Results 101 to 110 of about 120,820 (237)

Pathways to Progressive Disability in Multiple Sclerosis: The Role of Glial Cells in Chronic CNS Inflammation

open access: yesGlia, EarlyView.
ABSTRACT Multiple sclerosis (MS) is the most common non‐infectious inflammatory CNS disease, characterized by progressive neurodegeneration and focal demyelinated lesions. Traditionally considered an autoimmune disease, MS is driven by the immune system's attack on CNS myelin, resulting in cumulative disability.
Volker Siffrin
wiley   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

open access: yesIbrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

open access: yesIbrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen   +10 more
wiley   +1 more source

The Relation of Vitamin D Deficiency and Activity of Systematic Lupus Erythematosis

open access: yesمجله دانشکده پزشکی اصفهان, 2016
Background: Considering the controversies regarding the association of vitamin D deficiency and disease activity in patients with systemic lupus erythematosus (SLE) and highly recommendations for investigating the effectiveness of this supplement on ...
Hadi Karimzadeh, Mohammad Shirzadi
doaj  

Mid‐trimester patch repair of a large cesarean scar dehiscence in an incarcerated gravid uterus with successful pregnancy outcome – A case report and review of literature

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract We report a case of reposition and patch repair of an incarcerated uterus with threatened rupture of uterine scar dehiscence in mid‐trimester. This review summarizes surgical procedures and techniques in the management of uterine dehiscence and rupture in the second trimester with the aim to continue the pregnancy.
Elisabeth D'Costa   +7 more
wiley   +1 more source

Human Leukocyte Antigens Assosiation with Systemic Lupus Arythematosus In Iraqi Patients

open access: yesمجله كليه طب الكندي, 2012
Background: The etiology of Systemic lupus erythematosus seems to be multifactorial including environmental as well as genetic factors. The genetic predisposition was supported by the occurrence of Systemic lupus erythematosus in more than one member of
Hyam Raouf Al-Hammamy   +3 more
doaj  

Maternal gut microbiota‐derived daidzein prevents osteoporosis in female offspring following prenatal prednisone exposure

open access: yesiMeta, EarlyView.
Prenatal prednisone therapy (PPT)/prenatal prednisone exposure (PPE) induces long bone dysplasia, reduced peak bone mass (PBM), and increased osteoporosis susceptibility in female offspring. Maternal gut microbiota metabolite daidzein (DAI) mediates PPE‐induced osteoporosis susceptibility in female adult offspring.
Chi Ma   +13 more
wiley   +1 more source

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

open access: yesInterdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li   +9 more
wiley   +1 more source

Systemic Lupus Erythematosus [PDF]

open access: yesCirculation, 1956
Leon Sokoloff   +6 more
openaire   +6 more sources

Evaluation of damage index and its association with risk factors in patients with systemic lupus erythematosus

open access: yesJournal of Research in Medical Sciences, 2011
Background: This study aimed to determine the value of damage index in patients with systemic lupus erythematosus (SLE) and the association between damage index and disease severity, flare up numbers, disease duration, and antiphospholipid antibodies ...
Zahra Sayed Bonakdar   +2 more
doaj  

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