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Luteinizing-Hormone-Releasing Hormone

New England Journal of Medicine, 1977
One of the exciting advances in endocrinology has been the discovery of a family of peptidic neurohormones in the hypothalamus that stimulate or inhibit the secretion of adenohypophysial hormones.
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Stimulating luteinizing hormone

Drug Testing and Analysis, 2011
Low molecular weight luteinizing hormone (LMWLH) receptor agonists could be of interest as a potential doping substance for athletes. These orally active compounds induce the production of endogenous hormones such as testosterone in a similar way to LH.
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Assaying Luteinizing Hormone

Nature, 1960
THERE is a demand for an easy and accurate method of assaying the luteinizing fraction of gonadotrophic hormone. The present method depends upon the formation of corpora haemorrhagica in the ovaries of immature female mice after rendering their Graafian follicles mature.
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THE LUTEINIZING HORMONE RECEPTOR

Annual Review of Physiology, 1995
▪ Abstract  The luteinizing hormone receptor (LHR) is a member of the subfamily of glycoprotein hormone receptors within the superfamily of G protein–coupled receptor (GPCR)/seven-transmembrane domain receptors. Over the past eight years, major advances have been made in determining the structure and function of the LHR and its gene.
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Luteinizing Hormone Resistance Syndromes

Annals of the New York Academy of Sciences, 1997
Luteinizing hormone (LH) plays its effects on ovarian and testicular cells through binding to a specific cell surface receptor. We recently described two kindreds with LH resistance due to abnormalities of the LH receptor (LH-R) gene. Affected XY members presented with severe or mild fetal undermasculinization (female external genitalia or micropenis ...
C, Tsigos, C, Latronico, G P, Chrousos
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Associated luteinizing hormone-releasing hormone and luteinizing hormone secretion in ovariectomized gilts

Domestic Animal Endocrinology, 1992
The secretion of luteinizing hormone-releasing hormone (LHRH) and its temporal association with pulses of luteinizing hormone (LH) was examined in ovariectomized prepuberal gilts. Push-pull cannulae (PPC) were implanted within the anterior pituitary gland and LHRH was quantified from 10 min (200 microliters) perfusate samples.
L S, Leshin   +3 more
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STEROID PRIMING OF THE LUTEINIZING HORMONE RESPONSE TO LUTEINIZING HORMONE RELEASING HORMONE

Journal of Endocrinology, 1978
Perifusion experiments were performed to study the stimulatory effects of luteinizing hormone releasing hormone (LH-RH) on the release of LH from anterior pituitary tissue. Exposure of pituitary tissue from normal male rats to LH-RH (5 ng/ml for 5 min) induced a small release of LH; in tissue from ovariectomized rats receiving no pretreatment, the ...
L V, Beck   +4 more
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Stereoisomers of luteinizing hormone-releasing hormone

Biochemical and Biophysical Research Communications, 1974
Summary Six decapeptide analogs of the luteinizing hormone-releasing hormone (LH-RH) were prepared with the D-isomers of pyroglutamic acid, histidine, tryptophan, tyrosine, leucine, and arginine successively replacing the corresponding L-amino acids of the hormone. [D-pGlu 1 ]-LH-RH and [D-His 2 ]-LH-RH had appreciable LH-releasing activities, 8% and
Y, Hirotsu   +3 more
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Radioimmunoassay of Luteinizing Hormone Releasing Hormone

Nature, 1973
THE isolation and characterization of hypothalamic luteinizing hormone releasing hormone (LH–RH) and its subsequent synthesis have made possible the production of an antibody specific for this decapeptide.
H M, Barker   +3 more
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Luteinizing Hormone Receptors in Luteinized Rat Ovaries

1973
It has been demonstrated that radioiodinated HCG and LH are accumulated in vivo by mouse and rat ovaries (1–4). These observations suggested the existence of specific receptor sites for gonadotropic hormone in this target tissue. Recently, the existence of specific receptors for LH and HCG have been reported in slices of luteinized rat ovaries (5) and ...
C Y, Lee, R J, Ryan
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