Results 181 to 190 of about 37,260 (216)
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Basophils and Nephritis in Lupus

New England Journal of Medicine, 2010
Activated basophils in the circulation, lymph nodes, and spleen may augment the risk of nephritis in systemic lupus erythematosus.
Kaveri, Srini   +2 more
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The management of lupus nephritis

The Nurse Practitioner, 2014
Lupus nephritis is one of the most devastating complications of systemic lupus erythematosus. New treatment approaches and recommendations aim to decrease mortality and improve quality of life and outcomes. The role of the primary care provider is essential to help manage complications of treatment and avoid organ damage.
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Doublethink in Lupus Nephritis

JAMA: The Journal of the American Medical Association, 1980
Selecting a treatment strategy for azotemic patients with lupus nephritis is a stress-inducing exercise. It has been suggested that the type and extent of glomerular abnormalities offer the best guidance for therapy. Study of percutaneous renal biopsy specimens from patients with systemic lupus erythematosus (SLE) who have proteinuria, gross or ...
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Lupus nephritis biomarkers

Clinical Immunology, 2017
Lupus nephritis (LN), a potentially destructive outcome of SLE, is a real challenge in the management of SLE because of the difficulty in diagnosing its subclinical onset and identifying relapses before serious complications set in. Conventional clinical parameters such as proteinuria, GFR, urine sediments, anti-dsDNA and complement levels are not ...
Samar, Soliman, Chandra, Mohan
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Genetics of lupus nephritis

Lupus, 2005
Susceptibility to lupus nephritis is the end-result of complex interactions between polymorphic genetic factors involved in the regulation of immune responses. In humans, genome-wide screens and candidate-gene analyses led to the identification of several loci containing potential targets (FcgRIIa, PTPN22, PD-1, IL-10) for physiopathological research ...
B R, Lauwerys, E K, Wakeland
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Pathology of lupus nephritis

Lupus, 2005
The glomerular pathology of lupus nephritis is the result of diverse immune insults which are probably of independent pathogenetic origins. Although lupus nephritis is looked upon as a classic example of immune complex-induced microvascular injury resulting from circulating DNA double stranded polynucleotide antigens/anti-DNA antibody complexes, other
E J, Lewis, M M, Schwartz
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Lupus nephritis in children

The Indian Journal of Pediatrics, 1999
Systemic lupus erythematosus (SLE) is an autoimmune disease with varied clinical manifestations. Children and adolescents comprise one-fourth of affected patients with SLE and 40-80% of them have renal involvement. Lupus nephritis (LN) may present with mild urinary abnormalities or fulminant acute nephritis and renal failure.
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Cyclophosphamide in lupus nephritis

Lupus, 2005
Although not licensed for systemic lupus erythematosus (SLE), cyclophosphamide (CYC) has become over the last two decades the most widely prescribed cytotoxic drug for lupus nephritis (LN). A PubMed search using ‘lupus nephritis and cyclophosphamide’ as key words identifies not less than 454 papers on the topic.
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Ichthyosis and lupus nephritis

QJM: An International Journal of Medicine, 2022
Drs Z Lin, K Lai, C Chen, Y Xu
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Pregnancy and Lupus Nephritis

Scandinavian Journal of Urology and Nephrology, 2001
Family planning and pregnancy are important and usually problematic issues for a young woman with lupus nephritis. Moderate renal insufficiency and previous use of alkylating cytotoxic drugs are associated with decreased fertility. Oral contraceptives containing synthetic estrogens are contraindicated in women with active lupus nephritis, uncontrolled ...
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