Results 31 to 40 of about 327,203 (311)

Lupus nephritis

Kidney International, 1997
Contains fulltext : 24337___.PDF (Publisher’s version ) (Open Access)
openaire   +3 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Gene-Expression-Guided Selection of Candidate Loci and Molecular Phenotype Analyses Enhance Genetic Discovery in Systemic Lupus Erythematosus

Clinical and Developmental Immunology, 2012
Systemic lupus erythematosus (SLE) is a highly heterogeneous autoimmune disorder characterized by differences in autoantibody profiles, serum cytokines, and clinical manifestations.
Yelena Koldobskaya, Kichul Ko, Akaash A. Kumar, Sandra Agik, Jasmine Arrington, Silvia N. Kariuki, Beverly S. Franek, Marissa Kumabe, Tammy O. Utset, Meenakshi Jolly, Andrew D. Skol, Timothy B. Niewold   +11 more
doaj   +1 more source

Research priorities in childhood-onset lupus: results of a multidisciplinary prioritization exercise

Pediatric Rheumatology Online Journal, 2019
Background Childhood-onset systemic erythematosus lupus (cSLE) is characterized by more severe disease, widespread organ involvement and higher mortality compared to adult-onset SLE. However, cSLE is largely underfunded to carry out necessary research to
Stacy P. Ardoin, R Paola Daly, Lyna Merzoug, Karin Tse, Kaveh Ardalan, Lisa Arkin, Andrea Knight, Tamar Rubinstein, Natasha Ruth, Scott E. Wenderfer, Aimee O. Hersh, on behalf of the Childhood Arthritis and Rheumatology Research Alliance and Lupus Foundation of America   +11 more
doaj   +1 more source

THE IDENTITY OF LUPUS VULGARIS AND LUPUS ERYTHEMATODES. [PDF]

JAMA: The Journal of the American Medical Association, 1896
In common with all other branches of medicine, dermatology has felt the result of modern bacteriologic investigations. The brilliant discoveries of Koch, the father of bacteriology, have shattered many idols and put a different aspect upon many things. The advances wrought have been so enormous as to thoroughly have revolutionized some matters.
openaire   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Review of presentations at the 6th European Lupus Meeting 3-5 March 2005. [PDF]

, 2005
The 6th European Lupus Meeting was held at the Royal College of Physicians of London and was attended by 450 delegates. The conference brought together leading speakers from Europe and North America who reviewed current knowledge and exciting new ...
Rahman, A, Ioannou, Y, Giles, IP, Bowman, SJ   +3 more
core  

Serum anti-lipocalin 2 IgG is a novel biomarker in the diagnosis of systemic lupus erythematosus

, 2014
Background: Previous work suggests that lipocalin 2 is involved in the pathogenesis of systemic lupus erythematosus (SLE) and that this novel antigen could serve as a high-quality renal biomarker of acute kidney injury in SLE.
Du, Y, Li, R., Li, Z. G., Ascherman, D P, Li, Y N, Feng, M, Hu, F L, Dai, Y J, Li, Z G, Jia, Y., Li, Y. N., Feng, M., Zhu, L, Zhu, L., Ma, X X, Du, Y., Ascherman, D. P., Jia, Y, Zhang, C. F., Ma, X. X., Dai, Y. J., Hu, F. L., Li, R, Zhang, C F   +23 more
core   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source