Results 11 to 20 of about 165,244 (251)
Systemic Lupus Erythematosus [PDF]
Clinical and Developmental Immunology, 2012 Systemic lupus erythematosus (SLE) is the prototypical autoimmune disease, associated with autoantibody production and evidence for immune complex deposition among the many aspects of its pathophysiology. SLE occurs most commonly in women during their reproductive years.
Chaim Putterman +3 more
+9 more sources
Systemic Lupus Erythematosus [PDF]
Cell, 1996 It has been estimated that about 3 in 10 000 people in Britain's cities have systemic lupus erythematosus (SLE)1 and the true figure may be higher.2 Forty years ago, approximately 50% of patients with SLE died within 4 years of diagnosis.3 Prospects have improved with refinements in therapy and the recognition of mild forms of the disease.
M S, Klein-Gitelman, M L, Miller
+7 more sources
Systemic lupus erythematosus [PDF]
Indian Journal of Dental Research, 2006 Desquamative gingival lesions are non-plaque induced inflammatory gingival lesions. It is a clinical description and not a diagnosis. These desquamative lesions represent oral manifestations of various dermatoses. Systemic lupus erythematous (SLE), one of the rare dermatoses shows desquamative lesions as the oral manifestation.
Jayakumar N +3 more
+10 more sources
Systemic Lupus Erythematosus [PDF]
BMJ, 1957 Lupus is a serious, potentially life-threatening disease. Its natural history is to culminate in a crescendo of autoimmunity and organ involvement. Difficulty arriving at the diagnosis may delay institution of therapy, which although helpful brings new problems. The fundamental understanding of this disease has made major strides. There is no consensus
openaire +4 more sources
Systemic lupus erythematosus [PDF]
BMJ, 2007 Systemic lupus erythematosus in pregnancy brings risks for the mother, and possible harm to the fetus if the disease is treated.
Lucy H, Mackillop +2 more
openaire +2 more sources
Determinant Factors of Morbidity in Patients with Systemic Lupus Erythematosus
Acta Médica Portuguesa, 2017 Introduction: Severity in systemic lupus erythematosus may vary from mild to even fatal consequences. There are no biomarkers to predict the disease’s prognosis.
Margarida Jacinto +3 more
doaj +1 more source
A Systematic Review of the Progression of Cutaneous Lupus to Systemic Lupus Erythematosus
Frontiers in Immunology, 2022 Lupus erythematosus is an autoimmune disease that may manifest in a variety of organs and tissues including the skin, kidney, brain, heart and lung. Many patients present with cutaneous lupus, where disease is often limited to the skin, but are at risk ...
Paul Curtiss +2 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Severe thrombocytopenia in antiphospholipid syndrome: a retrospective study of 432 patients
RMD OpenIntroduction Antiphospholipid syndrome (APS) is an autoimmune disease characterised by obstetric morbidity and recurrent venous and/or arterial thrombosis.
Zahir Amoura +12 more
doaj +1 more source