Results 11 to 20 of about 327,203 (311)

Lupus or not lupus? Neuropsychiatric symptom attribution in systemic lupus erythematosus [PDF]

Rheumatology, 2017
n ...
GOVONI, Marcello, BORTOLUZZI, Alessandra
openaire   +2 more sources

Early Discoid Lupus Erythematosus Protects Against Renal Disease In Patients With Systemic Lupus Erythematosus: Longitudinal Data From A Large Latin American Cohort [PDF]

, 2017
The objective of this study was to examine whether early discoid lupus erythematosus (DLE) would be a protective factor for further lupus nephritis in patients with systemic lupus erythematosus (SLE).
V.; Alvarellos, E. M.; Chacon-Diaz, M. J.; Sato, A.; Caeiro, L. T. L.; Neira, R.; Drenkard, C., E. I.; Soriano, G. J.; Aspey, D.; Saurit, F.; Haye Salinas, M. H.; Acevedo-Vasquez, O.; Iglesias-Gamarra, L. D.; Bao, G.; Cardiel, Pons-Estel, E. R.; Costallat, A.; Reyes-Llerena, G.; Pons-Estel, B. A.; Wojdyla   +19 more
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Autoantibodies against complement C1q in systemic lupus erythemathosus [PDF]

, 2008
Complement and C1q, the first component of the classical pathway of activation of the complement system, are considered to be involved in the pathogenesis of systemic lupus erythematosus (SLE), a systemic autoimmune disease.
Bigler, Cornelia
core   +1 more source

A Toll for lupus [PDF]

, 2005
Toll-like receptor (TLR)-9 recognizes CpG motifs in microbial DNA. TLR9 signalling stimulates innate antimicrobial immunity and modulates adaptive immune responses including autoimmunity against chromatin, e.g., in systemic lupus erythematosus (SLE ...
Anders, Hans-Joachim, H-J Anders
core   +1 more source

Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosus. [PDF]

, 2011
The long pentraxin PTX3 has multiple roles in innate immunity. For example, PTX3 regulates C1q binding to pathogens and dead cells and regulates their uptake by phagocytes. It also inhibits P-selectin-mediated recruitment of leukocytes.
Mantovani Alberto, Heni Eka Susanti, Adriana Migliorini, A. Migliorini, Susanti, Heni Eka, Hans-Joachim Anders, Christoph Römmele, Kulkarni, Onkar P., M. Lech, Cecilia Garlanda, Kulkarni Onkar P., Lech, Maciej, Lech Maciej, Garlanda Cecilia, C. Garlanda, Römmele, Christoph, Migliorini Adriana, Mantovani, Alberto, Alberto Mantovani, Anders Hans-Joachim, Onkar P Kulkarni, Maciej Lech, Susanti Heni Eka, A. Mantovani, Anders, Hans-Joachim, Römmele Christoph, H.E. Susanti, Migliorini, Adriana, O.P. Kulkarni, C. Römmele, H. J. Anders, Garlanda, Cecilia, Onkar P. Kulkarni   +32 more
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Lupus nephritis and lupus band test [PDF]

Postgraduate Medical Journal, 1981
Summary Twenty-seven patients with histologically confirmed lupus nephritis were studied to identify the incidence of lupus band and its significance to histological patterns of nephritis and complement levels. It was found that the kidney involvement is 2.5 times more frequent in lupus band positive patients.
B A, Adam, F, Wang, L M, Looi, K, Prathap   +3 more
openaire   +2 more sources

A randomised study of rituximab and belimumab sequential therapy in PR3 ANCA-associated vasculitis (COMBIVAS): design of the study protocol

Trials, 2023
Background Sequential B cell-targeted immunotherapy with BAFF antagonism (belimumab) and B cell depletion (rituximab) may enhance B cell targeting in ANCA-associated vasculitis (AAV) through several mechanisms.
Mark E. McClure, Seerapani Gopaluni, James Wason, Robert B. Henderson, Andre Van Maurik, Caroline C.O. Savage, Charles D. Pusey, Alan D. Salama, Paul A. Lyons, Jacinta Lee, Kim Mynard, David R. Jayne, Rachel B. Jones, on behalf the COMBIVAS investigators   +13 more
doaj   +1 more source

Kidney disease in lupus is not always 'lupus nephritis' [PDF]

Arthritis Research & Therapy, 2013
In lupus erythematosus, elevated serum creatinine levels and urinary abnormalities implicate a kidney disorder, which may not always be lupus nephritis as defined by the current classification of the International Society of Nephrology/Renal Pathology Society.
Anders, Hans-Joachim, Weening, Jan J.
openaire   +3 more sources

Neuropsychiatric Manifestations of Antiphospholipid Syndrome—A Narrative Review

Brain Sciences, 2022
Antiphospholipid syndrome (APS) is a common autoimmune pro-thrombotic condition characterised by thrombosis and pregnancy morbidity. There are a broad range of neuropsychiatric manifestations associated with APS, from focal symptoms to more global ...
Yik Long Man, Giovanni Sanna
doaj   +1 more source

Immunoglobulin abnormalities are frequent in patients with lupus nephritis

BMC Rheumatology, 2019
Background Hypogammaglobulinemia is a complication of B-cell targeting therapies (BCTT), used in vasculitis, rheumatoid arthritis and systemic lupus erythematosus (SLE).
M. J. Cuadrado, I. Calatayud, M. Urquizu-Padilla, S. Wijetilleka, S. Kiani-Alikhan, M. Y. Karim   +5 more
doaj   +1 more source