Results 41 to 50 of about 1,371,833 (300)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Post‐RSV Bronchial Web Formation in a Lung Transplant Recipient: A Case Report
Respirology Case ReportsBronchial webs (BW) are fibrinous membranes which obstruct the airway lumen. A 33‐year‐old female presented with acute lung allograft dysfunction following a recent respiratory syncytial virus (RSV) infection, having undergone bilateral lung transplant 2
Nathan Harb +5 more
doaj +1 more source
F1000Prime Reports, 2013 Lung transplantation may be the only intervention that can prolong survival and improve quality of life for those individuals with advanced lung disease who are acceptable candidates for the procedure. However, these candidates may be extremely ill and require ventilator and/or circulatory support as a bridge to transplantation, and lung ...
openaire +2 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Case Reports in PulmonologyAspergillus niger and Aspergillus calidoustus are relatively uncommon pathogens that could cause invasive disease, especially in immunocompromised patients. We present the case of a 61-year-old male with a history of idiopathic pulmonary fibrosis who was
Carlos Enrique Calvache Benavides +4 more
doaj +1 more source
Swallowing and laryngeal complications in lung and heart transplantation: Etiologies and diagnosis. [PDF]
, 2022 Despite continued surgical advancements in the field of cardiothoracic transplantation, post-operative complications remain a burden for the patient and the multidisciplinary team.
Madill, C +5 more
core +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Lung transplantation from donors after previous cardiac surgery: ideal graft in marginal donor?
, 2016 Lung transplantation has clearly become the definitive therapeutic option for patient with end-stage lung disease but the number of available donor currently limits this option.
P. Mendogni +8 more
core +2 more sources
Primary lung adenocarcinoma in transplanted lung in post bilateral lung transplantation
Clinical Case Reports, 2023 Key Clinical MessagePrimary lung cancer was reported by a bilateral lung transplant patient without any risk factors. Single lung transplantation should be contemplated instead of double lung transplantation as it has been shown to increase the risk of lung cancers.AbstractThis is a case report of a 37‐year‐old woman, with no history of smoking, who ...
Fathima Shafra Mubarak +2 more
openaire +3 more sources
How small is too small? A systematic review of center volume and outcome after cardiac transplantation [PDF]
, 2012 Background—The aim of this study was to assess the relationship between the volume of cardiac transplantation procedures performed in a center and the outcome after cardiac transplantation.
Hawkins, N.M. +6 more
core +1 more source