Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury. [PDF]
, 2009 PurposeDeposition of fibrin in the alveolar space is a hallmark of acute lung injury (ALI). Plasminogen activator inhibitor-1 (PAI-1) is an antifibrinolytic agent that is activated during inflammation. Increased plasma and pulmonary edema fluid levels of
Brady, Sandra +4 more
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The role of hypercoagulability in the development of osteonecrosis of the femoral head
Orthopedic Reviews, 2012 Despite the large number of the outstanding researches, pathogenesis of osteonecrosis remains unknown. During the last decades the hypothesis that increased intravascular coagulation may be the pathogenetic mechanism which leads to osteonecrosis is ...
Marios G. Lykissas +4 more
doaj +1 more source
Research and Practice in Thrombosis and Haemostasis, 2021 Background The use of direct oral anticoagulants (DOACs) is a convenient therapeutic option for patients at risk of thrombosis. DOACs interfere with clot‐based testing for the identification of lupus anticoagulant antibodies (LACs) in patients with ...
Steven Andrew Baker +4 more
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Lupus anticoagulant hypoprothrombinemia syndrome associated with a hemorrhagic ovarian cyst in a girl with systemic lupus erythematosus : a case report [PDF]
Childhood Kidney DiseasesLupus anticoagulant hypoprothrombinemia syndrome (LAHPS) is a rare entity characterized by the presence of lupus anticoagulant (LA) and prothrombin (factor II) deficiency. It may cause severe bleeding contrary to classical antiphospholipid syndrome. Here,
Min Hwa Son, Hyung Eun Yim
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Frontiers in Neurology, 2020 Background: Lupus anticoagulant (LA) owns procoagulant properties in vivo and prolongs phospholipid-dependent clotting times in vitro. The prolonged in vitro clotting time can be misinterpreted as a bleeding disorder.
Aydin Huseynov +10 more
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Hematuria as the first sign of multiple myeloma
Clinical Case Reports, 2017 Key Clinical Message Patients with multiple myeloma may present with several signs and symptoms, inclusive of hemorrhagic diathesis. This case emphasizes the need to suspect uncommon etiologies for common signs and to be aware of the atypical effects of ...
Mariana Alves +4 more
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Agarose gel serum protein electrophoresis in cats with and without lymphoma and preliminary results of tandem mass fingerprinting analysis [PDF]
, 2011 <b>Background</b>: Serum electrophoretic profiles in cats are poorly characterized with respect to the protein components of the globulin fractions, and interpretation of the electrophoretograms has routinely been done in ignorance of the ...
Baker +36 more
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microRNA expression in peripheral blood cells following acute ischemic stroke and their predicted gene targets. [PDF]
, 2014 BackgroundmicroRNA (miRNA) are important regulators of gene expression. In patients with ischemic stroke we have previously shown that differences in immune cell gene expression are present.
Ander, Bradley P +5 more
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Lupus anticoagulant-hypoprothrombinemia syndrome with lupus nephritis in a girl misdiagnosed with immunoglobulin A nephropathy: a case report [PDF]
Childhood Kidney DiseasesDistinguishing lupus nephritis (LN) from other glomerulopathies, such as immunoglobulin A nephropathy (IgAN), poses a diagnostic challenge owing to overlapping clinical and histopathologic findings. Lupus anticoagulant-hypoprothrombinemia syndrome (LAHPS)
Chung Ho Lee +3 more
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Frontiers in Immunology, 2022 In CD38-deficient (Cd38-/-) mice intraperitoneal injection of pristane induces a lupus-like disease, which is milder than that induced in WT mice, showing significant differences in the inflammatory and autoimmune processes triggered by pristane ...
Paula Carrillo-Rodríguez +19 more
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