Results 151 to 160 of about 109,330 (215)
Graphical Abstract and Lay Summary Intracellular nucleases, depicted as blue circles in a nucleosome, hydrolyze phosphodiester bonds, repair damaged DNA using DNA base excision repair (BER), mismatch repair (MMR), and homologous recombination (HR), and are involved in DNA replication.
Wian Vermeulen +2 more
wiley +1 more source
IgA Nephropathy in a Patient with Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is an autoimmune disorder. One of the most typical aspects of SLE is renal involvement. Lupus nephritis is a serious disease whose prognosis can usually be improved dramatically by treatment.
Süleyman KARAKÖSE +4 more
doaj
ABSTRACT SLE can rarely present with unilateral pleural effusion or hypertension. A 28‐year‐old woman with loculated exudative pleural effusion was diagnosed with SLE and lupus nephritis fulfilling EULAR/ACR criteria, treated with pigtail drainage, corticosteroids, and hydroxychloroquine, with good recovery.
Amrit Tripathi +4 more
wiley +1 more source
Abstract Accurate drug concentration measurement is essential for precision pharmacotherapy, but conventional therapeutic drug monitoring (TDM) requires venous sampling, increasing patient burden, and potentially limiting participation in TDM and model‐informed precision dosing (MIPD).
Hari Prabhath Tummala +5 more
wiley +1 more source
Prognosis of Patients Infected With Talaromyces marneffei Across Various Risk Factors
ABSTRACT Background Talaromyces marneffei (TM) is an opportunistic infectious fungus, and more patients in HIV‐negative populations are infected with TM. Methods We reviewed the adult patients with TM infections (TMIs) between November 1, 2020 and April 30, 2025.
JiaXin Wang, YaoMin Wang, RenDing Wang
wiley +1 more source
Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities
Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang +10 more
wiley +1 more source
Autologous Epstein–Barr virus-specific adoptive T-cell therapy in a patient with lupus nephritis
Objectives Dysregulation of Epstein–Barr virus (EBV)-specific cellular immunity has been hypothesised as one of the contributing factors in the pathogenesis of systemic lupus erythematosus (SLE).
John, George T +13 more
core +1 more source
When to consider an inborn error of immunity: clues for physicians
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley +1 more source
Arthritis &Rheumatology, Volume 78, Issue 9, Page 1823-1825, September 2026.
Ioannis Parodis
wiley +1 more source
Mapping the Altered Landscape of TCR Repertoire in Autoimmune Diseases
ABSTRACT Autoimmune diseases arise from the breakdown of immune tolerance through complex interactions between genetic predisposition, environmental exposures, and adaptive immune responses. High‐throughput T‐cell receptor (TCR) repertoire sequencing has transformed our ability to characterize these responses, providing unprecedented insights into ...
Celine Albalaa +3 more
wiley +1 more source

