Results 111 to 120 of about 219,832 (311)

First report of bilateral Bronchial Rheoplasty for treating chronic bronchitis performed in a single procedure

European Clinical Respiratory Journal
Introduction The RheOx system delivers brief, high-voltage electrical pulses to the airway lining, promoting the regeneration of healthy tissue and reducing mucus production in COPD patients with chronic bronchitis.
Kristine Jensen, Erik L. Secher, Regitze H. Libermann, William S. Krimsky, Michael Perch   +4 more
doaj   +1 more source

Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation

Advanced Science, EarlyView.
FT organoids reverse the aged phenotype of tendon cells, reinstating a fetal‐like state. This breakthrough establishes a potent cell source for tendon tissue engineering, effectively advancing regenerative medicine. ABSTRACT Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration ...
Tian Qin, Aini Pan, Zhuoning Miao, Yanyan Zhao, Xianan Mo, Heng Sun, Chunmei Fan, Junyu Guo, Bingbing Wu, Weiliang Shen, Qiangqiang Zheng, Jun Lu, Xi Jiang, Zi Yin, Xiao Chen   +14 more
wiley   +1 more source

Evaluation of computed tomography in the diagnosis of ultrasound-proven diaphragm dysfunction

Respiratory Research
Introduction Computed tomography (CT) is routinely employed on the evaluation of dyspnea, yet limited data exist on its assessment of diaphragmatic muscle.
Pauline Lallement, Alain Boussuges, Paul Habert, Julien Bermudez, Martine Reynaud-Gaubert, Stéphane Delliaux, Fabienne Bregeon, Benjamin Coiffard   +7 more
doaj   +1 more source

Procyanidin Capsules Combat ALF by Restoring Mitochondrial Homeostasis and Inhibiting Necroptosis via the PGAM5/DRP1/PINK1 Pathway

Advanced Science, EarlyView.
A biomimetic self‐assembly strategy, Procyanidin Capsules (PC‐Ca), has been developed, which has great stability, bioavailability, and liver‐targeting efficacy and modulates the KEAP1‐NRF2 axis to inhibit ROS formation and necroptosis, regulate mitochondrial homeostasis through the PGAM5/DRP1/PINK1 signaling pathway in thioacetamide (TAA)‐induced ALF ...
Qing Shi, Minmin Wu, Jinwei Zhong, Chao Chen, Zhuang Huang, Jingxuan Peng, Dong Yang, Xingjie Zan, Zhengfei Wang   +8 more
wiley   +1 more source

Usefulness of monitoring mycophenolic acid exposure in systemic sclerosis-related interstitial lung disease: a retrospective cohort study

BMC Pulmonary Medicine
Background Systemic sclerosis-related interstitial lung disease (SSc-ILD) represents a significant cause of morbidity and mortality in Systemic Sclerosis (SSc). Mycophenolate mofetil (MMF) is currently the first line treatment for SSc-ILD.
Jules Milesi, Emmanuelle Sampol, Audrey Benyamine, Shani Diai, Benjamin Coiffard, Ana Nieves, Brigitte Granel, Martine Reynaud-Gaubert, Julien Bermudez   +8 more
doaj   +1 more source

Long-Term Outcome and the Radiological Evaluation of Lung Growth After Living-Donor Lobar Lung Transplantation in Pediatric Patients [PDF]

, 2022
Satona Tanaka, Y. Morimura, Hidenao Kayawake, Yojiro Yutaka, Yoshito Yamada, A. Ohsumi, Daisuke Nakajima, Masatsugu Hamaji, Hiroshi Date   +8 more
openalex   +1 more source

Safety and Efficacy of Adoptive Transfer of Stem Cell Memory Enriched Virus Specific T Cells against CMV and EBV

Advanced Science, EarlyView.
This study finds that CD8⁺ TSCM cells exhibit superior self‐renewal, differentiation, and antiviral activity. Transcriptome and epigenome analyses highlight MAPK cascade regulation in TSCM cells. In vivo, virus‐specific TSCM cells show enhanced persistence and tumor protection.
Xun‐Hong Cao, Xu‐Ying Pei, Yuan‐Yuan Zhang, Juan Xie, Jing‐Wei Tu, Zhuo‐Jun Liu, Yi‐Yang Ding, Chen‐Hua Yan, Yu‐Hong Chen, Yu Wang, Lan‐Ping Xu, Xiao‐Hui Zhang, Xiao‐Jun Huang, Xiang‐Yu Zhao   +13 more
wiley   +1 more source

(239) CD26/Dipeptidyl Peptidase-4 Inhibitors as Prophylaxis of Chronic Lung Allograft Dysfunction after Lung Transplantation, a Clinicopathological Evaluation [PDF]

, 2023
Y. Yamada, S. Tanaka, Y. Yutaka, M. Hamaji, D. Nakajima, A. Ohsumi, H. Date   +6 more
openalex   +1 more source

Positive Feedback Loop of Histone Lactylation‐Driven HNRNPC Promotes Autophagy to Confer Pancreatic Ductal Adenocarcinoma Gemcitabine Resistance

Advanced Science, EarlyView.
Histone 3 lysine18 lactylation (H3K18la) drives heterogeneous nuclear ribonucleoprotein C (HNRNPC) overexpression, activating autophagy to mediate gemcitabine resistance by stabilizing TNF receptor‐associated factor 6 (TRAF6) mRNA. Concurrently, HNRNPC stabilizes aldehyde dehydrogenase 1 family member A3 (ALDH1A3) mRNA, which enhances glycolysis and ...
Xi‐Tai Huang, Jiao Chen, En‐Liang Zhu, Ming‐Jian Ma, Yang‐Yin‐Hui Yu, Ying‐Qin Zhu, Jing‐Yuan Ye, Jin‐Zhao Xie, Zi‐Yi Zhao, Xiao‐Yu Yin   +9 more
wiley   +1 more source

Identification of novel diagnostic and prognostic microRNAs in sarcoma on TCGA dataset: bioinformatics and machine learning approach

Scientific Reports
The discovery of unique microRNA (miR) patterns and their corresponding genes in sarcoma patients indicates their involvement in cancer development and suggests their potential use in medical management. MiRs were identified from The Cancer Genome Atlas (
Rahem Rahmati, Fatemeh Zarimeidani, Farnaz Ahmadi, Hannaneh Yousefi-Koma, Abdolreza Mohammadnia, Maryam Hajimoradi, Shadi Shafaghi, Elham Nazari   +7 more
doaj   +1 more source