonary arteries.
Ali, Irshad +6 more
core +2 more sources
Extracorporeal membrane oxygenation improves survival in a novel 24-hour pig model of severe acute respiratory distress syndrome [PDF]
, 2016 Indexación: Web of Science; Pub Med CentralExtracorporeal membrane oxygenation (ECMO) is increasingly being used to treat severe acute respiratory distress syndrome (ARDS).
Alegría, Leyla +16 more
core
Atelectasis Induced by Thoracotomy Causes Lung Injury during Mechanical Ventilation in Endotoxemic Rats [PDF]
, 2011 Atelectasis can impair arterial oxygenation and decrease lung compliance. However, the effects of atelectasis on endotoxemic lungs during ventilation have not been well studied.
Choi, Won-Il +5 more
core +1 more source
High-molecular-weight hyaluronan – a possible new treatment for sepsis-induced lung injury: a preclinical study in mechanically ventilated rats [PDF]
, 2008 Introduction Mechanical ventilation with even moderate-sized tidal volumes synergistically increases lung injury in sepsis and has been associated with proinflammatory low- molecular-weight hyaluronan production. High-molecular- weight hyaluronan (HMW HA)
Dedaj, Rejmon +10 more
core +2 more sources
Restoring microRNA-499-5p Protects Sepsis-Induced Lung Injury Mice Via Targeting Sox6
Nanoscale Research Letters, 2021 Background MicroRNAs (miRs) are known to participate in sepsis; hence, we aim to discuss the protective effect of miR-499-5p targeting sex-determining region Y-related high-mobility-group box 6 (Sox6) on sepsis-induced lung injury in mice.
Wenjie Zhang +3 more
doaj +1 more source
Monitoring of lung edema by microwave reflectometry during lung ischemia-reperfusion injury in vivo [PDF]
, 2006 It is still unclear whether lung edema can be monitored by microwave reflectometry and whether the measured changes in lung dry matter content (DMC) are accompanied by changes in PaO(2) and in pro-to anti-inflammatory cytokine expression (IFN-gamma and ...
Blades B +30 more
core +1 more source
Value of lung ultrasound score for evaluation of blast lung injury in goats
Chinese Journal of Traumatology, 2020 Purpose: To establish a severe blast lung injury model of goats and investigate the feasibility of lung ultrasonic score in the evaluation of blast lung injury.
Yu-Qi Xue +8 more
doaj +1 more source
Physiological Reports, 2021 To date, existing animal models of the acute respiratory distress syndrome (ARDS) have failed to translate preclinical discoveries into effective pharmacotherapy or diagnostic biomarkers.
Mohamad H. Tiba +12 more
doaj +1 more source
Surfactant alterations and treatment of lung transplant ischemia-reperfusion injury [PDF]
, 2006 This review addresses surfactant alterations and treatment in lung transplant ischemia-reperfusion injury. Lung ischemia-reperfusion injury damages the endogenous surfactant system as a result of the production of reactive oxygen species, proteolytic ...
Bogers, A.J.J.C. (Ad) +3 more
core +1 more source
Optical Imaging of Lipopolysaccharide-induced Oxidative Stress in Acute Lung Injury from Hyperoxia and Sepsis [PDF]
, 2013 Reactive oxygen species (ROS) have been implicated in the pathogenesis of many acute and chronic pulmonary disorders such as acute lung injury (ALI) in adults and bronchopulmonary dysplasia (BPD) in premature infants.
Audi, Said H. +6 more
core +3 more sources