Results 41 to 50 of about 459 (136)

Attenuated Bacteria‐Based Tumor Therapy: Clinical Application Risks, Marketing Approval Restrictions, and Coping Strategies

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This review comprehensively overviews attenuated bacteria‐based tumor therapy, highlighting key methodologies and recent progress. It examines strategies for enhancing safety, stabilizing efficacy, optimizing manufacturing, and navigating regulatory pathways.
Yucheng Liu, Junhong Yao, Jiaxin Deng, Minjie Zhou, Kaiyue Shen, Shishuo Sun, Xiaoge Gao, Qing Zhang, Haiheng Xu   +8 more
wiley   +1 more source

A Comprehensive Review of the Multitarget Effects of Subinhibitory Concentrations of Essential Oils Against Salmonella

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 2, March 2026.
ABSTRACT Essential oils (EOs) exhibit antimicrobial activity against foodborne pathogens due to their chemical composition. This review investigates the mechanisms of action of EOs at subinhibitory concentrations against Salmonella strains. Even at subinhibitory concentrations, EOs induce cellular stress and modulate bacterial metabolism. EOs interfere
Carolina Ramos, Yhan S. Mutz, Leticia Tessaro, Bruno Dutra da Silva, Marciane Magnani, Carlos Adam Conte‐Junior   +5 more
wiley   +1 more source

Azospirillum brasilense Az39, a model rhizobacterium with AHL quorum quenching capacity [PDF]

, 2019
AimsThe aim of this research was to analyze the Quorum sensing (QS) and Quorum quenching (QQ) mechanisms based on N‐acyl‐L‐homoserine lactones (AHLs) in A.
Cassán, F., Coniglio, A., Cámara, M., Gualpa, J., Halliday, N., Lopez, G., Nievas, S.   +6 more
core   +2 more sources

SUPER: Upcycling Genetic Parts for Precise Gene Expression Control, Leakage Minimization, and Genetic Circuit Stability

Advanced Science, Volume 13, Issue 12, 27 February 2026.
To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo, Dongwon Park, Woosub Shin, Jongmin Kim   +3 more
wiley   +1 more source

Pan‐Genomic and Phenotypic Characterisation of Petroleum Hydrocarbon Degradation by Pseudomonas Species

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Pseudomonas is one of the most significant bacterial genus involved in the petroleum hydrocarbon bioremediation. Innovatively, through pan‐genomic analysis at the genus level, we found that different Pseudomonas strains have excellent complementarity at the nodes of the degradation pathway of petroleum hydrocarbons.
Xiaopeng Guo, Shuhua Zhu, Ning Zhu, Shuhan Zhang, Shenghui Yang, Guanghong Luo, Hongbin Li, Yonggang Wang, Jing Sun, Borong Ma   +9 more
wiley   +1 more source

Quorum sensing architecture network in Escherichia coli virulence and pathogenesis [PDF]

, 2023
Escherichia coli is a Gram-negative commensal bacterium of the normal microbiota of humans and animals. However, several E. coli strains are opportunistic pathogens responsible for severe bacterial infections, including gastrointestinal and urinary tract
Anabela Borges, Flament Simon, SC, Mayer, C, Simoes, M   +3 more
core   +1 more source

A short peptide derived from late embryogenesis abundant proteins enhances acid tolerance in Escherichia coli via modulation of two‐component regulatory systems

The FEBS Journal, Volume 293, Issue 3, Page 781-805, February 2026.
Expression of the LEA‐K peptide in E. coli BL21 (DE3) improved bacterial viability under acidic stress (pH4), suggesting a protective function. RNA‐sequencing of LEA‐K‐expressing vs. non‐expressing cells revealed 283 differentially expressed genes (DEGs). In silico docking linked LEA‐K to two‐component systems (TCS) proteins (Rcs, BtsS/R, and EnvZ/OmpR)
Khaled Metwally, Shinya Ikeno
wiley   +1 more source

Emerging Threat of Vibrio alginolyticus in Mediterranean Aquaculture: Virulence, Antibiotic Resistance, and Innovative Control Strategies

Aquaculture Research, Volume 2026, Issue 1, 2026.
Vibrio alginolyticus is an opportunistic marine pathogen increasingly associated with disease outbreaks in Mediterranean aquaculture, affecting fish, shrimp, and shellfish. The semi‐enclosed nature of the Mediterranean Sea, combined with rising seawater temperatures and intensive farming practices, creates favorable conditions for the persistence and ...
Rim Lajnef, Sara Thabet, Lotfi Ben Abdallah   +2 more
wiley   +1 more source

Action Mechanism of Essential Oils or Their Components Against Pathogenic Bacteria: Literature Review

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Essential oils (EOs), derived from medicinal and aromatic plants, are natural mixtures of volatile, oily compounds with varying compositions and antibacterial mechanisms. Understanding the mechanisms of EOs and their components (EOCs) is essential for predicting their impacts on various microbes and their interactions with antibiotics.
Mohamed A. El-Sakhawy, Abd El Raheim Mohammed Donia, Tawfiq N. Juraybi, Abeer Ali El-Sherbiny Ateya, Wadah Osman, Amr A. Abd-Elghany, Mohamed Mostafa Soliman, Abdel Naser A. Kobisi, Mohamed A. Balah, Shweta Negi   +9 more
wiley   +1 more source

Effects on LuxR‐Regulated Bioluminescence of Cyclodextrin‐Acyl‐L‐Homoserine Lactone Hybrids

ChemBioChem, Volume 26, Issue 19, October 3, 2025.
Cyclodextrin‐N‐acyl‐L‐Homoserine‐Lactone conjugates are synthetized, purified and fully characterized. The study of modulation of LuxR‐regulated bioluminescence production has demonstrated that one of the compounds exhibits not only the capacity to induce bioluminescence with an EC50 value of 64 µM, but also the ability to reduce bioluminescence with ...
Nicolas Tinet, David Lesur, Yves Queneau, Laurent Soulère, Florence Djedaini‐Pilard, Véronique Bonnet   +5 more
wiley   +1 more source