Results 241 to 250 of about 154,096 (287)
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New insights into the progression from cutaneous lupus to systemic lupus erythematosus

Expert Review of Clinical Immunology, 2020
Introduction Between 5 and 25% of patients with cutaneous lupus erythematosus (CLE) can progress to systemic lupus erythematosus (SLE) during the course of the disease. There is no clear predictive guideline for the progression of CLE to SLE.
Wenhui Zhou   +3 more
semanticscholar   +1 more source

Cutaneous lupus erythematosus

Seminars in Cutaneous Medicine and Surgery, 2001
Lupus erythematosus (LE) has many different clinical manifestations including a variety of cutaneous findings. Some of the cutaneous manifestations are not specific for LE, such as photosensitivity reactions, oral ulcers, alopecia, urticaria, vasculitis, vesiculo-bullous lesions, acral changes, cutaneous mucinoses, and cutaneous calcinosis.
openaire   +3 more sources

Thalidomide in Cutaneous Lupus Erythematosus

American Journal of Clinical Dermatology, 2003
For nearly 50 years, thalidomide has struggled between success and controversy. After causing an epidemic of phocomelia and other birth defects during the 1960s, affecting thousands of neonates, thalidomide was used as a sedative in selective disorders including leprosy.
Victoria P. Werth, Michelle T. Pelle
openaire   +2 more sources

Cutaneous lupus erythematosus

2016
Lupus erythematosus (LE) is an inflammatory autoimmune disease, characterized by a heterogeneous clinical presentation. The skin lesions are one of the most frequent symptoms of the disease and present with a broad spectrum of LE-nonspecific and LE-specific cutaneous manifestations. Therefore, the development of a classification for skin lesions in the
Aysche Landmann   +2 more
openaire   +2 more sources

Therapy of Cutaneous Lupus Erythematosus

Medical Clinics of North America, 1982
Cutaneous lupus erythematosus occurs in a spectrum from limited cutaneous disease to severe systemic disease. Chronic DLE generally follows a benign course, but rare transformation to systemic disease may occur. Subacute cutaneous LE is associated with a specific cutaneous lesion and mild to moderate systemic symptoms.
openaire   +4 more sources

Subacute cutaneous lupus erythematosus

Journal of the Royal Army Medical Corps, 2016
A 31-year-old female soldier developed subacute cutaneous lupus erythematosus, which remained undiagnosed for 4 years. Referral to dermatology and a punch biopsy confirmed the diagnosis and effective treatment was instituted. The presence of an unresolving annular rash in light-exposed areas, especially in a young woman, should prompt thorough ...
Jacqueline Furzeland, P Malcolm
openaire   +3 more sources

PD-1H (VISTA)–mediated suppression of autoimmunity in systemic and cutaneous lupus erythematosus

Science Translational Medicine, 2019
PD-1H (VISTA) is immunosuppressive during lupus progression and could be targeted by an agonistic antibody for therapy. Supporting a suppressor for lupus treatment Autoimmunity can result when the intricate checks and balances in the immune system are ...
Xue Han   +18 more
semanticscholar   +1 more source

Chronic Cutaneous Lupus Erythematosus

Medical Clinics of North America, 1989
Chronic cutaneous LE is a diverse disease, characterized by predominantly cutaneous disease with few systemic complications. Discoid lesions are commonly seen, but they are not specific for chronic cutaneous LE. These scarring and disfiguring changes are also present in neonatal LE, SLE, and complement deficiency LE. Because definitive diagnosis cannot
Robert E. Jordon, Sharon R. Hymes
openaire   +3 more sources

Histopathology of cutaneous lupus erythematosus

Clinics in Dermatology, 1985
The basic histopathologic feature of all cutaneous lesions of lupus erythematosus involves a perivascular mononuclear cell infiltrate with subsequent involvement of the epidermis and appendages. The various histologic alterations affecting the epidermis, dermis, and adnexal structures reflect the particular type of lesion biopsied and the duration of ...
Evan R. Farmer, Antoinette F. Hood
openaire   +3 more sources

Spectrum of cutaneous lupus erythematosus in South Africans with systemic lupus erythematosus

Lupus, 2019
Background Cutaneous involvement is very common in systemic lupus erythematosus. We describe the prevalence and spectrum of lupus-specific (cutaneous lupus erythematosus) and non-specific cutaneous features amongst mostly black South Africans with ...
K. Koch, M. Tikly
semanticscholar   +1 more source

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