Results 91 to 100 of about 374,911 (160)

Shape-sensing robotic-assisted bronchoscopy (ss-RAB) for peripheral pulmonary nodules: learning curve and diagnostic performance from an initial multicenter experience in China

Respiratory Research
Background Shape-sensing robotic-assisted bronchoscopy (ssRAB) is an emerging technology in geographies outside the United States in use for complex pulmonary nodule biopsy.
Dan Liu, Chun Li, Fangfang Xie, Xianya Hu, Jingyu Shi, Zilong Liu, Jie Liu, Michael J Simoff, Yuanlin Song, Jiayuan Sun   +9 more
doaj   +1 more source

The virulence trait and genotype distribution amongst the Pseudomonas aeruginosa clinical strains

BMC Microbiology
Background Pseudomonas aeruginosa is notorious for its complex virulence system and rapid adaptive drug resistance. This study aimed to compare the prevalence and genotype distribution of virulence genes in multidrug-sensitive and multidrug-resistant ...
Xiaohuan Wang, Kaijing Gao, Baishen Pan, Beili Wang, Yuanlin Song, Wei Guo   +5 more
doaj   +1 more source

PI3K-AKT Signaling via Nrf2 Protects against Hyperoxia-Induced Acute Lung Injury, but Promotes Inflammation Post-Injury Independent of Nrf2 in Mice.

PLoS ONE, 2015
Lung epithelial and endothelial cell death accompanied by inflammation contributes to hyperoxia-induced acute lung injury (ALI). Impaired resolution of ALI can promote and/or perpetuate lung pathogenesis, including fibrosis.
Narsa M Reddy, Haranatha R Potteti, Suryanarayana Vegiraju, Hsin-Jou Chen, Chandra Mohan Tamatam, Sekhar P Reddy   +5 more
doaj   +1 more source

Acute Respiratory Distress Syndrome: Role of Oleic Acid-Triggered Lung Injury and Inflammation

Mediators of Inflammation, 2015
Lung injury especially acute respiratory distress syndrome (ARDS) can be triggered by diverse stimuli, including fatty acids and microbes. ARDS affects thousands of people worldwide each year, presenting high mortality rate and having an economic impact.
Cassiano Felippe Gonçalves-de-Albuquerque, Adriana Ribeiro Silva, Patrícia Burth, Mauro Velho Castro-Faria, Hugo Caire Castro-Faria-Neto   +4 more
doaj   +1 more source

Airway microbiome dysbiosis in severe pneumonia: metagenomic evidence of pathogen expansion and commensal depletion

European Journal of Medical Research
Background The pulmonary microbiome is increasingly recognized as a key determinant of pneumonia severity, yet its clinical implications remain incompletely understood.
Yuhan Wang, Yao Shen, Jie Shen, Jing Bi, Jian Xu, Tianchang Wei, Ruilan Wang, Xueling Wu, Feng Li, Jianwen Bai, Zhijun Jie, Dongni Hou, Yuanlin Song   +12 more
doaj   +1 more source

Use of pressure muscle index to predict the contribution of patient’s inspiratory effort during pressure support ventilation: a prospective physiological study

Frontiers in Medicine
BackgroundThe successful implementation of assisted ventilation depends on matching the patient’s effort with the ventilator support. Pressure muscle index (PMI), an airway pressure based measurement, has been used as noninvasive monitoring to assess the
Ran Gao, Ran Gao, Jian-Xin Zhou, Yan-Lin Yang, Shan-Shan Xu, Yi-Min Zhou, Linlin Zhang, Ming-Yue Miao   +7 more
doaj   +1 more source

Single-cell multiomics analysis reveals CTCF as a key regulator of lung morphogenesis and progenitor maintenance

Nature Communications
Lung development generates a complex tree-like architecture through proximal-distal patterning and branching morphogenesis. However, the gene regulatory programs governing embryonic lung development remain poorly understood.
Shenfei Sun, Yamei Jiang, Fujing Huang, Wei Wei, Mathias Hochgerner, Tianmin Xu, Xiaoting Wang, Kaijun Lin, Xinna Zhang, Yanli Wang, Hua He, Miao Yu, Xiaofang Tang, Xinhua Lin   +13 more
doaj   +1 more source

Vascular Injury After Whole Thoracic X-Ray Irradiation in the Rat [PDF]

, 2009
Purpose To study vascular injury after whole thoracic irradiation with single sublethal doses of X-rays in the rat and to develop markers that might predict the severity of injury.
Fish, B. L., Ghosh, S. N., Jacobs, Elizabeth R., Medhora, Meetha, Molthen, Robert C., Moulder, John E., Mäder, M., Wu, Q.   +7 more
core   +1 more source

The role of biofilm formation by Pseudomonas aeruginosa in respiratory tract infections and its impact on patient prognosis

European Journal of Medical Research
Background Pseudomonas aeruginosa is a prevalent nosocomial pathogen causing respiratory tract infections, and its biofilm formation poses challenges to treatment and influences prognosis.
Xiaohuan Wang, Kaijing Gao, Shuo Yang, Tongtong Tian, Beili Wang, Yuanlin Song, Wei Guo   +6 more
doaj   +1 more source

Protection by Inhaled Hydrogen Therapy in a Rat Model of Acute Lung Injury can be Tracked \u3cem\u3ein vivo\u3c/em\u3e Using Molecular Imaging [PDF]

, 2017
Inhaled hydrogen gas (H2) provides protection in rat models of human acute lung injury (ALI). We previously reported that biomarker imaging can detect oxidative stress and endothelial cell death in vivo in a rat model of ALI.
Audi, Said H., Camara, Amadou K.S., Clough, Anne V., Jacobs, Elizabeth R., Medhora, Meetha M., Rizzo, Benjamin Michael, Zhang, Xiao, Zhao, Ming   +7 more
core   +1 more source