Results 31 to 40 of about 22,001 (226)

Lupus anticoagulant hypoprothrombinemia syndrome associated with bilateral adrenal haemorrhage in a child: early diagnosis and intervention

Thrombosis Journal, 2021
Background Lupus anticoagulant-hypoprothrombinemia syndrome (LAHPS) is characterized by bleeding and thrombosis in patients with autoimmune diseases or infections.
Atsushi Sakamoto, Masao Ogura, Atsushi Hattori, Kinji Tada, Reiko Horikawa, Hisaya Nakadate, Kimikazu Matsumoto, Keiji Nogami, Masahiro Ieko, Akira Ishiguro   +9 more
doaj   +1 more source

Clinical significance of antibodies to the phosphatidylserine/prothrombin complex

Современная ревматология, 2022
Classical serological markers of antiphospholipid syndrome (APS) are antibodies to cardiolipin, antibodies to β2-glycoprotein 1, and lupus anticoagulant.
T. M. Reshetnyak, F. A. Cheldieva, M. V. Cherkasova, A. M. Lila   +3 more
doaj   +1 more source

Lupus Anticoagulant, Von Willerbrand Factor and Interleukin-6 as a reliable predictor of the need for mechanical ventilation in Covid-19

Galicia Clínica
Background: Coronavirus disease 2019 is characterized by causing thromboembolic events due to a procoagulant state. The possible relationship between lupus anticoagulant and patient's procoagulant state is controversial and no study has specifically ...
Ana Latorre Díez, Mª Lourdes del Río-Solá, Raquel Gutiérrez López, Manuel Lorenzo López Reboiro, Raquel Fernández González, Paula Pesqueira Fontán, M.ª Teresa Alves Pérez, José López Castro   +7 more
doaj   +1 more source

Síndrome antifosfolípide Antiphospholipid syndrome

Anais Brasileiros de Dermatologia, 2005
Condição adquirida, sistêmica, caracterizada por tromboses recorrentes no sistema arterial, venoso ou ambos, a síndrome antifosfolípide pode ser primária ou secundária, esta última mais associada ao lúpus eritematoso sistêmico e menos freqüentemente a ...
Jesus Rodriguez Santamaria, Daniela Badziak, Michelle Ferreira de Barros, Fernando Luiz Mandelli, Leila Cristina Cavalin, Maurício Shigueru Sato   +5 more
doaj   +1 more source

Spermatic vein thrombosis with lupus anticoagulant, a cause of acute inguinal pain: a case report

The Pan African Medical Journal, 2020
Patients with lupus anticoagulants are at high risk of systemic arterial and venous thrombosis and arterial stroke. We present an unusual case of a young man presenting inguinal pain. Doppler ultrasound revealed spermatic vein thrombosis on the left side.
Mohammed Aynaou, Tarik Mhanna, Amine Elhoumaidi, Paapa Dua Boateng, Ali Barki   +4 more
doaj   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Nasal Skin Necrosis: A Very Rare Manifestation of Antiphospholipid Syndrome

European Journal of Case Reports in Internal Medicine, 2017
A 23-year-old woman, a smoker and oral oestrogen user, presented with nasal necrosis. No other symptoms or local trauma were described. Relevant laboratory findings included complement consumption, positive lupus-anticoagulant assay, increased rheumatoid
Carolina Oliveira Ourique, Inês Chora, Susana Guimarães, Sara Júlio, Paula Vaz-Marques   +4 more
doaj   +1 more source

Autoimmune hemolytic anemia as an initial presentation in children with systemic lupus erythematosus: two case reports

Journal of International Medical Research, 2022
We report the cases of two children who presented with autoimmune hemolytic anemia (AIHA) as an initial presentation of systemic lupus erythematosus (SLE).
Yan Lu, Xian-Mei Huang
doaj   +1 more source

Analytical dilemmas in lupus anticoagulant detection

Exploration of Immunology, 2023
Accurate lupus anticoagulant (LA) detection is crucial to antiphospholipid syndrome (APS) diagnosis. Detection is based on LA functional behavior in coagulation assays irrespective of epitope specificity. LA screening tests employ dilute phospholipids to
Gary W. Moore
doaj   +1 more source

Relative Exchangeable Copper Confirms Wilson Disease and Supports Reclassification of the ATP7B p.Met665Ile Variant With Conflicting Pathogenicity Evidence

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Wilson disease (WD) is an autosomal recessive disorder of copper metabolism caused by ATP7B mutations. Diagnosis is usually straightforward in symptomatic patients, but can be challenging in children and adolescents with mild liver disease, borderline urinary copper excretion, or inconclusive genetic findings.
Emanuele Nicastro, Caterina Zuccoli, Roberto Marozzi, Antonino Barletta, Lisa Licini, Paola Tebaldi, Valeria Casotti, Mariangela Stinco, Lidia Pezzani, Maria Iascone, Lorenzo D'Antiga   +10 more
wiley   +1 more source