Results 151 to 160 of about 109,330 (215)

Nucleases and Their Inhibitors: Exploring Biological Roles, Industrial Applications, and Challenges in Heterologous Expression

open access: yesBiotechnology Journal, Volume 21, Issue 9, September 2026.
Graphical Abstract and Lay Summary Intracellular nucleases, depicted as blue circles in a nucleosome, hydrolyze phosphodiester bonds, repair damaged DNA using DNA base excision repair (BER), mismatch repair (MMR), and homologous recombination (HR), and are involved in DNA replication.
Wian Vermeulen   +2 more
wiley   +1 more source

IgA Nephropathy in a Patient with Systemic Lupus Erythematosus

open access: yesTurkish Journal of Nephrology, 2019
Systemic lupus erythematosus (SLE) is an autoimmune disorder. One of the most typical aspects of SLE is renal involvement. Lupus nephritis is a serious disease whose prognosis can usually be improved dramatically by treatment.
Süleyman KARAKÖSE   +4 more
doaj  

SLE Presenting With Unilateral Loculated Pleural Effusion in a Young Hypertensive Female: A Rare Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT SLE can rarely present with unilateral pleural effusion or hypertension. A 28‐year‐old woman with loculated exudative pleural effusion was diagnosed with SLE and lupus nephritis fulfilling EULAR/ACR criteria, treated with pigtail drainage, corticosteroids, and hydroxychloroquine, with good recovery.
Amrit Tripathi   +4 more
wiley   +1 more source

Volumetric Microsampling for Patient‐Centric Therapeutic Drug Monitoring in Clinical Pharmacology: A Scoping Review

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 9, September 2026.
Abstract Accurate drug concentration measurement is essential for precision pharmacotherapy, but conventional therapeutic drug monitoring (TDM) requires venous sampling, increasing patient burden, and potentially limiting participation in TDM and model‐informed precision dosing (MIPD).
Hari Prabhath Tummala   +5 more
wiley   +1 more source

Prognosis of Patients Infected With Talaromyces marneffei Across Various Risk Factors

open access: yesJournal of General and Family Medicine, Volume 27, Issue 5, September 2026.
ABSTRACT Background Talaromyces marneffei (TM) is an opportunistic infectious fungus, and more patients in HIV‐negative populations are infected with TM. Methods We reviewed the adult patients with TM infections (TMIs) between November 1, 2020 and April 30, 2025.
JiaXin Wang, YaoMin Wang, RenDing Wang
wiley   +1 more source

Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang   +10 more
wiley   +1 more source

Autologous Epstein–Barr virus-specific adoptive T-cell therapy in a patient with lupus nephritis

open access: yes
Objectives Dysregulation of Epstein–Barr virus (EBV)-specific cellular immunity has been hypothesised as one of the contributing factors in the pathogenesis of systemic lupus erythematosus (SLE).
John, George T   +13 more
core   +1 more source

When to consider an inborn error of immunity: clues for physicians

open access: yesInternal Medicine Journal, Volume 56, Issue 9, Page 1488-1499, September 2026.
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley   +1 more source

When Blood Proteins Reveal What Transcripts Miss: Immune Cell Priming and the Road to Prognostic Biomarkers in Lupus

open access: yes
Arthritis &Rheumatology, Volume 78, Issue 9, Page 1823-1825, September 2026.
Ioannis Parodis
wiley   +1 more source

Mapping the Altered Landscape of TCR Repertoire in Autoimmune Diseases

open access: yesImmunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT Autoimmune diseases arise from the breakdown of immune tolerance through complex interactions between genetic predisposition, environmental exposures, and adaptive immune responses. High‐throughput T‐cell receptor (TCR) repertoire sequencing has transformed our ability to characterize these responses, providing unprecedented insights into ...
Celine Albalaa   +3 more
wiley   +1 more source

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