Results 21 to 30 of about 9,998 (163)

[Lupus anticoagulant-hypoprothrombinemia syndrome with a false-positive test for coagulation factor inhibitors].

[Rinsho ketsueki] The Japanese journal of clinical hematology, 2012
We report a case of a 1-year-old boy diagnosed with lupus anticoagulant-hypoprothrombinemia syndrome (LA-HPS), which is a rare disorder. His initial presentation of sinusitis was accompanied by hemorrhagic episodes including ecchymoses and epistaxis 6 months after antibiotic therapy.
MORINAGA, Shingo, IDE, Yoko, KUSUMOTO, Masaru, OGATA, Mika, TAKAKI, Kazutaka, MATSUMOTO, Emiko   +5 more
openaire   +2 more sources

Lupus anticoagulant-hypoprothrombinemia syndrome with lupus nephritis in a girl misdiagnosed with immunoglobulin A nephropathy: a case report [PDF]

Childhood Kidney Diseases
Distinguishing lupus nephritis (LN) from other glomerulopathies, such as immunoglobulin A nephropathy (IgAN), poses a diagnostic challenge owing to overlapping clinical and histopathologic findings. Lupus anticoagulant-hypoprothrombinemia syndrome (LAHPS)
Chung Ho Lee, Yo Han Ahn, Hee Gyung Kang, Ji Hyun Kim   +3 more
doaj   +1 more source

Extracellular vesicles from pristane-treated CD38-deficient mice express an anti-inflammatory neutrophil protein signature, which reflects the mild lupus severity elicited in these mice

Frontiers in Immunology, 2022
In CD38-deficient (Cd38-/-) mice intraperitoneal injection of pristane induces a lupus-like disease, which is milder than that induced in WT mice, showing significant differences in the inflammatory and autoimmune processes triggered by pristane ...
Paula Carrillo-Rodríguez, José-Ángel Robles-Guirado, Adrián Cruz-Palomares, Miguel Ángel Palacios-Pedrero, Elena González-Paredes, Alex Más-Ciurana, Carolina Franco-Herrera, Paloma A. Ruiz-de-Castroviejo-Teba, Antonio Lario, Victoria Longobardo, Laura Montosa-Hidalgo, María M. Pérez-Sánchez-Cañete, María-Mercedes Corzo-Corbera, Sandra Redondo-Sánchez, Ana-Belén Jodar, Francisco J. Blanco, Esther Zumaquero, Ramón Merino, Jaime Sancho, Mercedes Zubiaur   +19 more
doaj   +1 more source

Acquired inhibitors to coagulation factors in a male patient with systemic lupus erythematosus: A case report and review of the literature

International Journal of Hematology and Oncology, 2012
Akkiz koagülasyon faktör inhibitörleri nadirdir ancak koagulasyon faktörlerinin disfonksiyonu veya otoümmün baskılanma nedenli akkiz kanama diyatezi yaşamı tehdit edebilir. Bu hastalıkla ilişkisiz olarak daha sık yaşlı hastalarda ortaya çıkar. Akkiz koagulasyon inhibitörleri aynı zamanda Sistemik Lupus Eritematozus (SLE) ile ilişkili olarak da meydana ...
Erdem, Özgür, Ayyıldız, Orhan, Aybak, Mehmet   +2 more
  +6 more sources

Mathematical modeling of cross-mixing test dynamics in adult-onset lupus Anticoagulant–Associated hypoprothrombinemia syndrome

Thrombosis Update
Lupus anticoagulant–associated hypoprothrombinemia syndrome (LAHPS) is a rare acquired bleeding disorder, and interpretation of coagulation mixing tests can be challenging, particularly in the presence of direct oral anticoagulants (DOACs).We report an ...
Noriko Seno, Takafumi Ohama, Natsuko Morita, Akiyoshi Takami, Masahiro Ieko, Kazuhiro Ikegame   +5 more
doaj   +1 more source

Comparative analysis of chromogenic vs clot based cdc modified, nijmegen-bethesda assay for detection of factor VIII inhibitor titre

Nigerian Journal of Medicine, 2019
Background:- Inhibitors to infused factor VIII are the most significant complication of hemophilia treatment. These inhibitors are usually IgG antibodies, that react with FVIII in a time and temperature dependent manner.
Mirza Asif Baig, Mohammad Shahid Iqbal, Abdel Rahim Mahmoud Muddathir, Aisha Tabassum, M Syeda Sarah   +4 more
doaj   +1 more source

Pitfalls in hemostasis exploration, a case report of a girl with Henoch-Schönlein type vasculitis

Romanian Journal of Laboratory Medicine, 2017
The adequate performance and correct interpretation of assays for coagulation factor inhibitors play a critical role for the hemostasis laboratory. Both, false positive and false negative inhibitor assays may be reported, leading to erroneous patient’s ...
Arghirescu Smaranda, Boia Eugen, Ursu Emilia, Savescu Delia, Boc Madalina, Jinca Cristian, Serban Margit   +6 more
doaj   +1 more source

An investigation to find the correlation between lupus anticoagulant and coagulation abnormalities in COVID-19 patients; a narrative review [PDF]

Journal of Nephropathology
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of coronavirus disease 2019 (COVID-19) which is associated with nonspecific respiratory syndromes, varying from mild symptoms of upper airway to required mechanical ventilation ...
Amir Aria, Ahmadreza Maghsoudi, Fatemeh Shafiee, Mahnaz Momenzadeh   +3 more
doaj   +1 more source

Kallikrein–Kinin System Suppresses Type I Interferon Responses: A Novel Pathway of Interferon Regulation

Frontiers in Immunology, 2018
The Kallikrein–Kinin System (KKS), comprised of kallikreins (klks), bradykinins (BKs) angiotensin-converting enzyme (ACE), and many other molecules, regulates a number of physiological processes, including inflammation, coagulation, angiogenesis, and ...
Alecia Seliga, Michael Hweemoon Lee, Nicole C. Fernandes, Viviana Zuluaga-Ramirez, Marta Didukh, Yuri Persidsky, Raghava Potula, Stefania Gallucci, Uma Sriram   +8 more
doaj   +1 more source

Material‐Encoded Synchronization of Immunogenic Cell Death With Adenosine A2A Receptor Blockade Reprograms the Tumor Microenvironment

Advanced Science, EarlyView.
A bismuth–copper diselenide–based nanoplatform (BSCS@PHY) coordinates immunogenic cell death with local A2A receptor blockade in 4T1 tumors. Thermally triggered shell melting exposes catalytic surfaces for glutathione depletion and chemodynamic ROS generation, while co‐delivering an A2AR antagonist and yeast‐wall adjuvant to enhance dendritic‐cell ...
Xiangting Yi, Hanlou Yang, Junting Huang, Pengfei Wu, Shiying Zhou, Zunde Liao, Min Han, Zishan Chen, Xiaoyu Huang, Nan Ma, Jie Zhou, Mingqiang Li, Yiling Zhong   +12 more
wiley   +1 more source