Results 61 to 70 of about 2,816 (233)

Quantitative imaging for 177Lu-PSMA treatment response monitoring and dosimetry

Frontiers in Nuclear Medicine, 2023
PSMA-targeted radiopharmaceutical therapy is an established treatment option for metastatic castration-resistant prostate cancer (mCRPC). However, response rates and duration using 177Lu-PSMA-617 vary considerably between patients.
Catherine Meyer, Laszlo Szidonya, Celeste Winters, Anna Mench, Nadine Mallak, Erik Mittra   +5 more
doaj   +1 more source

CMKLR1-targeting peptide tracers for PET/MR imaging of breast cancer [PDF]

, 2019
Background: Molecular targeting remains to be a promising approach in oncology. Overexpression of G protein-coupled receptors (GPCRs) in human cancer is offering a powerful opportunity for tumor-selective imaging and treatment employing nuclear medicine.
Bandholtz, Sebastian, Beindorff, Nicola, Brenner, Winfried, Erdmann, Sarah, Exner, Samantha, Grötzinger, Carsten, Gómez, Juan Daniel Castillo, Hacht, Jan Lennart von, Koziolek, Eva Jolanthe, Niederstadt, Lars, Prasad, Sonal, Reinicke, Sandy, Wagener, Asja   +12 more
core   +1 more source

Stabilization of Single Metal Atoms on Graphitic Carbon Nitride: Synthetic Strategies and Emerging Applications

Advanced Science, EarlyView.
This review highlights recent advancements in stabilizing single metal atoms on graphitic carbon nitride emphasizing innovative synthesis strategies and emerging applications in electrocatalysis, photocatalysis and organic transformations, along with key challenges and future perspective. Abstract Emerging as a new frontier in catalysis science, single‐
Wenyao Zhang, Junjie Cui, Zhenjie Yao, Boyuan Zhu, Nithinraj Panangattu Dharmarajan, Ajayan Vinu, Junwu Zhu   +6 more
wiley   +1 more source

Study on Key Process Parameter for Separation and Preparation of High Abundance Ytterbium 176 Isotopes by Electromagnetic Method

Yuanzineng kexue jishu, 2023
Due to the excellent physical properties and advantages in the field of tumor therapy, lutetium 177 has attracted extensive attention in the field of internal radiation therapy in nuclear medicine.
XU Kun;REN Xiuyan;WU Dan;LI Ziying;LUO Feng;LIANG Shuang;YUAN Bo;FENG Zhe;ZENG Ziqiang;WANG Guobao;ZHAO Chunrui
doaj  

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Advances in ¹⁷⁷Lu-PSMA and ²²⁵Ac-PSMA Radionuclide Therapy for Metastatic Castration-Resistant Prostate Cancer

Pharmaceutics, 2022
For patients with metastatic castration-resistant prostate cancer (mCRPC), the survival benefit of classic treatment options with chemotherapy and drugs targeting androgen signaling is limited.
Sui Wai Ling, Erik de Blois, Eline Hooijman, Astrid van der Veldt, Tessa Brabander   +4 more
doaj   +1 more source

Determination of conditions for optimum labeling of DOTA-Y3-Octreotate with terbium-161 [abstract] [PDF]

, 2007
only availableDOTA-Y3-Octreotate (DOTA-TATE) and other somatostatin analogs can be labeled with radionuclides for cancer-fighting applications. Specifically, the radiolanthanides are of great interest to the radiopharmaceutical industry because of their ...
Cantorias, Melchor V., Cutler, Cathy S., Engelbrecht, Hendrik P., Somashekar, C., Spatola, Bradley   +4 more
core  

Imaging to study solid tumour origin and progression: lessons from research and clinical oncology [PDF]

, 2017
Biomedical imaging in recent decades has clarified our understanding of normal and pathological cellular processes in vivo. In particular, this approach recently provided insights into processes occurring at a molecular or genetic level rather than at ...
Beyer T, Friedl P, Fuster D, Giovanni Zito, Lyons SK, Stefania Raimondo   +5 more
core   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source