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American Journal of Obstetrics and Gynecology, 2002 OBJECTIVE: Several recent reports have demonstrated the expression of luteinizing hormone-releasing hormone receptors by human ovarian and endometrial cancers.
Carsten Gründker +2 more
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, 2018 Luteinizing hormone (LH) is secreted by the pituitary gland as a heterodimeric glycoprotein acting on the gonads, regulating development and reproduction.
Livio Casarini +3 more
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STEROID PRIMING OF THE LUTEINIZING HORMONE RESPONSE TO LUTEINIZING HORMONE RELEASING HORMONE
Journal of Endocrinology, 1978Perifusion experiments were performed to study the stimulatory effects of luteinizing hormone releasing hormone (LH-RH) on the release of LH from anterior pituitary tissue. Exposure of pituitary tissue from normal male rats to LH-RH (5 ng/ml for 5 min) induced a small release of LH; in tissue from ovariectomized rats receiving no pretreatment, the ...
L V, Beck +4 more
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Journal of Medicinal Chemistry, 1975
Two varients of LH-RH, less than Glu-D-Phe-Trp-D-Ala-Leu-Arg-Pro-Gly-NH2 (I) and less than Glu-D-Phe-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHCH2CH3 (II), have been synthesized by solid-phase methods. Both peptides strongly inhibit the LH-RH induced secretion of LH in an in vitro assay; however, only I proved effective in preventing ovulation in the 4-day ...
J P, Yardley +3 more
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Two varients of LH-RH, less than Glu-D-Phe-Trp-D-Ala-Leu-Arg-Pro-Gly-NH2 (I) and less than Glu-D-Phe-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHCH2CH3 (II), have been synthesized by solid-phase methods. Both peptides strongly inhibit the LH-RH induced secretion of LH in an in vitro assay; however, only I proved effective in preventing ovulation in the 4-day ...
J P, Yardley +3 more
openaire +2 more sources
Domestic Animal Endocrinology, 1992
The secretion of luteinizing hormone-releasing hormone (LHRH) and its temporal association with pulses of luteinizing hormone (LH) was examined in ovariectomized prepuberal gilts. Push-pull cannulae (PPC) were implanted within the anterior pituitary gland and LHRH was quantified from 10 min (200 microliters) perfusate samples.
L S, Leshin +3 more
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The secretion of luteinizing hormone-releasing hormone (LHRH) and its temporal association with pulses of luteinizing hormone (LH) was examined in ovariectomized prepuberal gilts. Push-pull cannulae (PPC) were implanted within the anterior pituitary gland and LHRH was quantified from 10 min (200 microliters) perfusate samples.
L S, Leshin +3 more
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Endocrinology, 1978
To elucidate further pituitary influence on testicular function, we studied the effect of PRL, GH, and LH alone or in various combinations on the maintenance of testicular LH receptor concentration and testosterone synthesis in response to LH (testicular responsiveness) in hypophysectomized adult rats.
W B, Zipf, A H, Payne, R P, Kelch
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To elucidate further pituitary influence on testicular function, we studied the effect of PRL, GH, and LH alone or in various combinations on the maintenance of testicular LH receptor concentration and testosterone synthesis in response to LH (testicular responsiveness) in hypophysectomized adult rats.
W B, Zipf, A H, Payne, R P, Kelch
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THE LUTEINIZING HORMONE RECEPTOR
Annual Review of Physiology, 1995▪ Abstract The luteinizing hormone receptor (LHR) is a member of the subfamily of glycoprotein hormone receptors within the superfamily of G protein–coupled receptor (GPCR)/seven-transmembrane domain receptors. Over the past eight years, major advances have been made in determining the structure and function of the LHR and its gene.
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Luteinizing Hormone-Releasing Hormone
Archives of Internal Medicine, 1986To the Editor. —In their excellent review of gonadotropin-releasing hormone (GnRH) (also known as luteinizing hormone-releasing hormone [LH-RH]) in the September 1985 issue of theArchives, Hammond and Ory 1 cite the potential advantages of GnRH over conventional gonadotropin therapy for induction of spermatogenesis as rapidity, higher success rate ...
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Luteinizing-Hormone-Releasing Hormone
New England Journal of Medicine, 1977One of the exciting advances in endocrinology has been the discovery of a family of peptidic neurohormones in the hypothalamus that stimulate or inhibit the secretion of adenohypophysial hormones.
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Nature, 1960
THERE is a demand for an easy and accurate method of assaying the luteinizing fraction of gonadotrophic hormone. The present method depends upon the formation of corpora haemorrhagica in the ovaries of immature female mice after rendering their Graafian follicles mature.
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THERE is a demand for an easy and accurate method of assaying the luteinizing fraction of gonadotrophic hormone. The present method depends upon the formation of corpora haemorrhagica in the ovaries of immature female mice after rendering their Graafian follicles mature.
openaire +2 more sources