Results 41 to 50 of about 374,691 (355)

Epidemiology of Cryptococcosis and Cryptococcal Meningitis in a large retrospective cohort of patients after solid organ transplantation [PDF]

, 2017
Background Cryptococcosis is the third most common invasive fungal infection in solid organ transplant (SOT) recipients. There are no nationally representative data describing the incidence, risk factors, and outcomes of cryptococcosis ...
George, Ige A, Olsen, Margaret A, Powderly, William G, Santos, Carlos A   +3 more
core   +2 more sources

Factors influencing transfusion-associated HLA sensitization in patients bridged to heart transplantation using ventricular assist device. [PDF]

, 2020
BackgroundBridging heart failure patients with mechanical ventricular assist devices (VAD) enables access to transplantation. However, VAD is associated with increased risk for anti-HLA antibodies associated with rejection of subsequent allografts ...
Adler, Eric, Elkind, Jae, Morris, Gerald P, Ostberg-Braun, Oscar, Silva Enciso, Jorge, Sobczyk, Juliana   +5 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Post‐RSV Bronchial Web Formation in a Lung Transplant Recipient: A Case Report

Respirology Case Reports
Bronchial webs (BW) are fibrinous membranes which obstruct the airway lumen. A 33‐year‐old female presented with acute lung allograft dysfunction following a recent respiratory syncytial virus (RSV) infection, having undergone bilateral lung transplant 2 
Nathan Harb, Alexander Mullin, Celeste Mar, Rebecca Pearson, Adrian Havryk, Marshall Plit   +5 more
doaj   +1 more source

Lung transplantation [PDF]

F1000Prime Reports, 2013
Lung transplantation may be the only intervention that can prolong survival and improve quality of life for those individuals with advanced lung disease who are acceptable candidates for the procedure. However, these candidates may be extremely ill and require ventilator and/or circulatory support as a bridge to transplantation, and lung ...
openaire   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Facilitators and barriers in the donor family interview process from the perspective of hospital staff: a cross-sectional study

Korean Journal of Transplantation, 2023
Background : Obtaining consent from potential donor families is a challenging step in the donation process and is influenced by various factors.
Seyed Mohammad Reza Nejatollahi, Yazdan Abdolmohammadi, Sepideh Ahmadi, Arman Hasanzade, Fatemeh Hosseini, Arshia Mohseni, Shadi Shafaghi, Mojtaba Mokhber Dezfuli, Fariba Ghorbani   +8 more
doaj   +1 more source

Cost-effectiveness of lung transplantation in The Netherlands: a scenario analysis [PDF]

, 1998
STUDY OBJECTIVES: To calculate cost-effectiveness of scenarios concerning lung transplantation in The Netherlands. DESIGN: Microsimulation model predicting survival, quality of life, and costs with and without transplantation program, based on data of
Al, M.J. (Maiwenn), Bij, W. (Wim) van der, Boer, W.J. (Wim) de, Enckevort, P.J. (Petra) van, Geertsma, A. (Albert), Koopmanschap, M.A. (Marc), Tenvergert, E.M. (Elisabeth)   +6 more
core  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source