Results 1 to 10 of about 475,202 (310)

Systemic Lupus Erythematosus with and without Anti-dsDNA Antibodies: Analysis from a Large Monocentric Cohort [PDF]

Mediators of Inflammation, 2015
Objectives. The anti-dsDNA antibodies are a marker for Systemic Lupus Erythematosus (SLE) and 70–98% of patients test positive. We evaluated the demographic, clinical, laboratory, and therapeutical features of a monocentric SLE cohort according to the ...
Conti Fabrizio, Ceccarelli Fulvia, Perricone Carlo, Massaro Laura, Marocchi Elisa, Miranda Francesca, Spinelli Francesca Romana, Truglia Simona, Alessandri Cristiano, Valesini Guido   +9 more
doaj   +2 more sources

Lupus nephritis [PDF]

Nature Reviews Disease Primers, 2020
Hans-Joachim Anders, Ramesh Saxena, Ioannis Parodis   +2 more
exaly   +3 more sources

Living with systemic lupus erythematosus in 2020: a European patient survey

Lupus Science and Medicine, 2021
Objective The aim of this study was to analyse the 2020 burden of Systemic Lupus Erythematosus (SLE) in Europe, from the patients’ perspective.Methods In May 2020, Lupus Europe, the European umbrella patient association for SLE, designed and disseminated
Alain Cornet, Kirsi Myllys, Jeanette Andersen, Angela Edwards   +3 more
doaj   +1 more source

Membrane and Soluble CD137 in Systemic Lupus Erythematosus: Role as Biomarkers for Disease Activity

Journal of Immunology Research, 2023
Objective. The role of T cells in the pathogenesis of systemic lupus erythematosus (SLE) has recently gained attention. Costimulatory molecules are membrane proteins strictly associated with T-cell receptor (TCR), acting by activating or inhibiting T ...
Fulvia Ceccarelli, Francesco Natalucci, Alessandra Di Filippo, Giulio Olivieri, Chiara Napoletano, Aurelia Rughetti, Marianna Nuti, Ilaria Grazia Zizzari, Fabrizio Conti   +8 more
doaj   +1 more source

Hydroxychloroquine treatment in European patients with lupus erythematosus: dosing, retinopathy screening and adherence

Lupus Science and Medicine, 2021
Background Use of hydroxychloroquine (HCQ) is common in patients with lupus erythematosus. Long-term use (ie, ≥5 years) and high-dose HCQ (ie, >5 mg/kg/day) are both risk factors for developing HCQ retinopathy.
Ronald F van Vollenhoven, Alain Cornet, Jeanette Andersen, Zgjim Osmani, Thijs J Schrama, Wendy Zacouris-Verweij, Susan Frankel, Irene E M Bultink   +7 more
doaj   +1 more source

Patients with systemic lupus erythematosus and their experience with vaccination against COVID-19: a descriptive and explanatory study

Reumatismo, 2022
Not ...
F. Ceccarelli, V. Covelli, G. Olivieri, F. Natalucci, C. Alessandri, F. Conti   +5 more
doaj   +1 more source

Development of Systemic Autoimmune Diseases in Healthy Subjects Persistently Positive for Antiphospholipid Antibodies: Long-Term Follow-Up Study

Biomolecules, 2022
We longitudinally followed a single-center cohort of anti-phospholipid (aPL) positive healthy subjects to evaluate the evolution to systemic autoimmune diseases (sAD) and to describe clinical and serological associated features.
Fulvia Ceccarelli, Francesco Natalucci, Giulio Olivieri, Carmelo Pirone, Licia Picciariello, Valeria Orefice, Simona Truglia, Francesca Romana Spinelli, Cristiano Alessandri, Antonio Chistolini, Fabrizio Conti   +10 more
doaj   +1 more source

A Toll for lupus [PDF]

, 2005
Toll-like receptor (TLR)-9 recognizes CpG motifs in microbial DNA. TLR9 signalling stimulates innate antimicrobial immunity and modulates adaptive immune responses including autoimmunity against chromatin, e.g., in systemic lupus erythematosus (SLE ...
Anders HJ, H-J Anders, Stacey KJ
core   +1 more source

Lupus erythematodes

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2023
ZusammenfassungDer kutane Lupus erythematodes manifestiert sich mit oder ohne systemische Beteiligung mit einem breiten klinischen Spektrum. Die Pathogenese der Erkrankung ist durch einen Toleranzverlust gegenüber körpereigenen Antigenen und einer chronisch schubweisen Aktivierung des angeborenen und adaptiven Immunsystems geprägt.
Claudia, Günther, Jörg, Wenzel
openaire   +2 more sources

KITD816V+ systemic mastocytosis associated with KITD816V+ acute erythroid leukaemia: first case report with molecular evidence for same progenitor cell derivation [PDF]

, 2009
Toll-like receptor (TLR)-9 recognizes CpG motifs in microbial DNA. TLR9 signalling stimulates innate antimicrobial immunity and modulates adaptive immune responses including autoimmunity against chromatin, e.g., in systemic lupus erythematosus (SLE ...
H-P Horny, K K Reichard, K Sotlar, M K Foucar, S A McClintock-Treep   +4 more
core   +1 more source