Results 41 to 50 of about 219,832 (311)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Heart-Lung Transplantation

Investigative Radiology, 1989
Since the successful clinical reintroduction of heart and lung transplantation in 1981, more than 350 of these procedures have been performed worldwide. Although survival following this operation is less than that reported for heart transplantation, the results are improving. It is clear that the increased technical difficulty of the procedure combined
R S, Bonser, L S, Fragomeni, S W, Jamieson   +2 more
openaire   +4 more sources

The outcome of lung transplantation for end-stage pulmonary diseases with pulmonary hypertension: a single-center experience [PDF]

, 2022
Shilong Wu, Guilin Peng, Chenyang Xu, Xiuhua Li, Wenfa Jiang, Qing Ai, Chao Yang, Don Xiao, Bing Wei, Weizhe Huang, Xin Xu, Jianxing He   +11 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Efficacy of bronchial artery embolization in hemoptysis: longitudinal studyon survival and recurrence

CVIR Endovascular
Background and objectives Managing hemoptysis can be challenging due to recurrences after different treatment methods. This study aimed to assess the efficacy and long-term outcomes of bronchial artery embolization (BAE) in controlling hemoptysis and ...
Mohammad Sadegh Keshmiri, Bahamin Astani, Fatemeh Sadat Hosseini-Baharanchi, Babak Sharif-Kashani, Mahdi Ahmadinia, Sheida Mohammadi, Sepideh Ranjbar, Leila Saliminejad, Shadi Shafaghi   +8 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Contribution of 3D visualization and printing in teaching lung segments anatomy

3D Printing in Medicine
Background The knowledge and understanding of the anatomy of lung segments is of great importance while segmentectomies are increasingly performed. To introduce new technologies and tools in anatomy teaching could help students to improve their skills ...
Gabrielle Drevet, Valentin Soldea, Sylvain Gouttard, Melia Virely, Jean-Michel Maury, François Tronc   +5 more
doaj   +1 more source

Coronavirus disease 2019 outcomes in heart transplant recipients: a single-center case series

Journal of Medical Case Reports, 2021
Background With the rapidly expanding pandemic of severe acute respiratory syndrome coronavirus-2, a chronic immunosuppressed state in solid organ transplant recipients is a concern. We reported coronavirus disease 2019 in heart transplant recipients and
Farah Naghashzadeh, Shadi Shafaghi, Babak Sharif-Kashani, Payam Tabarsi, Leila Saliminejad, Sima Noorali   +5 more
doaj   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source