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Systemic lupus erythematosus [PDF]
BMJ, 2006 Systemic lupus erythematosus (SLE) is a multisystem autoimmune connective tissue disorder with various clinical presentations. It is prevalent among young women with a peak age of onset between the late teens and early 40s and a female to male ratio of 9:1. It is more common in certain ethnic groups, such as people with African or Asian ancestry.
Manson Jessica J, Rahman Anisur
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Systemic lupus erythematosus [PDF]
Drug and Therapeutics Bulletin, 1996 It has been estimated that about 3 in 10 000 people in Britain's cities have systemic lupus erythematosus (SLE)1 and the true figure may be higher.2 Forty years ago, approximately 50% of patients with SLE died within 4 years of diagnosis.3 Prospects have improved with refinements in therapy and the recognition of mild forms of the disease.
M S, Klein-Gitelman, M L, Miller
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Systemic Lupus Erythematosus [PDF]
New England Journal of Medicine, 2012 Systemic lupus erythematosus (SLE) is the prototypical autoimmune disease, associated with autoantibody production and evidence for immune complex deposition among the many aspects of its pathophysiology. SLE occurs most commonly in women during their reproductive years.
Micha, Rapoport, Olga, Bloch
+9 more sources
Systemic Lupus Erythematosus [PDF]
BMJ, 1957 Lupus is a serious, potentially life-threatening disease. Its natural history is to culminate in a crescendo of autoimmunity and organ involvement. Difficulty arriving at the diagnosis may delay institution of therapy, which although helpful brings new problems. The fundamental understanding of this disease has made major strides. There is no consensus
openaire +4 more sources
Cognitive dysfunction improves in systemic lupus erythematosus: Results of a 10 years prospective study [PDF]
, 2018 Objective Cognitive impairment (CI) has been described in 3–80% of Systemic lupus erythematosus (SLE) patients but only short-term studies evaluated its over-time changes, suggesting that CI is usually a stable finding. We aimed at evaluating the changes
Alessandri, Cristiano +9 more
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Clinics, 2011 OBJECTIVE: The goal of the present study was to estimate the risk ratio of herpes zoster among systemic lupus erythematosus patients after disease onset compared with a cohort of patients without systemic lupus erythematosus over a three-year period ...
Hsin-Hua Chen +5 more
doaj +1 more source
Complement Activation in Patients With Probable Systemic Lupus Erythematosus and Ability to Predict Progression to American College of Rheumatology-Classified Systemic Lupus Erythematosus. [PDF]
, 2020 ObjectiveTo evaluate the frequency of cell-bound complement activation products (CB-CAPs) as a marker of complement activation in patients with suspected systemic lupus erythematosus (SLE) and the usefulness of this biomarker as a predictor of the ...
Alexander, Roberta Vezza +12 more
core +2 more sources
Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature [PDF]
, 2015 Macrophage activation syndrome (MAS) is a potentially fatal condition. It is a rare complication of several autoimmune disorders, including systemic lupus erythematosus (SLE) and systemic juvenile idiopathic arthritis (sJIA).
Didona, Dario +4 more
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High plasma leptin levels confer increased risk of atherosclerosis in women with systemic lupus erythematosus, and are associated with inflammatory oxidised lipids. [PDF]
, 2011 BackgroundPatients with systemic lupus erythematosus (SLE) are at increased risk of atherosclerosis, even after accounting for traditional risk factors.
Charles-Schoeman, Christina +14 more
core +2 more sources
Systemic lupus erythematosus [PDF]
Postgraduate Medical Journal, 1988 Summary Systemic lupus erythematosus is a common disease--studies throughout the world broadly agree on a prevalence of 1 in 1000 women. Recently an important clinical advance has come from the description of a syndrome of recurrent thrombosis, recurrent abortion and neurological disease associated with antiphospholipid antibodies.
openaire +3 more sources