Results 31 to 40 of about 29,202 (224)

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

Arthritis &Rheumatology, EarlyView.
Objective TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...
Ismail Yaz, Seza Ozen, Hacer Neslihan Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet Emin Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet Orhan Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan   +13 more
wiley   +1 more source

Cutaneous lupus erythematosus: pathogenesis, clinical pattern, diagnostics, therapy

Vestnik Dermatologii i Venerologii, 2017
This article contains the latest information about the mechanisms of development of lupus erythematosus based on the literature review. The modern classification of specific and non-specific skin lesions in lupus erythematosus is shown.The authors ...
P. N. Trofimov, O. V. Antonova, D. N. Shvyrev, V. R. Khairutdinov, I. E. Belousova, A. V. Samtsov   +5 more
doaj   +1 more source

Abatacept Reduces CD319+ (SLAMF7) Cytotoxic T Cells and Cytokine Production in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Systemic sclerosis (SSc) is characterized by immune dysregulation and fibrosis. We investigated whether abatacept modulates CD319/SLAMF7‐expressing cytotoxic T cells implicated in diffuse cutaneous SSc. Methods In this ancillary ASSET trial analysis, peripheral blood mononuclear cells from 67 participants were analyzed at baseline and months ...
Mikel Gurrea‐Rubio, Laura A. Cooney, Kohei Maeda, Phillip L. Campbell, Qi Wu, Camila I. Amarista, Alexander Stinson, Ray Ohara, Yang Mao‐Draayer, Michael L. Whitfield, Shiv Pillai, Poulami Dey, Johann E. Gudjonsson, Pei‐Suen Tsou, Dinesh Khanna, David A. Fox   +15 more
wiley   +1 more source

Lúpus comedônico: rara apresentação do lúpus eritematoso discoide Comedonic lupus: a rare presentation of discoid lupus erythematosus

Anais Brasileiros de Dermatologia, 2011
Lúpus eritematoso cutâneo crônico é doença autoimune, com apresentações polimorfas que podem, eventualmente, mimetizar outras condições clínicas, causando dificuldade diagnóstica.
Daniela Ferro Farias, Roberta Marinho Falcão Gondim, Isabella Portela Redighieri, Helena Muller, Valéria Petri   +4 more
doaj   +1 more source

Nonisomorphic and nonisotopic multidermatomal discoid lupus erythematosus – A rare subtype of cutaneous lupus erythematosus

Indian Dermatology Online Journal, 2020
Discoid lupus erythematosus (DLE) is the most common variant of chronic cutaneous lupus erythematosus. Several cases of Blaschko-linear lupus erythematosus, which is regarded as a distinct subtype of lupus erythematosus, have been reported across the ...
Sanjiv Choudhary, Ankita Srivastava, Mukesh Sahni, Santosh Tummudi   +3 more
doaj   +1 more source

Expert Perspectives: Toward Treat‐to‐Target Management in Adult Idiopathic Inflammatory Myopathies

Arthritis &Rheumatology, EarlyView.
Treat‐to‐target has transformed the management of several rheumatic diseases through predefined therapeutic goals, structured disease assessment, and timely treatment adjustment. Despite major advances in the understanding and treatment of idiopathic inflammatory myopathies (IIM), a formal treat‐to‐target framework for adult IIM has not yet been ...
Shiri Keret, Nantakarn Pongtarakulpanit, Rohit Aggarwal   +2 more
wiley   +1 more source

Chilblain lupus erythematosus in an adolescent girl

Indian Dermatology Online Journal, 2014
Chilblain Lupus Erythematosus (CHLE) is a rare form of cutaneous lupus erythematosus (LE), more frequently seen in middle aged females. It is characterized by erythematous to violaceous plaques over the acral areas induced by exposure to cold or drop in ...
Shikha Bansal, Alka Goel
doaj   +1 more source

Subacute cutaneous lupus erythematosus starting as linear lupus erythematosus [PDF]

International Journal of Dermatology, 2015
AbstractBackgroundCutaneous lupus in childhood is usually associated with systemic lupus erythematosus (LE). Linear cutaneous LE (LCLE) is an unusual presentation mostly seen in children and young adults.MethodsWe report a rare case of cutaneous subacute LE with a segmentary pattern following the lines of Blaschko in an 18‐month‐old girl with a 2‐month
Frances L, Betlloch I, Leiva-Salinas M, Marin I, Pascual J   +4 more
openaire   +3 more sources

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Atypical and rare forms of systemic lupus erythematosus, clinical manifestations and therapy. Part I. Skin lesions

Научно-практическая ревматология
Most patients with systemic lupus erythematosus (SLE) present with some form of skin involvement. Skin manifestations of lupus are classified as lupus-specific or lupus-nonspecific based on histopathologic findings.
S. K. Solovyev, E. A. Aseeva
doaj   +1 more source