Results 21 to 30 of about 214,416 (313)

The Relationship Between Bacterial Pathogen Presence Detected by Bronchial Lavage and Acute Rejection: 1-Year Follow-up Results Following Lung Transplantation

Haseki Tıp Bülteni, 2022
Aim:Lung transplant recipients are the highest risk group in terms of infective complications among solid organ transplants. It has improved the management of the most common infectious complications with the aid of advances in diagnostic methods ...
Pinar Atagun Guney, Ayse Nigar Halis, Ertan Saribas, Sevinc Citak, Mustafa Vayvada, Murat Ersin Cardak, Yesim Uygun Kizmaz, Ahmet Erdal Tasci   +7 more
doaj   +1 more source

Autologous pericardium used for reconstruction of left innominate vein in patient with mediastinal venous aneurysm:a case report

BMC Surgery, 2020
Background Mediastinal venous aneurysm is a very rare disease and can be easily misdiagnosed. Patients are often asymptomatic while venous aneurysm of large size with adjacent structures oppressed can lead to discomfort.
Cheng Fang, Hui Pan, Zhoubin Li, Liang Ma, Weili Han   +4 more
doaj   +1 more source

High-affinity CD16 integration into a CRISPR/Cas9-edited CD38 locus augments CD38-directed antitumor activity of primary human natural killer cells

Journal for ImmunoTherapy of Cancer, 2022
Background Adoptive transfer of natural killer (NK) cells with augmented antibody-dependent cellular cytotoxicity (ADCC) capabilities and resistance to CD38 targeting has the potential to enhance the clinical anti-myeloma activity of daratumumab (DARA ...
Long Chen, Richard Childs, Robert Reger, Mala Chakraborty, Joseph Andrew Clara, Emily R Levy, Stefan Barisic, Elena Cherkasova, David S J Allan   +8 more
doaj   +1 more source

Advances in Lung Transplantation

Cells, 2023
Nowadays, lung transplantation is a clinical reality for the treatment of benign end-stage respiratory diseases [...]
Davide Tosi, Alessandro Palleschi
openaire   +3 more sources

Annual Report of the Indian Society for Heart and Lung Transplantation Registry 2024 (INTRAN)

Journal of the Practice of Cardiovascular Sciences
This is a registry report of the Indian Society for Heart and Lung Transplantation. The data reflects thoracic transplants done in India since 1994. It is a voluntary cloud-based registry.
Indian Society for Heart and Lung Transplantation (INSHLT)
doaj   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Facilitators and barriers in the donor family interview process from the perspective of hospital staff: a cross-sectional study

Korean Journal of Transplantation, 2023
Background : Obtaining consent from potential donor families is a challenging step in the donation process and is influenced by various factors.
Seyed Mohammad Reza Nejatollahi, Yazdan Abdolmohammadi, Sepideh Ahmadi, Arman Hasanzade, Fatemeh Hosseini, Arshia Mohseni, Shadi Shafaghi, Mojtaba Mokhber Dezfuli, Fariba Ghorbani   +8 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source