Results 21 to 30 of about 1,661,313 (246)

Low Tidal Volume Ventilation in Patients without Acute Respiratory Distress Syndrome: A Paradigm Shift in Mechanical Ventilation

Critical Care Research and Practice, 2012
Protective ventilation with low tidal volume has been shown to reduce morbidity and mortality in patients suffering from acute lung injury (ALI) and acute respiratory distress syndrome (ARDS).
Jed Lipes, Azadeh Bojmehrani, Francois Lellouche   +2 more
doaj   +1 more source

Effect of Lung Protective Ventilation Combined With Flurbiprofen Axetil on Immune Function During Thoracoscopic Radical Resection of Lung Cancer

Frontiers in Surgery, 2022
The decreased immune function of patients with lung cancer has always been the focus of clinical attention. However, the stress response caused by surgery, anesthesia and pain will further reduce the body's immune function and affect the prognosis of ...
Jia Yuan, Shenghua Cen, Jingjing Li, Kun Wang, Qixu Chen, Hongbin Li, Yan Zhang   +6 more
doaj   +1 more source

Lung-Protective Ventilation in Neonatology

, 2011
Ventilator-induced lung injury (VILI) is considered an important risk factor in the development of bronchopulmonary dysplasia (BPD) and is primarily caused by overdistension (volutrauma) and repetitive opening and collapse (atelectrauma) of terminal lung
Anton van Kaam
core   +2 more sources

Brain injury after 50 h of lung-protective mechanical ventilation in a preclinical model

Scientific Reports, 2021
Mechanical ventilation is the cornerstone of the Intensive Care Unit. However, it has been associated with many negative consequences. Recently, ventilator-induced brain injury has been reported in rodents under injurious ventilation settings.
Thiago G. Bassi, Elizabeth C. Rohrs, Karl C. Fernandez, Marlena Ornowska, Michelle Nicholas, Matt Gani, Doug Evans, Steven C. Reynolds   +7 more
doaj   +1 more source

Latest insights of lung protective ventilation

, 2014
The targets of mechanical ventilation in ARDS have shifted from providing normal gas exchange to protecting the lung from VILI. The distending force of the lung (the trigger of VILI) is the transpulmonary pressure (PL)—the difference between the airway ...
L. Gattinoni
core   +2 more sources

Protective Ventilation vs. Hypercapnia for the Attenuation of Ventilator-Associated Lung Injury [PDF]

, 2011
Mechanically ventilated patients are at risk of developing Ventilator-Associated Lung Injury (VALI). Improved ventilation strategies by lung-protective settings may cause hypercapnia.
Ismaiel, Nada
core   +2 more sources

Pulmonary stretch receptor activity during partial liquid ventilation in cats with healthy lungs [PDF]

, 2004
Aim: To study whether pulmonary stretch receptor (PSR) activity in mechanically ventilated young cats with healthy lungs during partial liquid ventilation (PLV) is different from that during gas ventilation (GV).
Sedin, G., Sindelar, R., Schulze, A., Rieger-Fackeldey, Esther, Jonzon, A.   +4 more
core   +1 more source

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver

Hepatology, EarlyView., 2022
Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid, Victor Olsavszky, Manuel Reinhart, Vanessa Weyer, Felix A. Trogisch, Carsten Sticht, Manuel Winkler, Sina W. Kürschner, Johannes Hoffmann, Roxana Ola, Theresa Staniczek, Joerg Heineke, Beate K. Straub, Jens Mittler, Kai Schledzewski, Peter ten Dijke, Karsten Richter, Steven Dooley, Cyrill Géraud, Sergij Goerdt, Philipp‐Sebastian Koch   +20 more
wiley   +1 more source

Mechanical power in AVM-2 versus conventional ventilation modes in various ARDS lung models. Bench study

, 2022
Introduction Mechanical power has been linked to ventilator induced lung injury and mortality in acute respiratory distress syndrome (ARDS). Adaptive Ventilator Mode-2 (AVM-2) is a closed-loop pressure-controlled mode with an optimal targeting scheme ...
Yeo, Jihun, Maan Gozun, Jihun Yeo, Claudio Luciano Franck, Shah, Parthav, Daoud, Ehab, Franck, Claudio, Keitoku, Koichi, Parthav Shah, Ehab G. Daoud, Keitoku Koichi   +10 more
core   +1 more source

Ventilation inhomogeneity in patients with cystic fibrosis measured by electrical impedance tomography [PDF]

, 2012
Objective: The distribution of ventilation within the lung is inhomogeneous. We hypothesized that the degree of inhomogeneity in patients with cystic fibrosis (CF) differs from that in healthy subjects.
Zhao, Zhanqi, Mueller-Lisse, Ullrich, Moeller, Knut, Fischer, Rainald   +3 more
core   +1 more source