Results 171 to 180 of about 295,397 (306)
Clinical and Translational Science, Volume 19, Issue 2, February 2026.ABSTRACT ASP1617 is a novel, highly selective inhibitor of cathepsin‐S, an important protease for antigen peptide loading onto major histocompatibility complex class II molecules. Preclinically, ASP1617 prevented progression of lupus‐like glomerulonephritis in an NZB/W F1 mouse model of systemic lupus erythematosus.
Tomoki Kojima +9 more
wiley +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
An Overlapping Case of Lupus Nephritis and IgG4-Related Kidney Disease
, 2015 Mazen Zaarour +4 more
openalex +2 more sources
PBLD Orchestrates the STING‐Mediated Antiviral Immune Response and Autoimmune Diseases
Advanced Science, Volume 13, Issue 4, 19 January 2026.During viral infection, PBLD expression is downregulated, thereby subverting host antiviral defenses and promoting viral replication. This study identifies PBLD as a positive regulator of STING‐induced type I interferon activation and delineated the molecular network underlying PBLD‐mediated antiviral immunity and autoimmune pathogenesis, highlighting ...
Peili Hou +17 more
wiley +1 more source
Coexisting Tubulointerstitial Inflammation and Damage Is a Risk Factor for Chronic Kidney Disease in Patients With Lupus Nephritis [PDF]
Hyemin Jeong +6 more
openalex +1 more source
The immunoregulatory axis (programmed death‐1/programmed death ligand‐1) on CD4+ T cells in lupus nephritis: association with vitamin D and chemokine C‐X‐C motif ligand 12 [PDF]
, 2021 Sara Youssry, Amina Hussein, Mai Moaaz
openalex +1 more source
Clinical Case Reports, Volume 14, Issue 1, January 2026.ABSTRACT Kidney transplantation increases the survival rate of end‐stage renal disease patients; however, acute rejection and glomerulonephritis, such as the uncommon non‐lupus full‐house nephropathy (NLFHN), can lead to graft dysfunction. NLFHN exhibits a characteristic lupus immunofluorescence pattern in the absence of systemic lupus features, which ...
Tala Pourlak, Farahnoosh Farnood
wiley +1 more source
International Journal of Retina and VitreousBackground It is evident that the physiopathological pathways of ocular and renal microvascular tissues in patients with systemic lupus are similar. Previously, this was confirmed by employing traditional fundus examination, optical coherence tomography,
Ahmed Ibrahim Basiony +3 more
doaj +1 more source
Interobserver Agreement on Histopathological Lesions in Class III or IV Lupus Nephritis [PDF]
, 2014 Suzanne Wilhelmus +6 more
openalex +1 more source
Clinical Case Reports, Volume 14, Issue 1, January 2026.ABSTRACT Sinomenine, derived from Sinomenium acutum, is widely used in inflammatory diseases. However, its risk of inducing agranulocytosis is not widely appreciated. We report a life‐threatening case in a 40‐year‐old woman with chronic kidney disease (CKD; baseline estimated glomerular filtration rate [eGFR] as low as 36 mL/min/1.73 m2) who developed ...
Ping Xin, Ruoyan Liu, Yu Zhang, Bin Fu
wiley +1 more source