Current status and future perspectives of multi‐modal bacteria‐based cancer therapies
Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.Bacteria exhibit inherent tumour‐targeting capabilities, particularly thriving in hypoxic tumour microenvironments (TMEs) and activating potent anti‐tumour immune responses through pathogen‐associated molecular patterns (PAMPs) and immunomodulation.
Shuai Fan +9 more
wiley +1 more source
Comparison of the ligand-binding sites of the three Psa solos with the prototypes of QS LuxRs and PAB LuxR solos subfamily. [PDF]
, 2014 Mapping the protein residues defining the three Clusters (Cluster 1, Cluster 2 and Cluster 3 colored in green, cyan and in orange, respectively) showing the amino acid side chains that delineate the conserved core (left column) and the specificity patch (
Patrizia Ferrante (194863) +5 more
core +1 more source
Environmental Microbiology Reports, Volume 17, Issue 5, October 2025.Cold‐adapted Rhodococcus sp. strain R1B_2T from Arctic Tupirvik Beach (Northwest Passage) degrades short‐ to long‐chain hydrocarbons in summer seawater (−1°C to 5°C) via a synergistic activity of key hydrocarbon degradation genes (alkB, CYP153, almA, and ladA), with rhlABCR‐linked rhamnolipid production supporting biodegradation.
Nastasia J. Freyria +4 more
wiley +1 more source
Advanced Science, Volume 12, Issue 36, September 25, 2025.This study proposes a novel model illustrating how quorum sensing (QS) regulates the type III‐A CRISPR‐Cas system in Staphylococcus aureus. The QS regulator AgrA suppresses CRISPR‐Cas activity by downregulating the transcriptional regulators SarA and ArcR.
Yang Li +6 more
wiley +1 more source
Structure-based multiple sequence alignment of the regulatory domains of the three Psa solos with QS LuxRs and with the prototype of the PAB LuxR solos subfamily. [PDF]
, 2014 The residues belonging to Cluster 1, to Cluster 2 and Cluster 3 are highlighted in green, cyan and in orange, respectively. The 3D architecture of the boundaries of the ligand-binding site is schematized by r (roof), f (floor), p (proximal wall) and d ...
Patrizia Ferrante (194863) +5 more
core +1 more source
Regulação gênica da biossíntese de violaceína e Quorum sensing em Chromobacterium violaceum [PDF]
, 2005 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia QuímicaA Chromobacterium violaceum é uma bactéria Gram-negativa, violeta-pigmentada, aeróbica facultativa, que vive em regiões de ...
Oliveira, Cristiana Gomes de
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TRANSCRIPTOMIC AND BIOCHEMICAL APPROACHES TO UNRAVEL THE BASIS OF BACTERIAL VIRULENCE IN Pseudomonas syringae pv. actinidiae [PDF]
, 2018 Pseudomonas syringae pv. actinidiae (Psa), is a Gram-negative bacterium, aerobic, motile, able to grow epiphytically and endophytically on plants, and it is the causative agent of kiwifruit bacterial canker. Cool temperature and high humidity promote the
Alice Regaiolo
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BIOCHEMICAL AND FUNCTIONAL CHARACTERIZATION OF THE BACTERIAL PsaR1 SENSOR IN THE PSEUDOMONAS SYRINGAE PV. ACTINIDIAE-KIWIFRUIT INTERACTION [PDF]
, 2017 Kiwifruit bacterial canker, caused by Pseudomonas syringae pv. actinidiae (Psa), is responsible for important economic losses in all major areas of kiwifruit production worldwide, including Italy.
COLOMBO, TERESA +9 more
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Insights into the lifestyle of Kosakonia rice endophytes [PDF]
, 2019 Endophytes are microorganisms that live inside plants and are often beneficial for the host. Kosakonia is a novel bacterial genus which includes several species which are diazotrophic and plant-associated.
Mosquito Guillen, Susan Grace
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LuxR Solos in the Plant Endophyte Kosakonia sp. Strain KO348. [PDF]
Appl Environ Microbiol, 2020 Mosquito S +9 more
europepmc +1 more source