Results 131 to 140 of about 295,397 (306)

Control of lupus nephritis by changes of gut microbiota

Microbiome, 2017
Systemic lupus erythematosus, characterized by persistent inflammation, is a complex autoimmune disorder with no known cure. Immunosuppressants used in treatment put patients at a higher risk of infections.
Qinghui Mu, Husen Zhang, X. Liao, Kaisen Lin, Hualan Liu, Hualan Liu, M. Edwards, S. Ahmed, Ruoxi Yuan, Liwu Li, T. Cecere, David B. Branson, Jay L. Kirby, Poorna Goswami, Caroline M. Leeth, Kaitlin A. Read, Kenneth J. Oestreich, M. Vieson, C. Reilly, C. Reilly, Xin M. Luo   +20 more
semanticscholar   +1 more source

Identification of histone deacetylase inhibitor targeting type I interferon and B‐cell abnormalities in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is characterized by increased type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama, Hachiro Konaka, Yasuhiro Kato, Takayuki Shibahara, Chisato Nishizawa, Kohei Tsujimoto, JeongHoon Park, Eri Itotagawa, Tatsunori Jo, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Wataru Aoki, Ken J Ishii, Hyota Takamatsu, Atsushi Kumanogoh   +16 more
wiley   +1 more source

CircRTN4 aggravates mesangial cell dysfunction by activating the miR-513a-5p/FN axis in lupus nephritis

, 2022
Xinyan Miao, Yuexin Tian, Lunbi Wu, Hang Zhao, Jinxi Liu, Fan Gao, Wei Zhang, Qingjuan Liu, Huifang Guo, Lin Yang, Ran Yang, Xiaojuan Feng, Shuxia Liu   +12 more
openalex   +1 more source

Defining Optimally Safe and Effective Blood Levels of Hydroxychloroquine in Lupus: An Important Step toward Precision Drug Monitoring

Arthritis &Rheumatology, Accepted Article.
Background Using hydroxychloroquine (HCQ) dose of 5 mg/kg/day in systemic lupus erythematosus (SLE) is associated with a higher risk of flares; HCQ blood level monitoring could be a better way to adjust HCQ dose. We studied the upper threshold for a reference range of HCQ levels to inform routine monitoring.
Shivani Garg, Benoît Blanchet, Yann Nguyen, Fauzia Hollnagel, Ada Clarke, Michelle Petri, Murray B. Urowitz, John G. Hanly, Caroline Gordon, Sang‐Cheol Bae, Juanita Romero‐Diaz, Jorge Sanchez‐Guerrero, Ann E. Clarke, Sasha Bernatsky, Daniel J. Wallace, David A. Isenberg, Anisur Rahman, Joan T. Merrill, Paul R. Fortin, Dafna D. Gladman, Ian N. Bruce, Ellen M. Ginzler, Mary Anne Dooley, Rosalind Ramsey‐Goldman, Susan Manzi, Andreas Jönsen, Graciela S. Alarcón, Ronald F. Van Vollenhoven, Cynthia Aranow, Véronique Le Guern, Meggan Mackay, Guillermo Ruiz‐Irastorza, S. Sam Lim, Murat Inanc, Kenneth C. Kalunian, Søren Jacobsen, Christine A. Peschken, Diane L. Kamen, Anca Askanase, Jill Buyon, Julie Chezel, Alicja Puszkiel, Nathalie Costedoat‐Chalumeau   +42 more
wiley   +1 more source

Anti phospholipid Syndrome Nephropathy in Patients with Lupus Nephritis

مجله دانشکده پزشکی اصفهان, 2008
Increasing the Antiphospholipid-nephropathy (APS-N) alterations on lupus renal lesions cause renal disease progression and detoriation of prognosis. The aim of this study was to find some indicators in lupus patients that can predict the occurring ...
Ali Sadoogh Abbasian, Zahra Seyed Bonakdar, Diana Taheri   +2 more
doaj  

Factors influencing self-management behaviors in persons with lupus nephritis: A cross-sectional study

Belitung Nursing Journal
Background: Patients with lupus nephritis experience disease symptoms and side effects from treatment. Although self-management behaviors are important in patients with this disease, there is limited research on the factors influencing these behaviors ...
Sirikarn Hanrop, Aurawamon Sriyuktasuth, Kanaungnit Pongthavornkamol, Noppawan Piaseu, Ratana Chawanasuntorapoj   +4 more
doaj   +1 more source

Circulating CD19 CD24hi CD38hi Regulatory B Cells Percentage in Lupus Nephritis Patients: Does It Differ? [PDF]

, 2022
Nihal Fathi, Rania M. Gamal, Eman M. Shawky, ‏Helal F. Hetta, Asmaa M. Zahran, Marwa Mahmoud Abdelaziz   +5 more
openalex   +1 more source

Genetic Risk Factors in Lupus Nephritis and IgA Nephropathy - No Support of an Overlap

, 2010
Background: IgA nephropathy (IgAN) and nephritis in Systemic Lupus Erythematosus (SLE) are two common forms of glomerulonephritis in which genetic findings are of importance for disease development.
Fernström, Anders, Gunnarsson, Iva, Jacobson, Stefan H., Lundberg, Sigrid, Padyukov, Leonid, Svenungsson, Elisabet, Syvanen, Ann-Christine, Thi Do, Lieu, Tuyet Vuong, Mai, Wramner, Lars   +9 more
core   +1 more source

Nationwide temporal trends in adverse pregnancy outcomes and treatments in systemic lupus erythematosus pregnancy over two decades in Sweden

Arthritis &Rheumatology, Accepted Article.
Objective This nationwide descriptive study examined temporal trends in adverse pregnancy outcomes (APOs) and treatments in systemic lupus erythematosus (SLE) pregnancies in Sweden over 2003‐2022. Methods Using nationwide Swedish registers, we identified 1,417 pregnancies of women with prevalent SLE and delivery dates in 2003‐2022, and matched them to ...
Ngoc V. Nguyen, Anna Sandström, Annica Dominicus, Elisabet Svenungsson, Karin Hellgren, Julia F. Simard, Elizabeth V. Arkema   +6 more
wiley   +1 more source

Plasma C4d as marker for lupus nephritis in systemic lupus erythematosus

Arthritis Research & Therapy, 2017
Background In the present study, we sought to evaluate the complement activation product C4d as a marker for lupus nephritis in systemic lupus erythematosus (SLE).
Myriam Martin, Karolina I. Smoląg, Albin Björk, Birgitta Gullstrand, Marcin Okrój, Jonatan Leffler, Andreas Jönsen, Anders A. Bengtsson, Anna M. Blom   +8 more
doaj   +1 more source