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Systemic lupus erythematosus [PDF]

open access: yesNature Reviews Disease Primers, 2016
Essential facts Systemic lupus erythematosus (SLE) is a rare, chronic autoimmune disease that causes inflammation in various parts of the body. Its annual incidence is estimated at one in 20,000. Although there is no cure, early diagnosis and appropriate treatment can help to control the symptoms, preventing damage to vital organs.
Zahi Touma   +2 more
exaly   +12 more sources

Reduced serum Sestrin-1 is associated with subclinical cardiovascular alterations in systemic lupus erythematosus: A controlled cross-sectional study [PDF]

open access: yesJournal of International Medical Research
Objective Systemic lupus erythematosus is associated with increased cardiovascular morbidity, even in the absence of overt clinical disease. Sestrin-1 is a stress-responsive antioxidant protein implicated in oxidative homeostasis and cardiovascular ...
Cahit Ucar   +5 more
doaj   +2 more sources

Pincer nails: an initial and isolated cutaneous manifestation of systemic lupus erythematosus

open access: yesPrzegląd Dermatologiczny, 2017
Introduction . Pincer nail deformity due to systemic lupus erythematosus is a rare phenomenon and only three cases have been reported to date. Objective . To present a case of pincer nails in a systemic lupus erythematosus patient and a brief review of
Manoj Karbhari Pawar
doaj   +2 more sources

Systemic Lupus Erythematosus [PDF]

open access: yesClinical and Developmental Immunology, 2012
Systemic lupus erythematosus (SLE) is the prototypical autoimmune disease, associated with autoantibody production and evidence for immune complex deposition among the many aspects of its pathophysiology. SLE occurs most commonly in women during their reproductive years.
Chaim Putterman   +3 more
  +9 more sources

Systemic lupus erythematosus [PDF]

open access: yesIndian Journal of Dental Research, 2006
Desquamative gingival lesions are non-plaque induced inflammatory gingival lesions. It is a clinical description and not a diagnosis. These desquamative lesions represent oral manifestations of various dermatoses. Systemic lupus erythematous (SLE), one of the rare dermatoses shows desquamative lesions as the oral manifestation.
Jayakumar N   +3 more
  +10 more sources

Cerebral Vein Thrombosis in the Antiphospholipid Syndrome: Analysis of a Series of 27 Patients and Review of the Literature

open access: yesBrain Sciences, 2021
(1) Background: The Antiphospholipid Syndrome (APS) is a systemic autoimmune disorder characterized by arterial and/or venous thrombosis, pregnancy morbidity and raised titers of antiphospholipid antibodies.
Alba Jerez-Lienas   +9 more
doaj   +1 more source

Progressive muscle weakness and amyotrophy during pregnancy as the first manifestation of systemic lupus erythematosus: A case report and review of literature

open access: yesScience Progress, 2021
Background: Systemic lupus erythematosus is a common autoimmune disease involving multiple systems. Clinical involvement of the central and peripheral nervous systems is not unusual, but peripheral neuropathy in systemic lupus erythematosus with chronic ...
Liu Wang   +6 more
doaj   +1 more source

Systemic lupus erythematosus [PDF]

open access: yesDrug and Therapeutics Bulletin, 1996
It has been estimated that about 3 in 10 000 people in Britain's cities have systemic lupus erythematosus (SLE)1 and the true figure may be higher.2 Forty years ago, approximately 50% of patients with SLE died within 4 years of diagnosis.3 Prospects have improved with refinements in therapy and the recognition of mild forms of the disease.
M S, Klein-Gitelman, M L, Miller
  +7 more sources

Systemic lupus erythematosus with trisomy X: a case report and review of the literature

open access: yesJournal of Medical Case Reports, 2022
Background The cause of systemic lupus erythematosus is not completely clear so far, but the prevalence of systemic lupus erythematosus is significantly increased in people with additional X chromosomes.
Fang Luo, Qiao Ye, Jie Shen
doaj   +1 more source

Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosus. [PDF]

open access: yes, 2011
The long pentraxin PTX3 has multiple roles in innate immunity. For example, PTX3 regulates C1q binding to pathogens and dead cells and regulates their uptake by phagocytes. It also inhibits P-selectin-mediated recruitment of leukocytes.
Mantovani Alberto   +32 more
core   +1 more source

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