Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 6, Page 824-835, June 2026.ABSTRACT Objectives To determine the prognostic value of serum β‐human chorionic gonadotropin (β‐hCG) for predicting live birth following single euploid frozen‐embryo transfer (FET), and to develop and validate a prognostic model (iHOPE) for this purpose. Methods This retrospective cohort study used data from two large fertility practices.
E. Kalafat +8 more
wiley +1 more source
Luteinizing Hormone Regulates Testosterone Production, Leydig Cell Proliferation, Differentiation, and Circadian Rhythm During Spermatogenesis. [PDF]
Int J Mol SciLei T, Yang Y, Yang WX.
europepmc +1 more source
Aging Cell, Volume 25, Issue 6, June 2026.Metabolic stress induces insulin resistance and upregulates PTP1B in granulosa cells, leading to aging‐relevant ovarian dysfunction. Gengnianchun (GNC) suppresses PTP1B, restores IRS1–AKT2–GLUT4 signaling, and preserves follicles, highlighting PTP1B as a therapeutic target for ovarian dysfunction in metabolically vulnerable states.
Yanqiu Rao +6 more
wiley +1 more source
T‐Cell Biology in the Female Reproductive Tract: Relevance to HIV Infection
American Journal of Reproductive Immunology, Volume 95, Issue 6, June 2026.ABSTRACT Worldwide, most HIV infections occur across a mucosal surface during sexual contact, with women accounting for nearly half of reported new HIV infections across the globe in 2024. Most new infections in women and girls are believed to involve transmission across mucosal surfaces of the lower reproductive tract, which includes the vagina and ...
Barbara L. Shacklett +2 more
wiley +1 more source
A single blood luteinizing hormone level of triptorelin stimulation test can diagnose hypothalamic-pituitary-gonadal axis activation in girls with high body mass index. [PDF]
Front PediatrZeng B +6 more
europepmc +1 more source
Estetrol‐based combined oral contraceptives: A systematic review of clinical outcomes
Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 6, Page 983-998, June 2026.This systematic review summarizes clinical outcomes of estetrol‐containing combined oral contraceptives, showing reliable contraceptive efficacy, predictable bleeding patterns, improved well‐being, and a favorable hemostatic and metabolic profile, suggesting a promising and potentially safer alternative to ethinylestradiol‐based formulations.
Mathilde Råberg +3 more
wiley +1 more source
Temporal trends in serum testosterone and luteinizing hormone levels indicate an ongoing resetting of hypothalamic-pituitary-gonadal function in healthy men: a systematic review. [PDF]
J Endocrinol InvestSanti D +6 more
europepmc +1 more source
Clinical Endocrinology, Volume 104, Issue 6, Page 657-663, June 2026.ABSTRACT Objective An increasing number of trans individuals, particularly those who are non‐binary, desire lower testosterone doses than those outlined in current guidelines for gender affirmation. These guidelines acknowledge the need for a tailored approach to treatment, especially for non‐binary people.
Eli Ward‐Smith +4 more
wiley +1 more source
Luteinizing Hormone β-subunit Gene Polymorphisms and Androgen Levels are Less Predictive of Ovarian Response in Polycystic Ovary Syndrome <i>In vitro</i> Fertilisation Women: A Nested Case-Control Study. [PDF]
J Hum Reprod SciSuheimi I +10 more
europepmc +1 more source
Journal of Neuroendocrinology, Volume 38, Issue 6, June 2026.Abstract Disorders of gonadotropin pulsatility contribute to reproductive dysfunction in humans and are often associated with metabolic dysfunction. Hypogonadotropic hypogonadism is characterized by chronically insufficient gonadotropin hormone production, leading to reproductive and metabolic impairments, such as infertility and obesity.
Nimisha Nandankar +7 more
wiley +1 more source