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Systemic lupus erythematosus [PDF]
Nature Reviews Disease Primers, 2016 Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect many organs, including the skin, joints, the central nervous system and the kidneys. Women of childbearing age and certain racial groups are typically predisposed to developing the condition. Rare, inherited, single-gene complement deficiencies are strongly associated with SLE,
Kaul, Arvind +7 more
semanticscholar +10 more sources
The LancetSystemic lupus erythematosus (SLE) is a multisystemic autoimmune disease characterised by the presence of autoantibodies towards nuclear antigens, immune complex deposition, and chronic inflammation at classic target organs such as skin, joints, and kidneys.
Bowers W, Blum MA.
europepmc +3 more sources
Systemic lupus erythematosus [PDF]
BMJ, 2006 Systemic lupus erythematosus (SLE) is a multisystem autoimmune connective tissue disorder with various clinical presentations. It is prevalent among young women with a peak age of onset between the late teens and early 40s and a female to male ratio of 9:1. It is more common in certain ethnic groups, such as people with African or Asian ancestry.
Manson Jessica J, Rahman Anisur
+10 more sources
Systemic lupus erythematosus [PDF]
Drug and Therapeutics Bulletin, 1996 It has been estimated that about 3 in 10 000 people in Britain's cities have systemic lupus erythematosus (SLE)1 and the true figure may be higher.2 Forty years ago, approximately 50% of patients with SLE died within 4 years of diagnosis.3 Prospects have improved with refinements in therapy and the recognition of mild forms of the disease.
M S, Klein-Gitelman, M L, Miller
+7 more sources
EULAR recommendations for the management of systemic lupus erythematosus: 2023 update
Annals of the Rheumatic Diseases, 2023 Objectives To update the EULAR recommendations for the management of systemic lupus erythematosus (SLE) based on emerging new evidence. Methods An international Task Force formed the questions for the systematic literature reviews (January 2018–December ...
A. Fanouriakis +41 more
semanticscholar +1 more source
Brain Sciences, 2021 (1) Background: The Antiphospholipid Syndrome (APS) is a systemic autoimmune disorder characterized by arterial and/or venous thrombosis, pregnancy morbidity and raised titers of antiphospholipid antibodies.
Alba Jerez-Lienas +9 more
doaj +1 more source
Annals of the Rheumatic Diseases, 2022 Objectives To quantify global, regional and country-specific estimates of epidemiology of systemic lupus erythematosus (SLE). Methods Four databases were systematically searched, and a Bayesian hierarchical linear mixed model was constructed to estimate ...
Jingru Tian +4 more
semanticscholar +1 more source
Systemic Lupus Erythematosus [PDF]
New England Journal of Medicine, 2012 Systemic lupus erythematosus (SLE) is the prototypical autoimmune disease, associated with autoantibody production and evidence for immune complex deposition among the many aspects of its pathophysiology. SLE occurs most commonly in women during their reproductive years.
Micha, Rapoport, Olga, Bloch
+9 more sources
Arthritis & Rheumatology, 2019 To develop new classification criteria for systemic lupus erythematosus (SLE) jointly supported by the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR).
M. Aringer +63 more
semanticscholar +2 more sources
Science Progress, 2021 Background: Systemic lupus erythematosus is a common autoimmune disease involving multiple systems. Clinical involvement of the central and peripheral nervous systems is not unusual, but peripheral neuropathy in systemic lupus erythematosus with chronic ...
Liu Wang +6 more
doaj +1 more source