Results 41 to 50 of about 2,645,770 (342)

Post‐RSV Bronchial Web Formation in a Lung Transplant Recipient: A Case Report

Respirology Case Reports
Bronchial webs (BW) are fibrinous membranes which obstruct the airway lumen. A 33‐year‐old female presented with acute lung allograft dysfunction following a recent respiratory syncytial virus (RSV) infection, having undergone bilateral lung transplant 2 
Nathan Harb, Alexander Mullin, Celeste Mar, Rebecca Pearson, Adrian Havryk, Marshall Plit   +5 more
doaj   +1 more source

Coronavirus disease 2019 outcomes in heart transplant recipients: a single-center case series

Journal of Medical Case Reports, 2021
Background With the rapidly expanding pandemic of severe acute respiratory syndrome coronavirus-2, a chronic immunosuppressed state in solid organ transplant recipients is a concern. We reported coronavirus disease 2019 in heart transplant recipients and
Farah Naghashzadeh, Shadi Shafaghi, Babak Sharif-Kashani, Payam Tabarsi, Leila Saliminejad, Sima Noorali   +5 more
doaj   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Lung transplantation for emphysema [PDF]

Annals of Translational Medicine, 2020
Lung transplantation (LT) is proved to be effective in patients with end-stage lung disease who are failing optimal therapy. Chronic obstructive pulmonary disease (emphysema) is the most common indication for adult lung transplantation. As most patients with emphysema (EMP) can survive long term, it could be difficult to decide which patient should be ...
openaire   +4 more sources

Frailty phenotypes and mortality after lung transplantation: A prospective cohort study

American Journal of Transplantation, 2018
Frailty is associated with increased mortality among lung transplant candidates. We sought to determine the association between frailty, as measured by the Short Physical Performance Battery (SPPB), and mortality after lung transplantation.
J. Singer, J. Diamond, Michael R. Anderson, P. Katz, K. Covinsky, M. Oyster, Tatiana Blue, A. Soong, L. Kalman, Pavan Shrestha, S. Arcasoy, J. Greenland, L. Shah, J. Kukreja, N. Blumenthal, I. Easthausen, J. Golden, Amika McBurnie, E. Cantu, J. Sonett, S. Hays, H. Robbins, K. Raza, M. Bacchetta, R. Shah, F. D'Ovidio, A. Venado, J. Christie, D. Lederer   +28 more
semanticscholar   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Totally endoscopic non-robotic excision of aortic valve fibroelastoma: a case report

Journal of Cardiothoracic Surgery, 2022
Background Papillary fibroelastomas (PFEs) are a rare subtype of benign primary cardiac tumours, which are most commonly found on the aortic valve. Although median sternotomy is still used frequently there has been different attempts to remove the aortic
Sadia Batool, Arnaud Patoir, Amelie de Meaux, Marco Vola   +3 more
doaj   +1 more source

Detection, classification, and management of rejection after lung transplantation.

Journal of Thoracic Disease, 2019
Rejection is a major complication following lung transplantation. Acute cellular rejection, lymphocytic bronchiolitis, and antibody-mediated rejection (AMR) are all risk factors for the subsequent development of chronic lung allograft dysfunction (CLAD).
A. Parulekar, C. Kao
semanticscholar   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Cardiac Imaging in Patients After Fontan Palliation: Which Test and When?

Frontiers in Pediatrics, 2022
The Fontan operation represents the final stage of a series of palliative surgical procedures for children born with complex congenital heart disease, where a “usual” biventricular physiology cannot be restored.
Paolo Ciliberti, Paolo Ciancarella, Pasqualina Bruno, Davide Curione, Veronica Bordonaro, Veronica Lisignoli, Mario Panebianco, Marcello Chinali, Aurelio Secinaro, Lorenzo Galletti, Paolo Guccione   +10 more
doaj   +1 more source