Results 1 to 10 of about 9,990 (166)

Acquired hemophilia A in the setting of dual anticoagulation therapy and lupus anticoagulant: a case report

Journal of Medical Case Reports, 2022
Background Acquired hemophilia A is a disorder caused by autoantibodies against coagulation factor VIII that may present with severe bleeding. We report a rare case of acquired hemophilia A presenting with coexisting lupus anticoagulant.
Victor Chen, Lauren C. Roby, Stephanie Wentzel, Mingjia Li, Nicholas Jones   +4 more
doaj   +1 more source

Lupus anticoagulant: a clinical and laboratory diagnostic dilemma

Journal of Pathology of Nepal, 2022
Lupus anticoagulants are a group of diverse autoantibodies that interfere in vitro in phospholipid-dependent clotting tests, and inhibit both the common and intrinsic pathways of coagulation. Paradoxically, they are implicated to cause hypercoagulability,
Shalini Trivedi, Pooja Jain, Nutan Dixit, Manoj Arun, Udita Singhal   +4 more
doaj   +1 more source

A rare case of schizophrenia coexistence with antiphospholipid syndrome, β-thalassemia, and monoclonal gammopathy of undetermined significance

Frontiers in Psychiatry, 2023
A patient with schizophrenia who was treated with chlorpromazine developed lupus anticoagulant (LA) and antiphospholipid syndrome (APS). On protein electrophoresis, a monoclonal immunoglobulin A peak was seen in this patient, defining a condition of ...
Yingming Jin, Yiquan Cheng, Jifeng Mi, Jianfen Xu   +3 more
doaj   +1 more source

Prothrombin Is Responsible for the Lupus Cofactor Phenomenon in a Patient with Lupus Anticoagulant/Hypoprothrombinemia Syndrome

TH Open, 2020
Lupus anticoagulant is a misnomer as it is commonly associated with thromboembolic events. In few cases, the name retains its literal meaning when it characterizes patients with a bleeding disorder.
Vittorio Pengo, Lorena Zardo, Maria Grazia Cattini, Elisa Bison, Elena Pontara, Sara Altinier, Chunyan Cheng, Gentian Denas   +7 more
doaj   +1 more source

Autoimmune Factor V Deficiency That Took 16 Years to Diagnose due to Pseudodeficiency of Multiple Coagulation Factors

Case Reports in Medicine, 2021
A 70-year-old man presented to our hospital with intramuscular hemorrhage in the right thigh. He had exhibited a tendency to bleed for the last 16 years and had visited several medical institutions, but no diagnosis had been made.
Takaaki Kato, Takaya Hanawa, Mea Asou, Tomohiko Asakawa, Hisashi Sakamaki, Makoto Araki   +5 more
doaj   +1 more source

A Matter of Caution: Coagulation Parameters in COVID-19 Do Not Differ from Patients with Ruled-Out SARS-CoV-2 Infection in the Emergency Department

TH Open, 2021
COVID-19 (coronavirus disease 2019) patients often show excessive activation of coagulation, associated with increased risk of thrombosis. However, the diagnostic value of coagulation at initial clinical evaluation is not clear.
Wolfgang Bauer, Noa Galtung, Nick Neuwinger, Lutz Kaufner, Elisabeth Langer, Rajan Somasundaram, Rudolf Tauber, Kai Kappert   +7 more
doaj   +1 more source

Echocardiographic Abnormalities and Antiphospholipid Antibodies in Patients with Systemic Lupus Erythematosus

Arquivos Brasileiros de Cardiologia, 2002
OBJECTIVE: Lupus anticoagulant and anticardiolipin antibodies (aCL) have been associated with thrombosis, recurrent abortion, and thrombocytopenia in patients with systemic lupus erythematosus (SLE), but their relationship with cardiac disease is less ...
Creso Abreu Falcão, Izabel Cristina Alves, Wiliam Habib Chahade, Ângela Luzia Branco Pinto Duarte, Norma Lucena-Silva   +4 more
doaj   +1 more source

The effect of unfractionated heparin, enoxaparin, and danaparoid on lupus anticoagulant testing: Can activated carbon eliminate false‐positive results?

Research and Practice in Thrombosis and Haemostasis, 2020
Background Heparins and heparinoids interfere with functional clotting assays used for lupus anticoagulant (LAC) detection. However, current guidelines for LAC testing do not provide clear guidance on this matter.
Pieter M.M. De Kesel, Katrien M.J. Devreese   +1 more
doaj   +1 more source

Sickle cell trait: a cause of abdominal pain and pulmonary embolism

Revista de la Facultad de Ciencias Médicas de Córdoba, 2020
Introduction: Sickle cell trait (SCT) is a rare and underdiagnosed disorder in the Argentinian population. In this condition, individuals carry the mutation of the HbS gene in one of the two beta-globin genes.
Emanuel José Saad, Ayelén Tarditi Barra, Gabriela Monzoni, Carolina Villegas, Aldo Hugo Tabares   +4 more
doaj   +1 more source

The role of hypercoagulability in the development of osteonecrosis of the femoral head

Orthopedic Reviews, 2012
Despite the large number of the outstanding researches, pathogenesis of osteonecrosis remains unknown. During the last decades the hypothesis that increased intravascular coagulation may be the pathogenetic mechanism which leads to osteonecrosis is ...
Marios G. Lykissas, Ioannis P. Kostas-Agnantis, Ioannis D. Gelalis, Georgios Vozonelos, Anastasios V. Korompilias   +4 more
doaj   +1 more source