Journal of Biological Chemistry, 1992 The LuxR protein is a transcriptional activator involved in regulation of the genes required for bioluminescence (lux) in the marine bacterium Vibrio fischeri. Transcription of the two divergently oriented lux operons (luxR and luxICDABEG) is activated by LuxR in the presence of a diffusible inducer (autoinducer).
G S, Shadel, T O, Baldwin
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Bacterial Subfamily of LuxR Regulators That Respond to Plant Compounds [PDF]
Applied and Environmental Microbiology, 2011 ABSTRACT Pseudomonas fluorescens are rhizobacteria known for their biocontrol properties. Several antimicrobial functions are crucial for this process, and the experiments described here investigate the modulation of their expression during the plant-bacterium interaction.
Sujatha, Subramoni +8 more
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Frontiers in Cellular and Infection Microbiology, 2015 Here we report the draft genomes and annotation of four N-acyl homoserine lactone (AHL)-producing members from the family Sphingomonadacae. Comparative genomic analyses of 62 Sphingomonadacae genomes were performed to gain insights into the distribution
Han Ming eGan +5 more
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Binding mode exploration of LuxR-thiazolidinedione analogues, e-pharmacophore-based virtual screening in the designing of LuxR inhibitors and its biological evaluation [PDF]
Journal of Biomolecular Structure and Dynamics, 2016 Master quorum sensing (QS) regulator LuxR of Vibrio harveyi is a unique member of the TetR protein superfamily. Recent studies have demonstrated the contribution of thiazolidinedione analogues in blocking QS by decreasing the DNA-binding ability of LuxR. However, the precise mechanism of thiazolidinedione analogues binding to LuxR is still unclear.
Sundaraj, Rajamanikandan +2 more
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Neighbor-Joining unrooted tree of all LuxR-containing sequences retrieved from Actinobacteria. [PDF]
, 2012 The branches colour refers to each protein architecture: LuxR are coloured in blue; REC+LuxR are coloured in red; CHD+LuxR are coloured in yellow; TPR+LuxR are coloured in light green; Pkc+LuxR are coloured in light pink; AAA+LuxR are coloured in light ...
Catarina Lopes Santos (128629) +3 more
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Global H-NS counter-silencing by LuxR activates quorum sensing gene expression [PDF]
, 2020 Bacteria coordinate cellular behaviors using a cell–cell communication system termed quorum sensing. In Vibrio harveyi, the master quorum sensing transcription factor LuxR directly regulates >100 genes in response to changes in population density.
Van Kessel, Julia C. +9 more
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LuxO controls luxR expression in Vibrio harveyi : evidence for a common regulatory mechanism in Vibrio [PDF]
, 2003 Quorum-sensing control of luminescence in Vibrio harveyi , which involves an indirect autoinducer-mediated phosphorelay signal transduction system, contrasts with the prototypical quorum-sensing system of Vibrio fischeri , in which the autoinducer and ...
Meighen, Edward A. +3 more
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A σE-Mediated Temperature Gauge Controls a Switch from LuxR-Mediated Virulence Gene Expression to Thermal Stress Adaptation in Vibrio alginolyticus. [PDF]
PLoS Pathogens, 2016 In vibrios, the expression of virulence factors is often controlled by LuxR, the master quorum-sensing regulator. Here, we investigate the interplay between LuxR and σE, an alternative sigma factor, during the control of virulence-related gene expression
Dan Gu +5 more
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Chimeric LuxR Transcription Factors Rewire Natural Product Regulation [PDF]
Angewandte Chemie, 2020 Abstract LuxR‐type transcriptional activator proteins frequently regulate the expression of biosynthetic gene clusters (BGCs). With only a fraction of bacterial BGCs being expressed under standard culturing conditions, modulation of LuxRs would provide a powerful approach to activate silent clusters.
Ruchira Mukherji +3 more
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Regulation of Vibrio mimicus metalloprotease (VMP) production by the quorum-sensing master regulatory protein, LuxR [PDF]
, 2016 Vibrio mimicus is an estuarine bacterium, while it can cause severe diarrhea, wound infection, and otitis media in humans. This pathogen secretes a relatively important toxin named V. mimicus metalloprotease (VMP).
Abdel‐Sattar, El‐Shaymaa +2 more
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