Results 1 to 10 of about 149 (149)
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Luteinizing Hormone-Releasing Hormone
1985Luteinizing hormone-releasing hormone (LHRH), originally isolated from mammalian hypothalami, has well-established functions in mediating hypothalamic control of pituitary hormone release (Blackwell and Guillemin, 1973; Schally et al., 1973). Parvicellular hypothalamic neurons that contain LHRH project to portal vessels originating in the median ...
Lily Yeh Jan, Yuh Nung Jan
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Luteinizing Hormone Receptors in Luteinized Rat Ovaries
1973It has been demonstrated that radioiodinated HCG and LH are accumulated in vivo by mouse and rat ovaries (1–4). These observations suggested the existence of specific receptor sites for gonadotropic hormone in this target tissue. Recently, the existence of specific receptors for LH and HCG have been reported in slices of luteinized rat ovaries (5) and ...
C. Y. Lee, Robert J. Ryan
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Stability Studies on Luteinizing Hormone
Endocrinology, 1964Stability of the biological activity of luteinizing hormone to a range of conditions and agents was studied using the Parlow ovarian ascorbic acid depletion assay. Inactivation was virtually complete after performic acid oxidation, urea denaturation, heating to 100 C in solution, subjection to pH 2 at 25 C or less, reduction by sodium in liquid ammonia,
Mabelle Adams-Mayne, Darrell N. Ward
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The action of luteinizing hormone on the testis
The Journal of Steroid Biochemistry and Molecular Biology, 1991Luteinizing hormone (LH) and human chorionic gonadotrophin (hCG) receptors are coupled to intracellular effector systems, most notably adenylate cyclase, through guanyl nucleotide-binding proteins or G-proteins. The molecular mechanism involved in the dynamic coupling of the LH/hCG receptor however, are not known.
Maciel Fabiana Cornejo +7 more
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A radioimmunoassay for turkey luteinizing hormone
General and Comparative Endocrinology, 1976Abstract A radioimmunoassay for the measurement of turkey LH (TLH) is described. The antiserum used was developed against purified TLH (No. 70355). Another TLH (CG-C) preparation was used for iodination and as a reference standard. Linear logit vs log dose plots were obtained with standard between 0.10 and 16.0 ng TLH/assay tube.
B. C. Wentworth +2 more
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Endocrinology, 1976
Sixteen synthetic analogs of LH-releasing hormone (LHRH) were tested for their ability to inhibit the stimulation of LH release induced by 3 X 10(-9)M LHRH in anterior pituitary cells in monolayer culture. Half-maximal inhibition of LHRH-induced LH release was obtained with 7 analogs at concentrations which ranged from 3 X 10(-6)M to 3 X 10(-5)M.
Andrew V. Schally +9 more
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Sixteen synthetic analogs of LH-releasing hormone (LHRH) were tested for their ability to inhibit the stimulation of LH release induced by 3 X 10(-9)M LHRH in anterior pituitary cells in monolayer culture. Half-maximal inhibition of LHRH-induced LH release was obtained with 7 analogs at concentrations which ranged from 3 X 10(-6)M to 3 X 10(-5)M.
Andrew V. Schally +9 more
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Journal of Endocrinology, 1979
Adult Soay rams with low concentrations of gonadotrophins in the circulation as a result of 12 weeks of exposure to long daylengths (16 h light: 8 h darkness) were given small doses (100 ng) of synthetic luteinizing hormone releasing hormone (LH-RH) into the jugular vein two, four or seven times/day for 10 days.
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Adult Soay rams with low concentrations of gonadotrophins in the circulation as a result of 12 weeks of exposure to long daylengths (16 h light: 8 h darkness) were given small doses (100 ng) of synthetic luteinizing hormone releasing hormone (LH-RH) into the jugular vein two, four or seven times/day for 10 days.
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Luteinizing Hormone Resistance Syndromes
Annals of the New York Academy of Sciences, 1997Luteinizing hormone (LH) plays its effects on ovarian and testicular cells through binding to a specific cell surface receptor. We recently described two kindreds with LH resistance due to abnormalities of the LH receptor (LH-R) gene. Affected XY members presented with severe or mild fetal undermasculinization (female external genitalia or micropenis ...
Constantine Tsigos +2 more
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Luteinizing hormone in cervical mucus
Fertility and Sterility, 1982The presence of material like luteinizing hormone (LH) in cervical mucus has not been previously reported. In this study, we show that in human cervical mucus there is LH-like material detectable by radioimmunoassay (RIA) and by bioassay. The content of LH in the cervical mucus of five donors was measured by RIA in samples of mucus obtained daily ...
Luis Blasco +2 more
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On the Site of Action of Luteinizing Hormone
Nature, 1967THE site of action of luteinizing hormone in stimulating synthesis and secretion of ovarian steroid hormones has been the subject of some controversy. Armstrong et al.1,2 have concluded that the primary action of this gonadotropin in rat lutein and rabbit ovarian interstitial cells is to facilitate conversion of stored cholesterol to progesterone, and ...
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