Discordance Between Patient and Physician Global Assessments in Early Systemic Sclerosis
Objective This study aims to identify factors associated with patient global assessment (PtGA) and physician global assessment (PhGA) and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (<5 years) from the Collaborative National Quality and Efficacy Registry were included.
Ellen Romich +35 more
wiley +1 more source
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang +10 more
wiley +1 more source
We report the case of a 54‐year‐old man with right‐lung pneumonia and contralateral pulmonary embolism (PE) conditioning severe refractory hypoxemia requiring veno‐venous extracorporeal membrane oxygenation. Electrical impedance tomography (EIT) was used
Roberta Garberi +6 more
doaj +1 more source
The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo +9 more
wiley +1 more source
Integrated Bayesian approach to incorporate prior biological knowledge in the investigation of genetic variants associated with lung function [PDF]
Genetic association studies aim to identify single-nucleotide polymorphisms (SNPs) that are associated with complex diseases and traits. These studies, especially those performed at the genome-wide level, have successfully identified many SNPs associated
Pereira, M
core +1 more source
Dynamic hyperinflation and intrinsic positive end-expiratory pressure in ARDS patients
Background In ARDS patients, changes in respiratory mechanical properties and ventilatory settings can cause incomplete lung deflation at end-expiration. Both can promote dynamic hyperinflation and intrinsic positive end-expiratory pressure (PEEP).
Silvia Coppola +6 more
doaj +1 more source
Bedside Assessment of Lung Recruitability: Making Sense of the Recruitment-to-Inflation Ratio. [PDF]
Chatburn RL +4 more
europepmc +1 more source
Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet +11 more
wiley +1 more source
Lung Cancer in Pulmonary Fibrosis: Tales of Epithelial Cell Plasticity [PDF]
Lung epithelial cells exhibit a high degree of plasticity. Alterations to lung epithelial cell function are critically involved in several chronic lung diseases such as pulmonary fibrosis.
Königshoff, M. +2 more
core +1 more source
Future directions of lung‐protective ventilation strategies in acute respiratory distress syndrome
Acute respiratory distress syndrome (ARDS) is characterized by the heterogeneous distribution of lung aeration along a gravitational direction due to increased lung density.
Taiki Hoshino, Takeshi Yoshida
doaj +1 more source

