Results 21 to 30 of about 885,361 (302)

ICF Core Sets: how to specify impairment and function in systemic lupus erythematosus [PDF]

, 2006
The World Health Organization’s International Classification of Function (ICF) is a tool to characterize and illuminate better the full of array of problems a patient faces when affected by disease.
Pisetsky, D.S., Stucki, Gerold, Cieza, A., Yarboro, C.H., Stamm, T.A., Aringer, M., Smolen, J.S., Stucki, G.   +7 more
core   +1 more source

Systemic lupus erythematosus-myositis overlap syndrome with lupus nephritis

Journal of Family Medicine and Primary Care, 2020
Systemic lupus erythematosus-myositis overlap syndrome is rare with prognostic implications. Reports suggest that systemic lupus erythematosus-myositis overlap syndrome with lupus nephritis has a variable clinical outcome.
Biswajit Dey, Vandana Rapahel, Yookarin Khonglah, Md Jamil   +3 more
doaj   +1 more source

The V_H gene repertoire of splenic B cells and somatic hypermutation in systemic lupus erythematosus [PDF]

, 2003
In systemic lupus erythematosus (SLE) it has been hypothesized that self-reactive B cells arise from virgin B cells that express low-affinity, nonpathogenic germline V genes that are cross-reactive for self and microbial antigens, which convert to high ...
Stott, DI, Gary Rowley, Fraser, N.L.W., Field, M, Fraser, NLW, Rowley, G., Field, M., Max Field, Rowley, G, David I Stott, Stott, D.I., Nicola LW Fraser   +11 more
core   +1 more source

Risk of herpes zoster in patients with systemic lupus erythematosus: a three-year follow-up study using a nationwide population-based cohort

Clinics, 2011
OBJECTIVE: The goal of the present study was to estimate the risk ratio of herpes zoster among systemic lupus erythematosus patients after disease onset compared with a cohort of patients without systemic lupus erythematosus over a three-year period ...
Hsin-Hua Chen, Yi-Ming Chen, Tzeng-Ji Chen, Joung-Liang Lan, Ching-Heng Lin, Der-Yuan Chen   +5 more
doaj   +1 more source

The Swiss Systemic lupus erythematosus Cohort Study (SSCS) - cross-sectional analysis of clinical characteristics and treatments across different medical disciplines in Switzerland [PDF]

, 2014
OBJECTIVES: To describe disease characteristics and treatment modalities in a multidisciplinary cohort of systemic lupus erythematosus (SLE) patients in Switzerland.
Stoll, T., Cohen, Clemens, Chizzolini, Carlo, Swiss Systemic Lupus Erythematosus Cohort Study Group, Hunziker, Thomas, Hauser, T., Clemens Cohen, Von Kempis, J., Stoll, Thomas, Katrin Koenig, Gayet-Ageron, Angèle, Carlo Chizzolini, Dayer, E., Koenig, K., Hunziker, T., Gregor Lindner, Chizzolini, C., François Spertini, Trendelenburg, M., Leimgruber, A., Lindner, Gregor, Ribi, C., Von Kempis, Johannes, Thomas Hauser, Eric Dayer, Annette Leimgruber, Petra Otto, Dayer, Eric, Koenig, Katrin, Cohen, C., Leimgruber, Annette, Spertini, F., Hauser, Thomas, Eisenberger, Ute, Thomas Stoll, Lindner, G., Otto, P., Ribi, Camillo, Eisenberger, U., Ute Eisenberger, Thomas Hunziker, Marten Trendelenburg, Johannes Von Kempis, Trendelenburg, Marten, Otto, Petra, Camillo Ribi, Spertini, François, Gayet-Ageron, A., Angèle Gayet-Ageron   +48 more
core   +1 more source

Determinant Factors of Morbidity in Patients with Systemic Lupus Erythematosus

Acta Médica Portuguesa, 2017
Introduction: Severity in systemic lupus erythematosus may vary from mild to even fatal consequences. There are no biomarkers to predict the disease’s prognosis.
Margarida Jacinto, Eliana Silva, Nuno Riso, Maria Francisca Moraes-Fontes   +3 more
doaj   +1 more source

FCGR3B copy number variation is associated with systemic lupus erythematosus risk in Afro-Caribbeans. [PDF]

, 2011
OBJECTIVES: To evaluate FCGR3B copy number variation (CNV) in African and European populations and to determine if FCGR3B copy number is associated with SLE and SLE nephritis risk in Afro-Caribbeans, adjusting for African genetic ancestry.
A. L. Patrick, Molokhia, Mariam, Vyse, Tim J, A. L. Roberts, M. Molokhia, McKeigue, Paul; id_orcid, T. J. Vyse, Roberts, Amy L., E. Petretto, Patrick, Alan Leslie, Aitman, Tim J, McKeigue, Paul, Aitman, Tim, M. Fanciulli, P. McKeigue, Roberts, Amy, Vyse, Tim J., Aitman, Tim J., Petretto, Enrico, T. J. Aitman, Fanciulli, Manuela, Roberts, Amy L   +21 more
core   +1 more source

Cancer complicating systemic lupus erythematosus--a dichotomy emerging from a nested case-control study [PDF]

, 2013
We determined whether any individual cancers are increased or decreased in a cohort of 595 patients with systemic lupus erythematosus (SLE) followed for up to 32 years at the University College London Hospitals Lupus Clinic, looking for any associated ...
Kenu, E, Dey, D, Isenberg, DA
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source