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Systemic Lupus Erythematosus [PDF]
Clinical and Developmental Immunology, 2012 Systemic lupus erythematosus (SLE) is the prototypical autoimmune disease, associated with autoantibody production and evidence for immune complex deposition among the many aspects of its pathophysiology. SLE occurs most commonly in women during their reproductive years.
Anne Davidson +3 more
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Systemic lupus erythematosus [PDF]
Orphanet Journal of Rare Diseases, 2006 Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease, which is autoimmune in origin and is characterized by the presence of autoantibodies directed against nuclear antigens. It is a multi-system disease, and patients can present in vastly different ways.
Anisur Rahman, Jessica J Manson
+11 more sources
Systemic Lupus Erythematosus [PDF]
Cell, 1996 Systemic Lupus Erythematosus (SLE) of childhood is a complex and challenging disease which can occur at any age. Identification of disease early in it's course and aggressive, appropriate management leads to improved outcome for an individual child. The history of SLE indicates how much progress has been made in the last quarter century.
Marisa S. Klein-Gitelman +1 more
openaire +6 more sources
Comparison of structural magnetic resonance imaging findings between neuropsychiatric systemic lupus erythematosus and systemic lupus erythematosus patients: A systematic review and meta-analysis [PDF]
, 2017 Introduction: Neuropsychiatric systemic lupus erythematosus is often clinically challenging to diagnose, treat and monitor. Although brain magnetic resonance imaging is frequently performed before lumbar puncture in neuropsychiatric systemic lupus ...
Amin, O +4 more
core +1 more source
, 2011 Objective This study was conducted with sera from patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and arthritis and lupus-like disease animal models to identify innate immune system-dependent and -independent ...
Burmester, G. +5 more
core +2 more sources
Complement Activation in Patients With Probable Systemic Lupus Erythematosus and Ability to Predict Progression to American College of Rheumatology-Classified Systemic Lupus Erythematosus. [PDF]
, 2020 ObjectiveTo evaluate the frequency of cell-bound complement activation products (CB-CAPs) as a marker of complement activation in patients with suspected systemic lupus erythematosus (SLE) and the usefulness of this biomarker as a predictor of the ...
Alexander, Roberta Vezza +12 more
core +2 more sources
Cancer complicating systemic lupus erythematosus--a dichotomy emerging from a nested case-control study [PDF]
, 2013 We determined whether any individual cancers are increased or decreased in a cohort of 595 patients with systemic lupus erythematosus (SLE) followed for up to 32 years at the University College London Hospitals Lupus Clinic, looking for any associated ...
Dey, D, Isenberg, DA, Kenu, E
core +1 more source
Systemic lupus erythematosus [PDF]
Postgraduate Medical Journal, 1988 Summary Systemic lupus erythematosus is a common disease--studies throughout the world broadly agree on a prevalence of 1 in 1000 women. Recently an important clinical advance has come from the description of a syndrome of recurrent thrombosis, recurrent abortion and neurological disease associated with antiphospholipid antibodies.
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Phototesting and photoprotection in LE [PDF]
, 1997 Photosensitivity and induction of skin lesions following UV radiation is a common problem of patients with cutaneous and systemic forms of lupus erythematosus.
Cazenave A. +15 more
core +1 more source
Systemic Lupus Erythematosus [PDF]
BMJ, 1957 Lupus is a serious, potentially life-threatening disease. Its natural history is to culminate in a crescendo of autoimmunity and organ involvement. Difficulty arriving at the diagnosis may delay institution of therapy, which although helpful brings new problems. The fundamental understanding of this disease has made major strides. There is no consensus
openaire +6 more sources