Results 91 to 100 of about 1,460,646 (299)

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Case Report: Low-profile covered stents in CHD: the role of Gore Viabahn (VBX) stents

Frontiers in Pediatrics
The Gore Viabahn covered stent, approved for the treatment of peripheral arterial disease in femoral or iliac artery lesions, may offer advantageous features in the field of congenital heart diseases.
Micol Rebonato, Catarina Almeida, Mara Pilati, Enrico Piccinelli, Gianfranco Butera   +4 more
doaj   +1 more source

Donor lymphocyte count and thymic activity predict lymphocyte recovery and outcomes after matched-sibling hematopoietic stem cell transplant

Haematologica, 2013
Delayed immune recovery is a characteristic feature of allogeneic hematopoietic stem cell transplantation in adult recipients. Although recipient thymic T-cell neogenesis contributes to T-cell regeneration after transplantation, thymic recovery in the ...
Zachariah McIver, Jan Joseph Melenhorst, Colin Wu, Andrew Grim, Sawa Ito, Irene Cho, Nancy Hensel, Minoo Battiwalla, Austin John Barrett   +8 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

New frontiers in lung transplantation : a bioengineering perspective

LTx remains the definitive treatment for end-stage lung disease, but the increasing demand for donor lungs outpaces the available supply. This chapter explores innovative approaches to expand the pool of viable donor lungs and reduce waiting times, which
Lindstedt, Sandra,, Niroomand, Anna,, Perch, Michael,, Lund University., Meloni, Federica,, Lindstedt, Sandra, Niroomand, Anna, Perch, Michael, Meloni, Federica   +8 more
core   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Synchronization‐Dissipation in the Cardiorespiratory System

Advanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border, Alain Nogaret, Andrew Lefevre, Vishal Jain   +3 more
wiley   +1 more source

The role of Diaphram after lung transplannation

, 2018
Lung transplantation is the only treatment for end-stage lung disease in selected patients. Postoperative recovery of ventilatory function may be influenced by several factors, with the diaphragm playing a key role.
A. Lo Mauro, V. Rossetti, I. Righi, A. Palleschi, M. Vergari, D. Tosi, A. Aliverti, E. Privitera, M. Nosotti, C. Colombo, M. Sgroia, D. F. Briganti   +11 more
core   +1 more source

Risk factors for unplanned intensive care unit admission after esophagectomy: a retrospective cohort study of 628 patients with esophageal cancer

Frontiers in Oncology
IntroductionEsophagectomy patients who experience unplanned ICU admission (UIA) may experience a heavier economic burden and worse clinical outcomes than those who experience routine intensive care unit (ICU) admission.
Guoqing Zhang, Shaowu Sun, Zhengxia Dong, Huang Chunyao, Zhulin Wang, Kaiyuan Li, Xu Liu, Yujie Zhang, Junya Wang, Jindong Li, Jia Zhao, Xiangnan Li   +11 more
doaj   +1 more source

Transplantation after ex vivo lung perfusion: A midterm follow-up

, 2016
A large proportion of donor lungs are discarded due to known or presumed organ dysfunction. Ex vivo lung perfusion (EVLP) has proven its value as a tool for discrimination between reversible and irreversible donor lung pathology.
Riise, Gerdt C.,, Ricksten, Sven-Erik,, Dellgren, Göran,, Silverborn, Martin,, Wallinder, Andreas,   +4 more
core   +1 more source