Results 51 to 60 of about 459 (136)

Additional file 2 of Genomic characterization of bacteria from the ultra-oligotrophic Madison aquifer: insight into the archetypical LuxI/LuxR and identification of novel LuxR solos

, 2021
Additional file 2. Interproscan output of a successfully validated luxR homolog. Each accession number corresponds to a detected protein domain.
Wengert, Peter C., Wong, Narayan H., Barton, Hazel A., Gan, Han Ming, Hudson, André O., Savka, Michael A.   +5 more
openaire   +1 more source

LuxR Solos are Becoming Major Players in Cell-Cell Communication in Bacteria

, 2016
The most common quorum sensing (QS) system in Gram-negative bacteria occurs via N-acyl homoserine lactone (AHLs) signals. An archetypical system consists of a LuxI-family protein synthesizing the AHL signal which binds at quorum concentrations to the cognate LuxR-family transcription factors which then control gene expression by binding to specific ...
Vittorio Venturi, Brian M.M. Ahmer
openaire   +3 more sources

Current status and future perspectives of multi‐modal bacteria‐based cancer therapies

Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.
Bacteria exhibit inherent tumour‐targeting capabilities, particularly thriving in hypoxic tumour microenvironments (TMEs) and activating potent anti‐tumour immune responses through pathogen‐associated molecular patterns (PAMPs) and immunomodulation.
Shuai Fan, Siyu Zhu, Wenyu Wang, Yuetong Liu, Yutong Zhou, Hao Li, Bofeng Liu, Qin Xia, Lili Huang, Lei Dong   +9 more
wiley   +1 more source

Additional file 3 of Genomic characterization of bacteria from the ultra-oligotrophic Madison aquifer: insight into the archetypical LuxI/LuxR and identification of novel LuxR solos

, 2021
Additional file 3. Genomic analyses of eight Ochrobactrum pseudogrignonense strains. Analysis of strains available on NCBI and comparison to SD129 and SD316 reveal a commonality in the presence of luxR and luxI genes1.
Wengert, Peter C., Wong, Narayan H., Barton, Hazel A., Gan, Han Ming, Hudson, André O., Savka, Michael A.   +5 more
openaire   +1 more source

Transcriptomic Analyses Unveil Hydrocarbon Degradation Mechanisms in a Novel Polar Rhodococcus sp. Strain R1B_2T From a High Arctic Intertidal Zone Exposed to Ultra‐Low Sulphur Fuel Oil

Environmental Microbiology Reports, Volume 17, Issue 5, October 2025.
Cold‐adapted Rhodococcus sp. strain R1B_2T from Arctic Tupirvik Beach (Northwest Passage) degrades short‐ to long‐chain hydrocarbons in summer seawater (−1°C to 5°C) via a synergistic activity of key hydrocarbon degradation genes (alkB, CYP153, almA, and ladA), with rhlABCR‐linked rhamnolipid production supporting biodegradation.
Nastasia J. Freyria, Antoine‐Olivier Lirette, Brady R. W. O'Connor, Charles W. Greer, Lyle G. Whyte   +4 more
wiley   +1 more source

Additional file 1 of Genomic characterization of bacteria from the ultra-oligotrophic Madison aquifer: insight into the archetypical LuxI/LuxR and identification of novel LuxR solos

, 2021
Additional file 1. Detection and analysis of LuxI synthases. (A) 10kbp genetic region surrounding identified luxR homologs (red) having corresponding LuxI homologs (blue) in SD129 and SD340. (B) Interproscan output of a successfully validated luxI homolog. Each accession number corresponds to a detected protein domain.
Wengert, Peter C., Wong, Narayan H., Barton, Hazel A., Gan, Han Ming, Hudson, André O., Savka, Michael A.   +5 more
openaire   +1 more source

Quorum Sensing Inhibits Type III‐A CRISPR‐Cas System Activity Through Repressing Positive Regulators SarA and ArcR in Staphylococcus Aureus

Advanced Science, Volume 12, Issue 36, September 25, 2025.
This study proposes a novel model illustrating how quorum sensing (QS) regulates the type III‐A CRISPR‐Cas system in Staphylococcus aureus. The QS regulator AgrA suppresses CRISPR‐Cas activity by downregulating the transcriptional regulators SarA and ArcR.
Yang Li, Yuanyue Tang, Xiaofei Li, Nina Molin Høyland‐Kroghsbo, Hanne Ingmer, Xinan Jiao, Qiuchun Li   +6 more
wiley   +1 more source

Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application

Exploration, Volume 5, Issue 4, August 2025.
This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang, Shuihao Zhao, Haijie Zhao, Mingzhang Wen, Zhong Guo   +4 more
wiley   +1 more source

The GntR/VanR transcription regulator AlkR represses AlkB2 monooxygenase expression and regulates n‐alkane degradation in Pseudomonas aeruginosa SJTD‐1

mLife, Volume 4, Issue 2, Page 126-142, April 2025.
Abstract Transmembrane alkane monooxygenase (AlkB)‐type monooxygenases, especially AlkB2 monooxygenases, are crucial for aerobic degradation of the medium‐to‐long‐chain n‐alkanes in hydrocarbon‐utilizing microorganisms. In this study, we identified a GntR/VanR transcription regulator AlkR of Pseudomonas aeruginosa SJTD‐1 involved in the negative ...
Wanli Peng, Xiuli Wang, Qinchen Liu, Zhihong Xiao, Fulin Li, Nannan Ji, Zhuo Chen, Jiaying He, Junhao Wang, Zixin Deng, Shuangjun Lin, Rubing Liang   +11 more
wiley   +1 more source

Quorum sensing regulates 'swim-or-stick' lifestyle in the phycosphere [PDF]

, 2020
Interactions between phytoplankton and bacteria play major roles in global biogeochemical cycles and oceanic nutrient fluxes. These interactions occur in the microenvironment surrounding phytoplankton cells, known as the phycosphere.
Amin, S., Fei, C., Isaac, A., Ochsenkuhn, M., Shibl, A., Wang, C.   +5 more
core   +2 more sources