Results 61 to 70 of about 136,973 (214)

Cutaneous lupus erythematosus in dogs: a comprehensive review

open access: yesBMC Veterinary Research, 2018
Since the first description of discoid lupus erythematosus (LE) in two dogs in 1979, the spectrum of canine cutaneous lupus erythematosus (CLE) variants has expanded markedly.In this review, we first propose an adaptation of the Gilliam-Sontheimer ...
T. Olivry, K. Linder, F. Banovic
semanticscholar   +1 more source

Classifying discoid lupus erythematosus: background, gaps, and difficulties

open access: yesInternational Journal of Women's Dermatology, 2017
To inform our ongoing efforts to develop defining features to be incorporated into a novel set of classification criteria for discoid lupus erythematosus (DLE), we conducted a literature review using the Ovid MEDLINE database.
Jessica S. Haber, BA   +2 more
doaj  

COMO: A Pipeline for Multi-Omics Data Integration in Metabolic Modeling and Drug Discovery [PDF]

open access: yesarXiv, 2020
Identifying potential drug targets using metabolic modeling requires integrating multiple modeling methods and heterogenous biological datasets, which can be challenging without sophisticated tools. We developed COMO, a user-friendly pipeline that integrates multi-omics data processing, context-specific metabolic model development, simulations, drug ...
arxiv  

Lúpus comedônico: rara apresentação do lúpus eritematoso discoide Comedonic lupus: a rare presentation of discoid lupus erythematosus

open access: yesAnais Brasileiros de Dermatologia, 2011
Lúpus eritematoso cutâneo crônico é doença autoimune, com apresentações polimorfas que podem, eventualmente, mimetizar outras condições clínicas, causando dificuldade diagnóstica.
Daniela Ferro Farias   +4 more
doaj   +1 more source

Optics-less smart sensors and a possible mechanism of cutaneous vision in nature [PDF]

open access: yes, 2008
Optics-less cutaneous (skin) vision is not rare among living organisms, though its mechanisms and capabilities have not been thoroughly investigated. This paper demonstrates, using methods from statistical parameter estimation theory and numerical simulations, that an array of bare sensors with a natural cosine-law angular sensitivity arranged on a ...
arxiv   +1 more source

Utility of CD123 immunohistochemistry in differentiating lupus erythematosus from cutaneous T cell lymphoma

open access: yesHistopathology, 2019
Histopathological overlap between lupus erythematosus and certain types of cutaneous T cell lymphoma (CTCL) is well documented. CD123+ plasmacytoid dendritic cells (PDCs) are typically increased in lupus erythematosus, but have not been well studied in ...
Stephanie J T Chen   +4 more
semanticscholar   +1 more source

A Case of Tumid Lupus Erythematosus Successfully Treated with Topical Tacrolimus and Hydrocortisone 17-Butyrate

open access: yesGazi Medical Journal
Tumid lupus erythematosus is an uncommon subtype of chronic cutaneous lupus erythematosus. Hereby, we report a 36-year-old male patient with tumid lupus erythematosus who presented with erythematous papules and plaques on the face and neck who showed ...
Funda Tamer   +3 more
doaj   +1 more source

Autologous Fat Transfer in a Patient with Lupus Erythematosus Profundus

open access: yesCase Reports in Dermatology, 2012
Lupus erythematosus profundus, a form of chronic cutaneous lupus erythematosus, is a rare inflammatory disease involving in the lower dermis and subcutaneous tissues. It primarily affects the head, proximal upper arms, trunk, thighs, and presents as firm
Jimi Yoon   +5 more
doaj   +1 more source

Integrated machine learning pipeline for aberrant biomarker enrichment (i-mAB): characterizing clusters of differentiation within a compendium of systemic lupus erythematosus patients [PDF]

open access: yesarXiv, 2018
Clusters of differentiation (CD) are cell surface biomarkers that denote key biological differences between cell types and disease state. CD-targeting therapeutic monoclonal antibodies (mAB) afford rich trans-disease repositioning opportunities. Within a compendium of systemic lupus erythematous (SLE) patients, we applied the Integrated machine ...
arxiv  

Assessment of Response to B-Cell Depletion Using Rituximab in Cutaneous Lupus Erythematosus

open access: yesJAMA dermatology, 2018
Importance Cutaneous lupus erythematosus (CLE) can be severe and treatment resistant. B-cell depletion therapy (BCDT) with rituximab is well recognized in organ involvement in systemic lupus erythematosus (SLE), but its efficacy in cutaneous ...
Rita Quelhas da Costa   +3 more
semanticscholar   +1 more source

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