Results 81 to 90 of about 1,460,646 (299)
Charge‐Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti‐Cancer Treatment
Advanced Materials, EarlyView.Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.Renzo A. Knol, Bochuan Hu, Eduard O. Bobylev, Martina Farber, Petrus C. M. Laan, Thomas J. F. Kock, Bauke Fontein, Johanna Erbani, Oscar Escalona‐Rayo, Seline S. Roose, Tom Keijer, Gabriel Forn‐Cuní, B. Ewa Snaar‐Jagalska, Leila Akkari, Joost N. H. Reek, Alexander Kros, Dennis Aschmann +16 morewiley +1 more sourceLung transplantation for cystic fibrosis in Italy
, 2008 Lung transplantation (LT) is the only effective form of therapy for cystic fibrosis (CF) associated with end-stage pulmonary failure. In Italy, the management of CF is regulated by national law, which has instituted regional centers for care and follow ...VENUTA, Federico, BENEDETTI VALENTINI, SARA, M. Rolla, V. D'Alu, A. Bossi, L. Locorriere, S. Benedetti Valentini, V. D’Alu, C. Scacchi, S. Quattrucci, G. Cimino, Italian Group for Lung Transplantation, QUATTRUCCI, Serena, S. Bertasi +13 morecore +1 more sourceA Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration
Advanced Materials Interfaces, EarlyView.The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular Shivani Santosh Sakhrani, Abu ul Hassan S. Rana, S. Sudheer Khan +2 morewiley +1 more sourceAntireflux surgery for prevention of chronic lung allograft dysfunction (CLAD) onset after lung transplantation: The earlier the better before CLAD onset? A single-center series of 284 patients
JHLT OpenBackground: Gastroesophageal reflux disease (GERD) is highly prevalent after lung transplantation (LTx) and is suspected to favor the development of chronic lung allograft dysfunction (CLAD), almost of bronchiolitis obliterans syndrome (BOS) phenotype ...Abdulmonem Hamid, Alexandre Vallée, Sophie Rong, Olivier Boche, Sandra De Miranda, Laurence Beaumont-Azuar, Sylvie Colin de Verdière, Dominique Grenet, Marc Stern, Benjamin Zuber, Jerôme Devaquet, Julien Fessler, Julien De Wolf, Ciprian Pricopi, Matthieu Glorion, Edouard Sage, Jonathan Messika, Antoine Magnan, François Parquin, Clément Picard, Antoine Roux, Olivier Brugière +21 moredoaj +1 more sourceLung and heart-lung transplantation
Cardiology in the Young, 2009 I NCREASED UNDERSTANDING AND AWARENESS OF congenital cardiac disease has allowed early identification of these children. Advances in surgical techniques, anesthesia, and medical treatment have rendered the majority of forms of congenital cardiac defects treatable.Date, Hiroshi, Sweet, Stuart Copenaire +4 more sourcesISHLT consensus statement on the perioperative use of ECLS in lung transplantation : Part II: Intraoperative considerations
The use of extracorporeal life support (ECLS) throughout the perioperative phase of lung transplantation requires nuanced planning and execution by an integrated team of multidisciplinary experts.Cypel, Marcelo, Fessler, Julien, Reed, Anna K.,, Morrissey, Orla,, Dave, Kavita,, Wille, Keith, Lindstedt, Sandra,, Schecter, Marc,, Walsh, James, Nasir, Basil S.,, Wilkey, Barbara J., Dellgren, Göran,, Fessler, Julien,, Gomez-De-Antonio, David, Kukreja, Jasleen,, Cypel, Marcelo,, Lyster, Haifa, Behr, Juergen, Gelzinis, Theresa A., Hoetzenecker, Konrad, Sanchez, Melissa, Landry, Caroline,, Hoetzenecker, Konrad,, Bottiger, Brandi, Sanchez, Melissa,, Behr, Juergen,, Mercier, Olaf,, Marczin, Nandor,, Lund University., Gomez-De-Antonio, David,, Marczin, Nandor, Wille, Keith,, Levvey, Bronwyn, Mercier, Olaf, Fritz, Ashley Virginia,, Wilkey, Barbara J.,, Kukreja, Jasleen, Lindstedt, Sandra, Martin, Archer Kilbourne, Lyster, Haifa,, Schecter, Marc, Dave, Kavita, Nasir, Basil S., Landry, Caroline, Kotecha, Sakhee, Martin, Archer Kilbourne,, Dellgren, Göran, Morrissey, Orla, Saatee, Siavosh, Bottiger, Brandi,, Levvey, Bronwyn,, Kotecha, Sakhee,, Saatee, Siavosh,, Fritz, Ashley Virginia, Reed, Anna K., Walsh, James,, Gelzinis, Theresa A., +56 morecore +1 more sourceLung transplantation for scleroderma lung disease: An international, multicenter, observational cohort study
, 2018 Background: Due to its multisystemic nature, scleroderma is considered a relative contraindication to lung transplantation at many centers. However, recent studies suggest similar post-transplant outcomes in patients with scleroderma compared to those ...Fisher, A. J., Gottlieb, J., Tudorache, Igor, Sandrine Hirschi, Jesper Magnusson, Douvry, B., Borgne, Aurélie Le, Magnusson, Jesper,, Andrew J. Fisher, Jérôme Le Pavec, Savale, L., Laurent Godinas, Brugiere, O., Hirschi, S., Reynaud-Gaubert, M., Knoop, C., Olivier Brugiere, Holm, A. M., Martine Reynaud-Gaubert, Brugiere, Olivier, Magnusson, Jesper, Holm, Are Martin, Are M. Holm, Jens Gottlieb, Schultz, H. H., Hans Henrik Schultz, Gottlieb, Jens, Fisher, Andrew J., Le Pavec, Jérôme, Johanna Claustre, Igor Tudorache, Benoît Douvry, Tudorache, I., Godinas, Laurent, Holm, Are M., Claustre, J., Pradere, P., Pradère, Pauline, Reynaud-Gaubert, Martine, Schultz, Hans Henrik, Fisher, Andrew A.J., Hirschi, Sandrine, Douvry, Benoit, Christiane Knoop, Claustre, Johanna, Le Pavec, J., Le Borgne, A., Lung, Working Grp Heart, Godinas, L., Savale, Laurent, Knoop, Christiane, Aurélie Le Borgne, Le Borgne, Aurelie, Pauline Pradère, Laurent Savale +54 morecore +1 more sourceCoixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma
Advanced Science, EarlyView.Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu +20 morewiley +1 more sourceISHLT Consensus Statement on the Perioperative use of ECLS in Lung Transplantation : Part I: Preoperative Considerations
The use of extracorporeal life support (ECLS) throughout the perioperative phase of lung transplantation requires nuanced planning and execution by an integrated team of multidisciplinary experts.Marczin, Nandor, Cypel, Marcelo, Fessler, Julien, Levvey, Bronwyn, Wille, Keith, Mercier, Olaf, Kukreja, Jasleen, Walsh, James, Lindstedt, Sandra, Wilkey, Barbara J., Martin, Archer Kilbourne, Schecter, Marc, Dave, Kavita, Gomez-De-Antonio, David, Nasir, Basil S., Kotecha, Sakhee, Landry, Caroline, Dellgren, Göran, Morrissey, Orla, Saatee, Siavosh, Behr, Juergen, Lyster, Haifa, Gelzinis, Theresa A., Hoetzenecker, Konrad, Sanchez, Melissa, Bottiger, Brandi, Fritz, Ashley Virginia, Reed, Anna K., Reed, Anna K.,, Dave, Kavita,, Morrissey, Orla,, Schecter, Marc,, Lindstedt, Sandra,, Nasir, Basil S.,, Dellgren, Göran,, Fessler, Julien,, Kukreja, Jasleen,, Cypel, Marcelo,, Landry, Caroline,, Hoetzenecker, Konrad,, Sanchez, Melissa,, Behr, Juergen,, Mercier, Olaf,, Marczin, Nandor,, Lund University., Gomez-De-Antonio, David,, Wille, Keith,, Fritz, Ashley Virginia,, Wilkey, Barbara J.,, Lyster, Haifa,, Martin, Archer Kilbourne,, Bottiger, Brandi,, Kotecha, Sakhee,, Levvey, Bronwyn,, Saatee, Siavosh,, Walsh, James,, Gelzinis, Theresa A., +56 morecore +1 more source