Results 71 to 80 of about 374,911 (160)

Restoring microRNA-499-5p Protects Sepsis-Induced Lung Injury Mice Via Targeting Sox6

Nanoscale Research Letters, 2021
Background MicroRNAs (miRs) are known to participate in sepsis; hence, we aim to discuss the protective effect of miR-499-5p targeting sex-determining region Y-related high-mobility-group box 6 (Sox6) on sepsis-induced lung injury in mice.
Wenjie Zhang, Jing Li, Hui Yao, Tianmin Li   +3 more
doaj   +1 more source

An observational study of Donor Ex Vivo Lung Perfusion in UK lung transplantation: DEVELOP-UK [PDF]

, 2016
Background: Many patients awaiting lung transplantation die before a donor organ becomes available. Ex vivo lung perfusion (EVLP) allows initially unusable donor lungs to be assessed and reconditioned for clinical use.
Andreasson, Andreasson, Anyanwu, Arcasoy, Avlonitis, Avlonitis, Behrendt, Benden, Bjørk, Boffini, Boffini, Botha, Brazier, Briggs, Brown, Bury, Charmaz, Christie, Couraud, Curtis, Cypel, Cypel, Cypel, Cypel, Cypel, Cypel, De Perrot, Department of Health, Entwistle, Fielding, Fischer, Fisher, Fisher, Fisher, Fisher, Fisher, Fisher, Gibbs, Glaser, Great Britain, Haugh, Henriksen, Information Services Division, Ingemansson, International Society for Heart and Lung Transplantation, ISD Scotland, Itano, Jirsch, Joint Formulary Committee, Kaba, Kaneda, Kierans, Korovesi, Krutsinger, Lee, Littlefield, Long, Lowton, Lowton, Machuca, Martins, Mays, Moran, Naef, National Health Service, National Heart Lung and Blood Institute, National Institute for Health and Care Excellence, National Institute for Health Care Excellence, NHS Blood and Transplant, NHS Blood and Transplant, NHS Business Service Authority, Office for National Statistics, Okada, OPTUM, Orens, O’Grady, RAND Health, RAND Health Corporation, Renshaw, Roberts, Royal College of Surgeons, Sage, Sanchez, Sanchez, Schaeffer, Siebert, Steen, Steen, Taylor, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Tikkanen, TransMedics, TransMedics, UK Government Department of Constitutional Affairs, van Enckevort, Wallinder, Ware, Warnecke, Warnecke, Wierup, World Medical Organization, XVIVO Perfusion, Zych   +102 more
core   +4 more sources

Apoptosis in Lung Development and Neonatal Lung Injury [PDF]

Pediatric Research, 2004
A healthy organism maintains an integrated balance between proliferating, differentiating, and dying cells. Some cells are irreplaceable, some cells complete their functions and are then sacrificed, and some cells live a finite lifetime, to be replaced by another generation.
Veronic, Del Riccio, Minke, van Tuyl, Martin, Post   +2 more
openaire   +2 more sources

Value of lung ultrasound score for evaluation of blast lung injury in goats

Chinese Journal of Traumatology, 2020
Purpose: To establish a severe blast lung injury model of goats and investigate the feasibility of lung ultrasonic score in the evaluation of blast lung injury.
Yu-Qi Xue, Chun-Shuang Wu, Hua-Cai Zhang, Juan Du, Jian-Hui Sun, An-Qiang Zhang, Ling Zeng, Mao Zhang, Jian-Xin Jiang   +8 more
doaj   +1 more source

Macrophage-expressed IFN-β contributes to apoptotic alveolar epithelial cell injury in severe influenza virus pneumonia [PDF]

, 2013
Influenza viruses (IV) cause pneumonia in humans with progression to lung failure and fatal outcome. Dysregulated release of cytokines including type I interferons (IFNs) has been attributed a crucial role in immune-mediated pulmonary injury during ...
Bodner, Johannes, Gattenlöhner, Stefan, Gruber, Achim D., Herold, Susanne, Högner, Katrin, Kalinke, Ulrich, Lewe-Schlosser, Peter, Lohmeyer, Juergen, Matrosovich, Mikhail, Pleschka, Stephan, Plog, Stephanie, Seeger, Werner, Walmrath, Hans-Dieter, Wolff, Thorsten   +13 more
core   +4 more sources

Metabolic Interplay in Acute Lung Injury: PARK7 Integrates FADS1/2‐Dependent PUFA Metabolism and H3K14 Lactylation to Attenuate Endothelial Ferroptosis and Dysfunction

Advanced Science
Acute respiratory distress syndrome (ARDS) is a severe clinical condition characterized by widespread inflammation and fluid accumulation in the lungs.
Jian Xu, Yuhan Wang, Weiqi Mao, Tianchang Wei, Yufan Li, Juan Song, Cuiping Zhang, Xiaoyan Chen, Cuicui Chen, Qingyuan Xu, Xu Wu, Yuanlin Song   +11 more
doaj   +1 more source

Leukocyte sequestration in pulmonary microvessels and lung injury following systemic complement activation in rabbits [PDF]

, 1999
Inflammatory reactions are associated with sequestration of leukocytes in the lung. Complement activation leads to accumulation of leukocytes in alveolar septa and alveoli, to lung edema and hemorrhage.
Goetz, Alwin Eduard, Groh, Joachim, Kiefmann, Rainer, Kuebler, Wolfgang M., Kuhnle, Gerhard E. H., Sckell, Axel   +5 more
core   +1 more source

Outcomes after pneumonectomy versus limited lung resection in adults with traumatic lung injury. [PDF]

, 2020
Pneumonectomy after traumatic lung injury (TLI) is associated with shock, increased pulmonary vascular resistance, and eventual right ventricular failure. Historically, trauma pneumonectomy (TP) mortality rates ranged between 53 and 100%.
Doben, Andrew R, Dolich, Matthew, Grigorian, Areg, Gross, Ronald, Homo, Richelle L, Kuza, Catherine M, Lekawa, Michael, Nahmias, Jeffry   +7 more
core  

Viral pathogens and acute lung injury: investigations inspired by the SARS epidemic and the 2009 H1N1 influenza pandemic. [PDF]

, 2013
Acute viral pneumonia is an important cause of acute lung injury (ALI), although not enough is known about the exact incidence of viral infection in ALI.
Hendrickson, Carolyn M, Matthay, Michael A   +1 more
core   +2 more sources

Clinical and ventilator waveforms of Chinese patients during pressure support ventilation

Scientific Data
In the field of critical care medicine, accurate analysis of physiological waveform data is crucial for clinical decision-making. Although existing public databases provide a wealth of physiological waveform data, publicly available ventilator waveform ...
Xiaozhu Liu, Peng Wang, Chenjia Hao, Ming-Yue Miao, Xu An, Shan-Shan Xu, Yuefu Wang, Hong-Liang Li, Zongmei Tian, Jian-Xin Zhou   +9 more
doaj   +1 more source