Results 51 to 60 of about 6,063 (169)
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Background: The first pathogen to be designated a “red-alert” human pathogen is Acinetobacter baumannii, which is on the list of infections that must be treated urgently with new antibiotics.
Estabraq Ali Maklef +2 more
doaj +1 more source
ABSTRACT Synthetic biology has recently proven to be a valuable tool for enhancing agriculture even in the face of environmental and biological stresses. Understanding the challenges that militate synthetic biology will assist in ensuring safe, stable, and scalable crop production.
Ben Jesuorsemwen Enagbonma +6 more
wiley +1 more source
The LuxR receptor: the sites of interaction with quorum-sensing signals and inhibitors [PDF]
The function of LuxR homologues as quorum sensors is mediated by the binding of N-acyl-l-homoserine lactone (AHL) signal molecules to the N-terminal receptor site of the proteins. In this study, site-directed mutagenesis was carried out of the amino acid residues comprising the receptor site of LuxR from Vibrio fischeri, and the ability of the L42A ...
Koch, B. +5 more
openaire +3 more sources
Expression and Quorum Sensing Regulation of Type III Secretion System Genes of Vibrio harveyi during Infection of Gnotobiotic Brine Shrimp. [PDF]
Type III secretion systems enable pathogens to inject their virulence factors directly into the cytoplasm of the host cells. The type III secretion system of Vibrio harveyi, a major pathogen of aquatic organisms and a model species in quorum sensing ...
H A Darshanee Ruwandeepika +3 more
doaj +1 more source
LuxR-type transcriptional regulators are essential for many physiological processes in bacteria, including pathogenesis. Acidovorax citrulli is a seedborne bacterial pathogen responsible for bacterial fruit blotch, which causes great losses in melon and ...
Wei Guan +8 more
doaj +1 more source
Ankh‐Score Produces Better Sequence Alignments Than AlphaFold3
ABSTRACT Protein sequence alignment is one of the most fundamental procedures in bioinformatics. Due to its many downstream applications, improvements to this procedure are of great importance. We consider two revolutionary concepts that emerged recently as candidates for improving the state‐of‐the‐art alignment methods: AlphaFold and protein language ...
Julia Malec +3 more
wiley +1 more source
Transcriptome Analysis of the Vibrio fischeri LuxR-LuxI Regulon [PDF]
ABSTRACT The Vibrio fischeri quorum-sensing signal N -3-oxohexanoyl- l -homoserine lactone (3OC6-HSL) activates expression of the seven-gene luminescence operon.
Luis Caetano M, Antunes +6 more
openaire +2 more sources
Relay Architectures and Ecological Strategies of Quorum Sensing Effects on Microbial Interactions
Quorum‐sensing activity in one population affects neighbouring populations through direct signal perception, QS‐regulated chemical effectors, or host‐ or environment‐mediated relays. Across distinct habitats, these relay architectures are associated with ecological strategies ranging from shared signal accessibility and reciprocal responsiveness to ...
Changchang Liang +5 more
wiley +1 more source
Adaptive Laboratory Evolution Rewires Pseudomonas putida for Resource‐Efficient Acetate Assimilation
Adaptive laboratory evolution selected key mutations that improved acetate tolerance in genome‐reduced Pseudomonas putida. Multi‐omic analyses showed that adaptation increased biomass yield by reallocating resources away from costly stress‐associated programs and redirecting acetate carbon toward carbon‐conserving metabolism.
Nicolás Gurdo +18 more
wiley +1 more source

