Results 21 to 30 of about 9,990 (166)

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Extracellular vesicles from pristane-treated CD38-deficient mice express an anti-inflammatory neutrophil protein signature, which reflects the mild lupus severity elicited in these mice

Frontiers in Immunology, 2022
In CD38-deficient (Cd38-/-) mice intraperitoneal injection of pristane induces a lupus-like disease, which is milder than that induced in WT mice, showing significant differences in the inflammatory and autoimmune processes triggered by pristane ...
Paula Carrillo-Rodríguez, José-Ángel Robles-Guirado, Adrián Cruz-Palomares, Miguel Ángel Palacios-Pedrero, Elena González-Paredes, Alex Más-Ciurana, Carolina Franco-Herrera, Paloma A. Ruiz-de-Castroviejo-Teba, Antonio Lario, Victoria Longobardo, Laura Montosa-Hidalgo, María M. Pérez-Sánchez-Cañete, María-Mercedes Corzo-Corbera, Sandra Redondo-Sánchez, Ana-Belén Jodar, Francisco J. Blanco, Esther Zumaquero, Ramón Merino, Jaime Sancho, Mercedes Zubiaur   +19 more
doaj   +1 more source

Acquired inhibitors to coagulation factors in a male patient with systemic lupus erythematosus: A case report and review of the literature

International Journal of Hematology and Oncology, 2012
Akkiz koagülasyon faktör inhibitörleri nadirdir ancak koagulasyon faktörlerinin disfonksiyonu veya otoümmün baskılanma nedenli akkiz kanama diyatezi yaşamı tehdit edebilir. Bu hastalıkla ilişkisiz olarak daha sık yaşlı hastalarda ortaya çıkar. Akkiz koagulasyon inhibitörleri aynı zamanda Sistemik Lupus Eritematozus (SLE) ile ilişkili olarak da meydana ...
Erdem, Özgür, Ayyıldız, Orhan, Aybak, Mehmet   +2 more
  +6 more sources

Mathematical modeling of cross-mixing test dynamics in adult-onset lupus Anticoagulant–Associated hypoprothrombinemia syndrome

Thrombosis Update
Lupus anticoagulant–associated hypoprothrombinemia syndrome (LAHPS) is a rare acquired bleeding disorder, and interpretation of coagulation mixing tests can be challenging, particularly in the presence of direct oral anticoagulants (DOACs).We report an ...
Noriko Seno, Takafumi Ohama, Natsuko Morita, Akiyoshi Takami, Masahiro Ieko, Kazuhiro Ikegame   +5 more
doaj   +1 more source

Comparative analysis of chromogenic vs clot based cdc modified, nijmegen-bethesda assay for detection of factor VIII inhibitor titre

Nigerian Journal of Medicine, 2019
Background:- Inhibitors to infused factor VIII are the most significant complication of hemophilia treatment. These inhibitors are usually IgG antibodies, that react with FVIII in a time and temperature dependent manner.
Mirza Asif Baig, Mohammad Shahid Iqbal, Abdel Rahim Mahmoud Muddathir, Aisha Tabassum, M Syeda Sarah   +4 more
doaj   +1 more source

Pitfalls in hemostasis exploration, a case report of a girl with Henoch-Schönlein type vasculitis

Romanian Journal of Laboratory Medicine, 2017
The adequate performance and correct interpretation of assays for coagulation factor inhibitors play a critical role for the hemostasis laboratory. Both, false positive and false negative inhibitor assays may be reported, leading to erroneous patient’s ...
Arghirescu Smaranda, Boia Eugen, Ursu Emilia, Savescu Delia, Boc Madalina, Jinca Cristian, Serban Margit   +6 more
doaj   +1 more source

An investigation to find the correlation between lupus anticoagulant and coagulation abnormalities in COVID-19 patients; a narrative review [PDF]

Journal of Nephropathology
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of coronavirus disease 2019 (COVID-19) which is associated with nonspecific respiratory syndromes, varying from mild symptoms of upper airway to required mechanical ventilation ...
Amir Aria, Ahmadreza Maghsoudi, Fatemeh Shafiee, Mahnaz Momenzadeh   +3 more
doaj   +1 more source

Kallikrein–Kinin System Suppresses Type I Interferon Responses: A Novel Pathway of Interferon Regulation

Frontiers in Immunology, 2018
The Kallikrein–Kinin System (KKS), comprised of kallikreins (klks), bradykinins (BKs) angiotensin-converting enzyme (ACE), and many other molecules, regulates a number of physiological processes, including inflammation, coagulation, angiogenesis, and ...
Alecia Seliga, Michael Hweemoon Lee, Nicole C. Fernandes, Viviana Zuluaga-Ramirez, Marta Didukh, Yuri Persidsky, Raghava Potula, Stefania Gallucci, Uma Sriram   +8 more
doaj   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

Prediction of recurrent venous thromboembolism by clot lysis time: a prospective cohort study. [PDF]

PLoS ONE, 2012
Venous thromboembolism (VTE) is a chronic disease, which tends to recur. Whether an abnormal fibrinolytic system is associated with an increased risk of VTE is unclear.
Ludwig Traby, Marietta Kollars, Lisbeth Eischer, Sabine Eichinger, Paul A Kyrle   +4 more
doaj   +1 more source