Results 131 to 140 of about 2,645,770 (342)

Microsphere Strategy to Generate Conformal Bone Organoid Units with Osteoimmunomodulation and Sustainable Oxygen Supply for Bone Regeneration

open access: yesAdvanced Science, EarlyView.
Oxygen‐releasing immunomodulatory microspheres are used to construct conformal bone organoid units that enhance osteogenesis, angiogenesis, and immune regulation. By integrating BMSCs, macrophages, and CaO₂‐HAp into a SilMA‐based hydrogel platform, this strategy provides sustained oxygen supply and anti‐inflammatory microenvironments, leading to ...
Anfu Deng   +12 more
wiley   +1 more source

Harnessing the Immunomodulation of UV‐Exposed Keratinocyte Extracellular Vesicles for Inflammatory Disorder Treatment

open access: yesAdvanced Science, EarlyView.
Adopting a paradigm shift that transforms a known health hazard as a potential therapeutic asset, a novel therapeutic strategy is set out to investigate for inflammatory conditions by leveraging immunosuppressive properties of UV‐irradiated keratinocytes.
Lu Liu   +16 more
wiley   +1 more source

Ubiquitination‐Dependent LLGL2 Degradation Drives Colorectal Cancer Progression via THBS3 mRNA Stabilization

open access: yesAdvanced Science, EarlyView.
During the progression of CRC, MDM2, as an E3 ubiquitin ligase, promotes the degradation of the LLGL2 protein. Reduced expression of the LLGL2 protein leads to the loss of support for the CNOT1 protein, decreasing the degradation of THBS3 mRNA. The increased THBS3 further activates the PI3K‐Akt pathway, promoting the proliferation and metastasis of CRC.
Jiayan Huang   +8 more
wiley   +1 more source

Impact of Pulmonary Hypertension on Posttransplant Survival of Patients With Pulmonary Fibrosis at High Altitude: A Prospective Cohort Study

open access: yesCanadian Respiratory Journal
Conclusion: Survival at 1 and 5 years was lower in patients with PH. However, no significant differences in survival were observed based on sex, mPAP, age, or BMI.
Fabio Varón-Vega   +7 more
doaj   +1 more source

Physiologic evaluation of allogeneic canine lung transplants from living donors

open access: bronze, 1969
Eric W. Fonkalsrud   +5 more
openalex   +1 more source

Diaphragm and Lung Transplantation

open access: yesTransplant International
Mutual interactions between the diaphragm and lung transplantation (LTx) are known to exist. Before LTx, many factors can exert notable impact on the diaphragmatic function, such as the underlying respiratory disease, the comorbidities, and the chronic treatments of the patient.
Alessandro Palleschi   +12 more
openaire   +4 more sources

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

open access: yesAdvanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai   +5 more
wiley   +1 more source

Early experience of heart-lung transplantation. [PDF]

open access: bronze, 1989
Rosalind L. Smyth   +7 more
openalex   +1 more source

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