Results 191 to 200 of about 108,236 (258)

Equity-focused implementation to enhance access to rare disease genomic research and understand diverse perspectives. [PDF]

Genet Med
Martinez E, Serrano J, Abouhala S, Neale A, VanNoy G, Rehm HL, O'Leary M, O'Donnell-Luria A, Wojcik MH.   +8 more
europepmc   +1 more source

Mechanistic insights into HapC: A key enzyme in prodiginine biosynthesis in Hahella chejuensis

The FEBS Journal, Volume 293, Issue 17, Page 5303-5317, September 2026.
HapC catalyzes prodiginine biosynthesis through coordinated movements of its ATP‐binding, substrate‐binding, and catalytic‐swivel domains. The enzyme shows tolerance toward short‐chain MAP analogs, and docking analyses reveal key residues and structural features underlying its substrate flexibility.
Yueh‐Te Chan, Aden Dhana Rizkita, Hsin‐Ju Hsieh, Shu‐Fang Hsu, Tony Eight Lin, Wei‐Jan Huang, Kai‐Cheng Hsu, Sheila Nathan, Peiching Chang, Andrew H.‐J. Wang, Cheng‐Chung Lee   +10 more
wiley   +1 more source

TsrA modulates type III secretion system 2 expression as a co-regulator of H-NS in <i>Vibrio parahaemolyticus</i>. [PDF]

J Bacteriol
Sutanto TPW, Pratama A, Ishii E, Iida T, Matsuda S.   +4 more
europepmc   +1 more source

The Pineal Gland Is Required for Optimal Nighttime Immunity to Bacterial Infection in Larval Zebrafish

Journal of Pineal Research, Volume 78, Issue 5, September 2026.
ABSTRACT The immune response to bacterial infection demonstrates circadian rhythmicity, with heightened antibacterial immunity often observed during the daytime. This circadian‐gated immune response is believed to have evolved to synchronize peak antibacterial immunity with the increased threat of infection when active.
Gabriel Anasarias‐Dumo, Yevetta Y. Xiang, David Cumin, James F. Cheeseman, Guy R. Warman, Jonathan W. Astin, Christopher J. Hall   +6 more
wiley   +1 more source

Socioeconomic disparities and severity of gunshot injuries in Israel: a retrospective review of National Trauma Registry data from public hospitals 2019-2022. [PDF]

Inj Epidemiol
Awwad A, Abo Naser L, Ziv A, Givon A, Wolf JM, Strelzow JA, Farhat E, Luria S, Israel Trauma Group.   +8 more
europepmc   +1 more source

DrdR Negatively Modulates the Expression of Flagellar Genes via Interaction With FleQ in Xanthomonas campestris

Molecular Plant Pathology, Volume 27, Issue 9, September 2026.
Upon activation by an unknown signal, DrdR targets FleQ, inhibiting its ATPase activity and DNA binding ability. This blocks FleQ from activating the transcription of flagellar genes, downregulating gene expression and suppressing swimming motility. ABSTRACT Response regulators (RRs) of two‐component signalling systems (TCSs) containing tandem receiver
Pei‐Dong Ren, Jie Zheng, Hong‐Ying Sun, Yan‐Hua Qi, Ji‐Liang Tang, Rui‐Fang Li, Guang‐Tao Lu   +6 more
wiley   +1 more source

Bi-allelic RNU6ATAC variants cause a minor spliceopathy characterized by transcriptome-wide minor intron retention and multisystem manifestations. [PDF]

HGG Adv
Mendez R, Arriaga TM, Ma J, Bonner DE, Emami S, Levy RJ, Alsagheir A, Alhaddad B, Bakur K, Ungar RA, Matalon DR, Miller AM, Nguyen J, Smith KS, Scott SA, Liao L, Ng Z, Marwaha S, Ward A, Undiagnosed Diseases Network, Genomics Research to Elucidate the Genetics of Rare Diseases Consortium, Novacic D, Alkuraya FS, Bernstein JA, Ganesh VS, O'Donnell-Luria A, Montgomery SB, Wheeler MT.   +27 more
europepmc   +1 more source

Interpreting the functional impact of genetic variants: The need for context qualifiers. [PDF]

Am J Hum Genet
Martinelli S, Cavé H, De Luca A, DiStefano M, Karchin R, Lugones AC, O'Donnell-Luria A, Ritter DI, Tamborero D, Tolstorukov MY, Campregher PV, Tartaglia M, Sonkin D.   +12 more
europepmc   +1 more source

Microplate-based quantification of poly-γ-glutamic acid levels in biofilm samples. [PDF]

Access Microbiol
Stevenson D, MacPhee CE, Stanley-Wall N.
europepmc   +1 more source