Results 31 to 40 of about 1,371,833 (300)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

A real-world experience of transition to robotic-assisted thoracic surgery (RATS) for lung resections

Frontiers in Surgery, 2023
ObjectiveWe report our experience of transition to robotic-assisted thoracic surgery (RATS) for lung resections with the da Vinci Xi surgical system, exposing short-term results.Materials and methodsThis is a single-center, retrospective analysis of RATS
Alessandro Palleschi, Giovanni Mattioni, Giovanni Mattioni, Paolo Mendogni, Davide Tosi   +4 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The utility of a pleural carcinomatosis score for assessing resectability

Pleura and Peritoneum
Malignant pleural effusion is a common evolution of various cancers and is associated with poor prognosis and quality of life. Currently, the surgical approach is mainly palliative, involving videothoracoscopic talc pleurodesis or the insertion of ...
Drevet Gabrielle, Belaroussi Yaniss, Soldea Valentin, Kovacs Erik, Grima Renaud, Maury Jean-Michel, Tronc François   +6 more
doaj   +1 more source

Annual Report of the Indian Society for Heart and Lung Transplantation Registry 2024 (INTRAN)

Journal of the Practice of Cardiovascular Sciences
This is a registry report of the Indian Society for Heart and Lung Transplantation. The data reflects thoracic transplants done in India since 1994. It is a voluntary cloud-based registry.
Indian Society for Heart and Lung Transplantation (INSHLT)
doaj   +1 more source

The Relationship Between Bacterial Pathogen Presence Detected by Bronchial Lavage and Acute Rejection: 1-Year Follow-up Results Following Lung Transplantation

Haseki Tıp Bülteni, 2022
Aim:Lung transplant recipients are the highest risk group in terms of infective complications among solid organ transplants. It has improved the management of the most common infectious complications with the aid of advances in diagnostic methods ...
Pinar Atagun Guney, Ayse Nigar Halis, Ertan Saribas, Sevinc Citak, Mustafa Vayvada, Murat Ersin Cardak, Yesim Uygun Kizmaz, Ahmet Erdal Tasci   +7 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Survival benefit of lung transplantation in individuals with severe α(1)-anti-trypsin deficiency (PiZZ) and emphysema

, 2011
BACKGROUND: The objective of lung transplantation (LTx) is to prolong life, but the survival benefit for patients with severe α(1)-anti-trypsin deficiency (PiZZ) and emphysema is still unclear.
Riise, Gerdt C, Nilsson, Peter,, Hansson, Lennart,, Piitulainen, Eeva,, Tanash, Hanan,, Lund University.   +5 more
core   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Autologous pericardium used for reconstruction of left innominate vein in patient with mediastinal venous aneurysm:a case report

BMC Surgery, 2020
Background Mediastinal venous aneurysm is a very rare disease and can be easily misdiagnosed. Patients are often asymptomatic while venous aneurysm of large size with adjacent structures oppressed can lead to discomfort.
Cheng Fang, Hui Pan, Zhoubin Li, Liang Ma, Weili Han   +4 more
doaj   +1 more source