Results 1 to 10 of about 6,958 (200)

Census of solo LuxR genes in prokaryotic genomes [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2015
luxR genes encode transcriptional regulators that control acyl homoserine lactone-based quorum sensing (AHL QS) in Gram negative bacteria. On the bacterial chromosome, luxR genes are usually found next or near to a luxI gene encoding the AHL signal ...
Sándor Pongor   +2 more
exaly   +8 more sources

LuxR solos in Photorhabdus species [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2014
Bacteria communicate via small diffusible molecules to mediate group-coordinated behavior, a process designated as quorum sensing. The basic molecular quorum sensing system of Gram-negative bacteria consists of a LuxI-type autoinducer synthase producing ...
Helge B Bode   +2 more
exaly   +11 more sources

LuxR Solos from Environmental Fluorescent Pseudomonads

open access: yesMSphere, 2021
LuxR solos are related to quorum sensing (QS) LuxR family regulators; however, they lack a cognate LuxI family protein. LuxR solos are widespread and almost exclusively found in proteobacteria.
Kumari Sonal Choudhary   +2 more
exaly   +7 more sources

A bioinformatic survey of distribution, conservation, and probable functions of LuxR solo regulators in bacteria [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2015
LuxR solo transcriptional regulators contain both an autoinducer binding domain (ABD; N-terminal) and a DNA binding Helix-Turn-Helix domain (HTH; C-terminal), but are not associated with a cognate N-acyl homoserine lactone (AHL) synthase coding gene in ...
Zulma Suárez-Moreno   +1 more
exaly   +4 more sources

Stenotrophomonas maltophilia responds to exogenous AHL signals through the LuxR solo SmoR (Smlt1839) [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2015
Quorum Sensing (QS) mediated by Acyl Homoserine Lactone (AHL) molecules are probably the most widespread and studied among Gram-negative bacteria. Canonical AHL systems are composed by a synthase (LuxI family) and a regulator element (LuxR family), whose
Xavier Daura   +2 more
exaly   +7 more sources

Cell-Cell Signaling Proteobacterial LuxR Solos: a Treasure Trove of Subgroups Having Different Origins, Ligands, and Ecological Roles

open access: yesMSystems, 2023
Many proteobacteria possess LuxR solos which are quorum sensing LuxR-type regulators that are not paired with a cognate LuxI-type synthase. LuxR solos have been implicated in intraspecies, interspecies, and interkingdom communication by sensing ...
Cristina Bez   +2 more
exaly   +3 more sources

Expanding the LuxR-type receptor functional repertoire: Protein-protein interactions in quorum sensing regulation. [PDF]

open access: yesPLoS Pathogens
Quorum sensing (QS) enables bacteria to coordinate gene expression in response to population density, with LuxR-type transcription factors playing a central role in this process for many Gram-negative species. Traditionally understood as ligand-activated
Caleb P Mallery, Jon E Paczkowski
doaj   +2 more sources

PcsR2 Is a LuxR-Type Regulator That Is Upregulated on Wheat Roots and Is Unique to Pseudomonas chlororaphis

open access: yesFrontiers in Microbiology, 2020
LuxR solos are common in plant-associated bacteria and increasingly recognized for playing important roles in plant-microbe interkingdom signaling. Unlike the LuxR-type transcriptional regulators of prototype LuxR/LuxI quorum sensing systems, luxR solos ...
Elizabeth A Pierson   +2 more
exaly   +3 more sources

Computer-Aided Rational Engineering of Signal Sensitivity of Quorum Sensing Protein LuxR in a Whole-Cell Biosensor

open access: yesFrontiers in Molecular Biosciences, 2021
LuxR, a bacterial quorum sensing-related transcription factor that responds to the signaling molecule 3-oxo-hexanoyl-homoserine lactone (3OC6-HSL). In this study, we employed molecular dynamics simulation and the Molecular Mechanics Generalized Born ...
Jinyu Li   +14 more
doaj   +1 more source

Interactions among quorum sensing inhibitors. [PDF]

open access: yesPLoS ONE, 2013
Many pathogenic bacteria use quorum sensing (QS) systems to regulate the expression of virulence genes in a density-dependent manner. In one widespread QS paradigm the enzyme LuxI generates a small diffusible molecule of the acyl-homoserine lactone (AHL)
Rajat Anand, Navneet Rai, Mukund Thattai
doaj   +1 more source

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