Results 61 to 70 of about 20,230 (187)

The impact of systemic long‐term medications for the development of age‐related macular degeneration

Acta Ophthalmologica, Volume 104, Issue 6, Page 674-681, September 2026.
Abstract Purpose Age‐related macular degeneration (AMD) is a leading cause of central vision loss in the elderly; however, the systemic factors that modulate its incidence and progression remain unclear. We sought to determine whether long‐term use of systemic medications, including diabetes and antithrombotic medications, corticosteroids and ...
Hanna Heloterä, Reijo Sund, Toni Rikkonen, Kai Kaarniranta   +3 more
wiley   +1 more source

Impact of empiric potassium supplementation on mortality, sudden cardiac arrest and stroke in furosemide initiators

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2924-2936, August 2026.
Aim A prior non‐randomized study suggests that potassium supplementation may improve survival among furosemide initiators, and a randomized trial suggests that salt substitutes containing potassium might lower stroke risk. We conducted a retrospective cohort study using health‐care data to confirm or refute these associations among new users of ...
Thanh Phuong Pham Nguyen, Sean Hennessy, Colleen M. Brensinger, Warren B. Bilker, Laura M. Dember, Todd A. Miano, Tat‐Thang Vo, Allison W. Willis, Charles E. Leonard   +8 more
wiley   +1 more source

Development and Validation of an Interpretable Machine Learning‐Based Clinical Prediction Model for Short‐Term Mortality in Intracerebral Hemorrhage With Thrombocytopenia: A Multicenter Study

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
In this study, we developed and validated a clinical prediction model for the early prediction of short‐term mortality in patients with intracerebral hemorrhage complicated by thrombocytopenia. The model demonstrated good internal discrimination and acceptable external performance and may serve as a complementary tool for individualized risk ...
Dachang Qiu, Guangwei Li, Ze Wang, Lin Wang, Lanlan Wang, Yongfei Dong   +5 more
wiley   +1 more source

Thromboinflammatory biomarkers in obstetric pathophysiology: Predictive insights into placental insufficiency and feto‐maternal adverse outcomes

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Placental insufficiency is a thromboinflammatory disorder driven by angiogenic imbalance, complement activation, endothelial dysfunction and coagulation dysregulation, leading to microvascular thrombosis, impaired uteroplacental perfusion and adverse maternal and fetal outcomes, including pre‐eclampsia, fetal growth restriction and stillbirth. Abstract
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Current Controversies in Lupus Anticoagulant Detection

Antibodies, 2016
Antiphospholipid syndrome is an autoimmune, acquired thrombophilia diagnosed when vascular thrombosis or pregnancy morbidity are accompanied by persistent antiphospholipid antibodies.
Gary W. Moore
doaj   +1 more source

A case of propylthiouracil induced antineutrophil cytoplasmic antibody associated vasculopathy

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Nikhil Dwivedi, Jessica Witherspoon, Sarath Bodapati   +2 more
wiley   +1 more source

Using Preoperative Therapeutic Plasma Exchange in Lupus Anticoagulant Hypoprothrombinemia Syndrome to Achieve Hemostatic Factor II Activity: A Case Report

Journal of Clinical Apheresis, Volume 41, Issue 4, August 2026.
ABSTRACT Lupus anticoagulant hypoprothrombinemia syndrome (LA‐HPS) is a rare cause of acquired factor II deficiency associated with lupus anticoagulant due to antiprothrombin antibody, which predisposes to bleeding rather than thrombosis. We report a case of a 48‐year‐old female with LA‐HPS resulting in a bleeding diathesis due to acquired prothrombin ...
Puja Panwar, Sean G. Yates, Rebecca Yarborough, Yu‐Min Shen   +3 more
wiley   +1 more source

ANTIPHOSPHOLIPID SYNDROME IN OBJECTIVE PRACTICE

Мать и дитя в Кузбассе, 2018
The aim of the study – to study the spectrum of antiphospholipid antibodies in patients with fetal loss syndrome living in the Omsk region. Materials and methods. 80 patients with a history of fetal loss were examined. Results.
Анастасия Александровна Гончарова, Елена Николаевна Кравченко, Галина Владимировна Кривчик, Ирина Рахимжановна Вотрина, Вилена Юрьевна Чебакова   +4 more
doaj  

Preliminary Evaluation of a Novel Lupus Anticoagulant Activity Assay Unaffected by Anticoagulants

Journal of Clinical Laboratory Analysis, Volume 40, Issue 15, August 2026.
A novel one‐step lupus anticoagulant (LA) assay based on the LA‐sensitivity ratio (LA‐SR) was developed to simplify diagnostic testing and reduce potential interference from anticoagulants. The LA‐SR method showed good agreement with guideline‐based LA testing (dRVVT and/or LA‐sensitive APTT) for the detection of LA and demonstrated limited influence ...
Ayu Hidaka, Risa Kaneshige, Seika Nakamura, Yukari Motoki, Junzo Nojima   +4 more
wiley   +1 more source

Primary antiphospholipid syndrome in a hemodialysis patient with recurrent thrombosis of arteriovenous fistulas

Brazilian Journal of Nephrology
Introduction: The antiphospholipid syndrome is a systemic autoimmune disease defined by recurrent vascular and/or obstetrical morbidity that occurs in patients with persistent antiphospholipid antibodies.
Nikola Gjorgjievski, Pavlina Dzekova-Vidimliski   +1 more
doaj   +1 more source