Results 1 to 10 of about 591,975 (259)

New efforts to incorporate patient-reported outcomes into lupus clinical trials: report of the community meeting convened by the Lupus Accelerating Breakthroughs Consortium (Lupus ABC), 16–17 October 2024 [PDF]

Lupus Science and Medicine
The Lupus Research Alliance formed the Lupus Accelerating Breakthroughs Consortium (Lupus ABC) in 2023 as a public-private partnership with investigators, pharmaceutical companies, the Food and Drug Administration, National Institutes of Health, patient ...
, Meenakshi Jolly, Zahi Touma, Anca D Askanase, Patricia Katz, Cindy Coney, Wen-Hung Chen, Josephine Park, Hoang Nguyen, Elektra Papadopoulos, Nicole Cooper, Brian Ung, Narae Yun, Teodora P Staeva, Nandan Baruah, Anna Fisch, Lili Garrard, Veronica Vargas Lupo, Judith Mills, Carla Menezes, Jeanine Cox, Carrie Eberspecher, Shanelle Gabriel, Shane Lerner, Malinda Logan, Erika Reyna, Elizabeth Santa Cruz, Veronica Vargas Lupo, Elizabeth Santa Cruz   +28 more
doaj   +2 more sources

The immune cell landscape in kidneys of patients with lupus nephritis [PDF]

Nature Immunology, 2019
Lupus nephritis is a potentially fatal autoimmune disease for which the current treatment is ineffective and often toxic. To develop mechanistic hypotheses of disease, we analyzed kidney samples from patients with lupus nephritis and from healthy control
Deepak A Rao, Celine C Berthier, Anne Davidson   +2 more
exaly   +2 more sources

Lupus Disseminatus [PDF]

Proceedings of the Royal Society of Medicine, 1927
J. A. Drake
openalex   +3 more sources

Lupus nephritis [PDF]

Nature Reviews Disease Primers, 2020
Hans-Joachim Anders, Ramesh Saxena, Ioannis Parodis   +2 more
exaly   +3 more sources

Living with systemic lupus erythematosus in 2020: a European patient survey

Lupus Science and Medicine, 2021
Objective The aim of this study was to analyse the 2020 burden of Systemic Lupus Erythematosus (SLE) in Europe, from the patients’ perspective.Methods In May 2020, Lupus Europe, the European umbrella patient association for SLE, designed and disseminated
Alain Cornet, Kirsi Myllys, Jeanette Andersen, Angela Edwards   +3 more
doaj   +1 more source

Hydroxychloroquine treatment in European patients with lupus erythematosus: dosing, retinopathy screening and adherence

Lupus Science and Medicine, 2021
Background Use of hydroxychloroquine (HCQ) is common in patients with lupus erythematosus. Long-term use (ie, ≥5 years) and high-dose HCQ (ie, >5 mg/kg/day) are both risk factors for developing HCQ retinopathy.
Ronald F van Vollenhoven, Alain Cornet, Jeanette Andersen, Zgjim Osmani, Thijs J Schrama, Wendy Zacouris-Verweij, Susan Frankel, Irene E M Bultink   +7 more
doaj   +1 more source

Membrane and Soluble CD137 in Systemic Lupus Erythematosus: Role as Biomarkers for Disease Activity

Journal of Immunology Research, 2023
Objective. The role of T cells in the pathogenesis of systemic lupus erythematosus (SLE) has recently gained attention. Costimulatory molecules are membrane proteins strictly associated with T-cell receptor (TCR), acting by activating or inhibiting T ...
Fulvia Ceccarelli, Francesco Natalucci, Alessandra Di Filippo, Giulio Olivieri, Chiara Napoletano, Aurelia Rughetti, Marianna Nuti, Ilaria Grazia Zizzari, Fabrizio Conti   +8 more
doaj   +1 more source

Patients with systemic lupus erythematosus and their experience with vaccination against COVID-19: a descriptive and explanatory study

Reumatismo, 2022
Not ...
F. Ceccarelli, V. Covelli, G. Olivieri, F. Natalucci, C. Alessandri, F. Conti   +5 more
doaj   +1 more source

Development of Systemic Autoimmune Diseases in Healthy Subjects Persistently Positive for Antiphospholipid Antibodies: Long-Term Follow-Up Study

Biomolecules, 2022
We longitudinally followed a single-center cohort of anti-phospholipid (aPL) positive healthy subjects to evaluate the evolution to systemic autoimmune diseases (sAD) and to describe clinical and serological associated features.
Fulvia Ceccarelli, Francesco Natalucci, Giulio Olivieri, Carmelo Pirone, Licia Picciariello, Valeria Orefice, Simona Truglia, Francesca Romana Spinelli, Cristiano Alessandri, Antonio Chistolini, Fabrizio Conti   +10 more
doaj   +1 more source

A Toll for lupus [PDF]

, 2005
Toll-like receptor (TLR)-9 recognizes CpG motifs in microbial DNA. TLR9 signalling stimulates innate antimicrobial immunity and modulates adaptive immune responses including autoimmunity against chromatin, e.g., in systemic lupus erythematosus (SLE ...
Anders HJ, H-J Anders, Stacey KJ
core   +1 more source